BBL 6-10 QUESTIONS AND VERIFIED
ANSWERS|100% CORRECT|GRADE A+
Each of these metabolites is a gluconeogenic precursor except one. Which one is the exception?
A. lactate
B. acetyl CoA
C. glycerol
D. pyruvate - ANSWER B
The principal organ in which gluconeogenesis occurs is the
A. kidney
B. liver
C. brain
D. intestine - ANSWER B
What mechanism is used to transport oxaloacetate out of the mitochondria and into the cytosol during
the initial steps of the gluconeogenic pathway?
A. the sodium potassium shuttle
B. the glucose alanine shuttle
C. the malate aspartate shuttle
D. the glycerol phosphate shuttle - ANSWER C
The first step in the gluconeogenic pathway (starting with pyruvate) results in the formation of
A. malate
B. oxaloacetate
C. phosphoenolpyruvate
D. aspartate - ANSWER B
Which term best describes the manner in which glycolysis and gluconeogenesis regulate one another?
A. Catabolic regulation
,B. Metabolic regulation
C. Circular regulation
D. Reciprocal regulation - ANSWER D
Which of the following is responsible for increasing blood glucose levels?
A. Insulin
B. Glycolysis
C. Glucagon
D. Catabolism - ANSWER C
If the net flux of a fructose 1,6-bisphosphate being formed from fructose 6-phosphate is zero, what is
happening on the molecular level?
A. The formation of fructose 1,6-bisphosphate is inhibited due to allosteric control.
B. The amount of fructose 1,6-bisphosphate being formed from fructose 6-phosphate is equal to the
amount of fructose 6-phosphate being formed from fructose 1,6-bisphosphate.
C. The formation of fructose 6-phosphate is inhibited due to allosteric control.
D. The amount of fructose 1,6-bisphosphate being formed from fructose 6-phosphate is greater than
the amount of fructose 6-phosphate being formed from fructose 1,6-bisphosphate. - ANSWER B
Which of the following interconversions is a site of reciprocal regulation between glycolysis and
gluconeogenesis?
A. pyruvate and phosphoenolpyruvate
B. glucose 6-phosphate and fructose 6-phosphate
C. 2-phosphoglycerate and 3-phosphoglycerate
D. glyceraldehyde 3-phosphate and dihydroxyacetone - ANSWER A
Pyruvate oxidation to Acetyl-CoA is a virtually irreversible reaction that involves:
A. 3 enzymes and 5 coenzymes
B. 3 enzymes and 3 coenzymes
C. 5 enzymes and 5 coenzymes
, D. 5 enzymes and 3 coenzymes - ANSWER A
High concentrations NADH, acetyl-CoA, and ATP inhibit the pyruvate dehydrogenase complex (PDH) by
activating which of the following enzymes?
A. dihydrolipoyl dehydrogenase
B. dihydrolipoamide acetyltransferase
C. pyruvate dehydrogenase kinase
D. pyruvate dehydrogenase phosphatase - ANSWER C
Acetyl-CoA is produced by the Pyruvate Dehydrogenase Complex by a virtually irreversible reaction.
Which of the following coenzymes is NOT involved in this reaction?
A. Coenzyme A
B. Biotin
C. FAD
D. TPP - ANSWER B
In which of the following organelles would the conversion of pyruvate to acetyl-CoA and the TCA cycle be
found?
A. nucleus
B. lysosomes
C. golgi complex
D. mitochondria
E. endoplasmic reticulum - ANSWER D
At the end of the TCA cycle, most of the energy remaining from the original glucose is stored in
A. FADH2
B. CO2
C. pyruvate
D. ATP
E. NADH - ANSWER E
ANSWERS|100% CORRECT|GRADE A+
Each of these metabolites is a gluconeogenic precursor except one. Which one is the exception?
A. lactate
B. acetyl CoA
C. glycerol
D. pyruvate - ANSWER B
The principal organ in which gluconeogenesis occurs is the
A. kidney
B. liver
C. brain
D. intestine - ANSWER B
What mechanism is used to transport oxaloacetate out of the mitochondria and into the cytosol during
the initial steps of the gluconeogenic pathway?
A. the sodium potassium shuttle
B. the glucose alanine shuttle
C. the malate aspartate shuttle
D. the glycerol phosphate shuttle - ANSWER C
The first step in the gluconeogenic pathway (starting with pyruvate) results in the formation of
A. malate
B. oxaloacetate
C. phosphoenolpyruvate
D. aspartate - ANSWER B
Which term best describes the manner in which glycolysis and gluconeogenesis regulate one another?
A. Catabolic regulation
,B. Metabolic regulation
C. Circular regulation
D. Reciprocal regulation - ANSWER D
Which of the following is responsible for increasing blood glucose levels?
A. Insulin
B. Glycolysis
C. Glucagon
D. Catabolism - ANSWER C
If the net flux of a fructose 1,6-bisphosphate being formed from fructose 6-phosphate is zero, what is
happening on the molecular level?
A. The formation of fructose 1,6-bisphosphate is inhibited due to allosteric control.
B. The amount of fructose 1,6-bisphosphate being formed from fructose 6-phosphate is equal to the
amount of fructose 6-phosphate being formed from fructose 1,6-bisphosphate.
C. The formation of fructose 6-phosphate is inhibited due to allosteric control.
D. The amount of fructose 1,6-bisphosphate being formed from fructose 6-phosphate is greater than
the amount of fructose 6-phosphate being formed from fructose 1,6-bisphosphate. - ANSWER B
Which of the following interconversions is a site of reciprocal regulation between glycolysis and
gluconeogenesis?
A. pyruvate and phosphoenolpyruvate
B. glucose 6-phosphate and fructose 6-phosphate
C. 2-phosphoglycerate and 3-phosphoglycerate
D. glyceraldehyde 3-phosphate and dihydroxyacetone - ANSWER A
Pyruvate oxidation to Acetyl-CoA is a virtually irreversible reaction that involves:
A. 3 enzymes and 5 coenzymes
B. 3 enzymes and 3 coenzymes
C. 5 enzymes and 5 coenzymes
, D. 5 enzymes and 3 coenzymes - ANSWER A
High concentrations NADH, acetyl-CoA, and ATP inhibit the pyruvate dehydrogenase complex (PDH) by
activating which of the following enzymes?
A. dihydrolipoyl dehydrogenase
B. dihydrolipoamide acetyltransferase
C. pyruvate dehydrogenase kinase
D. pyruvate dehydrogenase phosphatase - ANSWER C
Acetyl-CoA is produced by the Pyruvate Dehydrogenase Complex by a virtually irreversible reaction.
Which of the following coenzymes is NOT involved in this reaction?
A. Coenzyme A
B. Biotin
C. FAD
D. TPP - ANSWER B
In which of the following organelles would the conversion of pyruvate to acetyl-CoA and the TCA cycle be
found?
A. nucleus
B. lysosomes
C. golgi complex
D. mitochondria
E. endoplasmic reticulum - ANSWER D
At the end of the TCA cycle, most of the energy remaining from the original glucose is stored in
A. FADH2
B. CO2
C. pyruvate
D. ATP
E. NADH - ANSWER E
