WGUIC652IObjectiveIAssessmentI(NewI
2024/I2025IUpdate)IHeredityIandIGeneticsI|
IPrepIQuestionsIandIVerifiedIAnswers|I
100%ICorrect|IGradeIA
QUESTION
StemIcellsI______________________.
Answer:
HaveItheIpropertyIofIself-renewalIbyIdivision
QUESTION
ManyIspecializedIcells,IsuchIasIwhiteIbloodIcells,I_____________________
Answer:
remainIinIG0IuntilIstimulatedIbyIexternalIsignalsItoIreenterItheIcellIcycleIandIdivide.
QUESTION
DuringItheIMIcheckpoint,ItheIcellI_______________
Answer:
monitorsIattachmentIofIspindleIfiversItoIchromosomes.
QUESTION
IfIaIcellIbeginsItoIdivideIinIanIuncontrolledIway,IitI__________.
Answer:
,mayIformIaIbenignItumor.
QUESTION
InImostIcases,IcancerIcausingImutationsI____________________.
Answer:
accumulateIoverIaInumberIofIyears
QUESTION
OneItheIpropertiesIofIcancerIisIitsIabilityItoIspread,IorI________________,ItoIotherIsit
esIinItheIbody.
Answer:
metastasize
QUESTION
TheI_______________cellIcycleIcheckpointIensuresIthatIDNAIreplicaitonIhasIoccuredI
accurately.
Answer:
G2I/IM
QUESTION
ByIsequencingItheIgenomesIofIcancerIcells,IresearchersIlearnedIthatIcancerIcellsIcontai
nI_______________.
Answer:
MoreImutationsIthanIpreviouslyIthought
,QUESTION
AberrantIDNAImethylationIcanIleadItoIcancerIbecauseI_________________.
Answer:
hypermethylationIcanIinactivateIDNAIrepairIgenes
QUESTION
NameItheIthreeIcheckpointsIofIcellIcycleIreguation:
Answer:
*IG1/SItransition:IG1,IjustIbeforecellsIenterISI
*IG2/MItransition:IbetweenIG2IandIMI
*IMIcheckIpoint:ILateImetaphaseIofImitosis
QUESTION
G1I/ISIcheckpoint
Answer:
*IControlledIbyItheIRB1Itumor-suppressorIgene
*ICellsIfinishIG1IandIenterItheISIphase,IorIenterItheInondividingIstateIcalledIG-0I(G-
zero)
*ManyIspecializedIcells,Ie.g.,IWBCsIremainIinIG0IuntilIstimulatedIbyIexternalIsignalsI
toIreenterItheIcyleIandIdivide.
QUESTION
signalItransduction
, Answer:
AIcellularImolecularIpathwayIbyIwhichIanIexternalIsignalIisIconvertedIintoIaIfunctiona
lIresponse.
QUESTION
G2I/IMIcheckpoint
Answer:
ensuresIthatItheIDNAIhasIbeenIreplicatedIandIthatIanyIdamageItoItheIDNAIhasIbeenIr
epaired.
*IprogressIthroughItheIcycleIisIstoppedIuntilIdamagesIhaveIbeenIrepaired
QUESTION
MIcheckpoint
Answer:
cellImonitorsIspindleIformationIandIattachmentItoIkinetochores
*IensuresIthatIanaphaseIseparationIofIchrommosoImesIoccursInormally
QUESTION
WhatItwoIclassesIofIcell-cycleIregulatoryIgenesIareIinvolvedIinIcancer?
Answer:
1)ITumor-suppressorIgenesI(turnIoffIorIdecreaseItheIrateIofIcellIdivision)
2)IProto-oncogenesI(IencodeIproteinsIthatIcontrolInormalIcellIdivision)
QUESTION
2024/I2025IUpdate)IHeredityIandIGeneticsI|
IPrepIQuestionsIandIVerifiedIAnswers|I
100%ICorrect|IGradeIA
QUESTION
StemIcellsI______________________.
Answer:
HaveItheIpropertyIofIself-renewalIbyIdivision
QUESTION
ManyIspecializedIcells,IsuchIasIwhiteIbloodIcells,I_____________________
Answer:
remainIinIG0IuntilIstimulatedIbyIexternalIsignalsItoIreenterItheIcellIcycleIandIdivide.
QUESTION
DuringItheIMIcheckpoint,ItheIcellI_______________
Answer:
monitorsIattachmentIofIspindleIfiversItoIchromosomes.
QUESTION
IfIaIcellIbeginsItoIdivideIinIanIuncontrolledIway,IitI__________.
Answer:
,mayIformIaIbenignItumor.
QUESTION
InImostIcases,IcancerIcausingImutationsI____________________.
Answer:
accumulateIoverIaInumberIofIyears
QUESTION
OneItheIpropertiesIofIcancerIisIitsIabilityItoIspread,IorI________________,ItoIotherIsit
esIinItheIbody.
Answer:
metastasize
QUESTION
TheI_______________cellIcycleIcheckpointIensuresIthatIDNAIreplicaitonIhasIoccuredI
accurately.
Answer:
G2I/IM
QUESTION
ByIsequencingItheIgenomesIofIcancerIcells,IresearchersIlearnedIthatIcancerIcellsIcontai
nI_______________.
Answer:
MoreImutationsIthanIpreviouslyIthought
,QUESTION
AberrantIDNAImethylationIcanIleadItoIcancerIbecauseI_________________.
Answer:
hypermethylationIcanIinactivateIDNAIrepairIgenes
QUESTION
NameItheIthreeIcheckpointsIofIcellIcycleIreguation:
Answer:
*IG1/SItransition:IG1,IjustIbeforecellsIenterISI
*IG2/MItransition:IbetweenIG2IandIMI
*IMIcheckIpoint:ILateImetaphaseIofImitosis
QUESTION
G1I/ISIcheckpoint
Answer:
*IControlledIbyItheIRB1Itumor-suppressorIgene
*ICellsIfinishIG1IandIenterItheISIphase,IorIenterItheInondividingIstateIcalledIG-0I(G-
zero)
*ManyIspecializedIcells,Ie.g.,IWBCsIremainIinIG0IuntilIstimulatedIbyIexternalIsignalsI
toIreenterItheIcyleIandIdivide.
QUESTION
signalItransduction
, Answer:
AIcellularImolecularIpathwayIbyIwhichIanIexternalIsignalIisIconvertedIintoIaIfunctiona
lIresponse.
QUESTION
G2I/IMIcheckpoint
Answer:
ensuresIthatItheIDNAIhasIbeenIreplicatedIandIthatIanyIdamageItoItheIDNAIhasIbeenIr
epaired.
*IprogressIthroughItheIcycleIisIstoppedIuntilIdamagesIhaveIbeenIrepaired
QUESTION
MIcheckpoint
Answer:
cellImonitorsIspindleIformationIandIattachmentItoIkinetochores
*IensuresIthatIanaphaseIseparationIofIchrommosoImesIoccursInormally
QUESTION
WhatItwoIclassesIofIcell-cycleIregulatoryIgenesIareIinvolvedIinIcancer?
Answer:
1)ITumor-suppressorIgenesI(turnIoffIorIdecreaseItheIrateIofIcellIdivision)
2)IProto-oncogenesI(IencodeIproteinsIthatIcontrolInormalIcellIdivision)
QUESTION