By Abul K. Abbas; Andrew H. Lichtman; Shiv Pillai
9780323479783 Chapter 1-21 Complete Guide .
immune system - ANSWER: cells and molecules responsible for immunity
immune response - ANSWER: the collective and coordinated response of cells and
molecules to the introduction of a foreign substance
vaccine - ANSWER: a preparation of microbial antigen, often combined with
adjuvants, that is administered to individuals to induce protective immunity against
microbial infections
innate immunity - ANSWER: response mechanisms that exist before infection, are
capable of rapid responses to microbes, and react in essentially the same way to
repeated infections
adaptive immunity - ANSWER: the form of immunity that is mediated by
lymphocytes and is stimulated by exposure to infections agents
specific immunity - ANSWER: another name for adaptive immunity
lymphocyte - ANSWER: type of white blood cell that produces antibodies that help
destroy pathogens
antigen - ANSWER: Any foreign molecule that is specifically recognized by
lymphocytes and elicits an immune response
antibody - ANSWER: Protein that is produced by lymphocytes and that attaches to a
specific antigen.
b lymphocyte - ANSWER: a lymphocyte derived from bone marrow that provides
humoral immunity
humoral immunity - ANSWER: specific immunity produced by B cells that produce
antibodies that circulate in body fluids
cell-mediated immunity - ANSWER: type of immunity produced by T cells that attack
infected or abnormal body cells
t lymphocytes - ANSWER: provide cell-mediated immunity and are processed by the
thymus gland
active immunity - ANSWER: immunity that develops as a result of natural or
deliberate exposure to an antigen
, passive immunity - ANSWER: immunity in which antibodies are given to a person
rather than produced within the person's own body
sensitized - ANSWER: individuals who have been exposed to a foreign substance
hypersensitivity disease - ANSWER: disease caused by abnormal or excessive
immune reactions
opsonization - ANSWER: coating antigen with an antibody and enhances
phagocytosis
lymphocyte repertoire - ANSWER: the total number of antigenic specificities of the
lymphocytes of an individual
tolerance - ANSWER: immunologic unresponsiveness
autoimmune diseases - ANSWER: the immune system loses tolerance for self and
turns against certain molecules of the body
epitopes, determinants - ANSWER: the portions of antigens that are specifically
recognized by individual lymphocytes
specificity - ANSWER: ensures that distinct microbes elicit specific responses
diversity - ANSWER: enables immune system to respond to a large variety of
microbes
memory - ANSWER: leads to enhanced responses to repeated exposures to the same
microbe
specialization - ANSWER: generates responses that are optimal for defense against
different types of microbes
self-limitation - ANSWER: allows immune system to respond to newly encountered
microbes
nonreactivity to self - ANSWER: prevents injury to the host during responses to
microbes
b lymphocytes - ANSWER: only cells capable of producing antibodies; mediators of
humoral immunity
t lymphocytes - ANSWER: cells of cell mediated immunity; subdivided
helper t cells - ANSWER: secrete cytokines