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Pharmacology for Nurses A Pathophysiological Approach

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Pharmacology for Nurses A Pathophysiological Approach, 6th
Edition TEST BANK by Michael P. Adams; Norman Holland,
Verified Chapters 1 - 50, Complete Newest Version
Hormones from _____ and _______ provide for growth and maintenance of the
female reproductive organs. - ANSWER: Pituitary gland and gonads

What organs are associated with the regulation of female reproductive system? -
ANSWER: Hypothalamus, pituitary gland, ovary

Gonadotropin-releasing hormone (GnRH) is secreted from the.. - ANSWER:
Hypothalamus

Follicle stimulating hormone & leutinizing hormone secreted from the.. - ANSWER:
Pituitary

FSH & LH act on the ovary to.. - ANSWER: Cause immature ovarian follicles to begin
developing

How & when does the process of ovulation occur? - ANSWER: On day 14 of the
ovarian cycle, surge of LH secretion causes one follicle to expel its oocyte

What is the corpus luteum and how is it developed? - ANSWER: a hormone-secreting
structure that develops in an ovary after an ovum has been discharged but
degenerates after a few days unless pregnancy has begun
- developed from the ruptured follicle that remains in the ovary

Estrogen is a generic term for what 3 different hormones? - ANSWER: 1. Estradiol
2. Estrone
3. Estriol

What kind of metabolic effects does estrogen have on non-reproductive tissues? -
ANSWER: 1. maintain low blood cholesterol levels
2. facilitates calcium uptake by bones to help maintain proper bone density

Name a few responsibilities of the combination of estrogen and progesterone. -
ANSWER: 1. promotion of breast development
2. regulation of monthly changes of the uterine cycles
3. uterine endometrium becomes vascular and thickens in preparation for receiving
a fertilized egg

What does high progesterone and estrogen levels in the final third uterine cycle do?
- ANSWER: - provides negative feedback to shut off GnRH, FSH, & LH secretion

, What happens when FSH & LH is not secreted? - ANSWER: - estrogen and
progesterone levels fall, endometrium is shed, and menstrual bleeding begins

Oral contraceptives are made up of.. - ANSWER: - combination of estrogen and
progestin or
- just progestin

What is the most common estrogen used in oral contraceptives? - ANSWER: Ethinyl
estradiol

What is the most common progestin used in oral contraceptives? - ANSWER:
norethindrone

Describe the drug administration of oral contraceptives (begin date, length of
administration, etc) - ANSWER: - Begin on day 5 of the ovarian cycle
- Continue taking the drug for 21 days
- 7 days is a placebo

What does the placebo contain and what is the purpose of having a placebo? -
ANSWER: - Purpose: to promote taking the pill on a daily basis
- Some contain iron to replace iron lost from menstrual bleeding

What happens if the daily does is missed? - ANSWER: - Client takes 2 pills the
following day it was missed
- if more than 1 day is missed, client should also take other contraceptives

How do estrogen-progestin oral contraceptives work? - ANSWER: - provides negative
feedback to the pituitary to shut down secretion of FSH and LH
- no FSH and LH means no maturation of the ovarian follicle, thus preventing
pregnancy
- reduces likelihood of implantation bc of the less favourable environment to receive
an embryo
- agents are also used to prevent dysmenorrhea

What are the 3 types of estrogen-progesterone formulations? - ANSWER: 1.
monophasic
2. biphasic
3. triphasic

Which is the most common estrogen-progesterone formulation? Why? - ANSWER: -
monophasic
- delivers a constant amount of estrogen & progestin throughout the menstrual cycle

T/F: estrogen and progestin are delivered in constant amounts with biphasic
formulations - ANSWER: False
Estrogen is constant but progestin is not

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