Edition TEST BANK By Meyer Nursing, Verified Chapters 1 - 20,
Complete Newest Version
After chronic use the need to administer more drug to achieve the same drug effect
is known as
a. antagonism
b. sensitization
c. tolerance potentiation - ANSWER:c
After drug administration has occurred the amount of drug in the blood that is free
to bind to a specific target sites is / are referred to as
a. therapeutic dose
b. ED50
C. first pass
D. bioavalibility - ANSWER:D
Depot binding is said to occur when drugs
a. copete for binding sites
b. are excreted before binding
c. bind to inactive sites
d. being to their target sites - ANSWER:c
Drug metabolism mostly occurs in the ____ and usually makes a drug more ___
soluble
a. liver and fat
b. liver and water
c. kidneys and water
d. kidneys and fat - ANSWER:B
Drugs administrated ___ are absorbed more rapidly
, a. SQ
b. IV
C. IM
D. oral - ANSWER:B
repeated use of many psychoactive drugs can cause ___ which can speed up the rate
of biotransformation of these drugs as well as others
a. Drugs competition
b. enzyme inhibition
c. tolerance
d. enzyme induction - ANSWER:D
The area postrema and the median eminence represent areas in the brian where the
____ is not complete
a. phospholipid membrane
b. blood brain barrier
c. cerebrospinal fluid
d. choroid plexus - ANSWER:b
the first pass effect occurs with orally administer drugs because
a. their absorption is slowed by food
b. the drug must first survive the acidic stomach
c. salivary enzymes in the mouth begin metabolism
d. the drug absorbed into the bloodstream from the stomach goes to the liver on the
way to general circulation - ANSWER:d
Which of the following about clearance by first order kinetics is FALSE
a. molecules of drug are cleared at a constant rate regardless of drug concentration
b. molecules of drug are cleared at an exponential rate
c. constant fraction of the free drug in the blood is removed in each time interval
d. clearance of most drugs occurs in this manner - ANSWER:A
Which of the following factors does not effect the ptarmcoinetics of a drug
a. rout of administration