Psychopharmacology: Drugs, the Brain, and Behavior, 3rd
Edition TEST BANK By Meyer Nursing, Verified Chapters 1 - 20,
Complete Newest Version
The process of releasing neurotransmitter molecules from the vesicles is known as
_____ and occurs as a result of an influx of _____ - ANSWER:Exocytosis; Ca2+
Depot binding is said to occur when drugs - ANSWER:Bind to inactive sites
During the ____ period, no additional action potentials can be created -
ANSWER:Absolute refractory
Neural transmission is generally ____ within a single neuron and ____ between
neurons. - ANSWER:Electrical; chemical
The most common type of synapse in the brain is the ______ synapse -
ANSWER:Axodendritic
Neurons rely on ____ for protection, metabolic support and insulation -
ANSWER:Glial cells
Which of the following factors does NOT affect the pharmokinetics of a drug?
A) Route of Administration
B) Lipid solubility
C) Depot binding
D) Drug action - ANSWER:Drug action
The sac-like structures in the presynaptic terminal are called ______ and are filled
with _______ - ANSWER:Synaptic vesicles; neurotransmitter molecules
In addition to environmental and sensory stimuli, psychoactive drugs can trigger
long-lasting changes in neuronal connectivity. Collectively, these changes are termed
- ANSWER:Synaptic plasticity
Axonal transport of proteins occurs along a track formed by - ANSWER:Microtubules
When activated, somatodendritic autoreceptors - ANSWER:Reduce the rate of cell
firing
If a substance is a neurotransmitter, stimulation of the presynaptic cell should have
the same effect as - ANSWER:Direct application of the proposed substance to the
postsynaptic cell
, In order for a substance to be considered a neurotransmitter it must meet several
criteria. Which of the following is NOT considered a criterion for neurotransmitter
status?
A) A synthetic mechanism should be present in the presynaptic cell
B) Vesicles containing the substance should move down the axon with the action
potentials when the neuron is stimulated
C) Receptors for the proposed substance should be present on the postsynaptic cell
D) A means for inactivating the substance should be present - ANSWER:Vesicles
containing the substance should move down the axon with the action potentials
when the neuron is stimulated
The Na+/K+ pump helps to maintain the ______ by moving three Na+ ions in and
two K+ ions out of the cell - ANSWER:Resting membrane potential
Activating a metabotropic receptor can result in all of the following except for
A) Opening of a G protein-gated ion channel
B) changes in the levels of a second messenger
C)Opening of an ion channel within the receptor
D) Changes in gene expression - ANSWER:Changes in gene expression
Drug metabolism mostly occurs in the ____ and usually makes a drug more _____
soluble. - ANSWER:Liver; Water
The ____ is best described as a result of the selective permeability of the neuronal
membrane and the uneven distribution of ions inside and outside the cell. -
ANSWER:Resting membrane potential
After drug administration has occurred, the amount of drug in the blood that is free
to bind at specific target sites is/are referred to as - ANSWER:Bioavailability
In the dose-response curve, a decrease in potency is indicated by a shift -
ANSWER:To the right
_____ refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while ______ are the resulting widespread
alterations in function. - ANSWER:Drug action; drug effects
Selective blockade of terminal autoreceptors for DA would lead to a(n) -
ANSWER:Increase in neurotransmitter release
Prior to neurotransmitter release, vesicles are transported to specialized regions of
the presynaptic terminal called _____ zones, where they bind to the terminal in a
process known as ___________. - ANSWER:Priming, exocytosis.
Steroid hormones bind to ______ receptors, which act as ______ when activated,
and regulate gene expression - ANSWER:Intracellular; Transcription factors
Edition TEST BANK By Meyer Nursing, Verified Chapters 1 - 20,
Complete Newest Version
The process of releasing neurotransmitter molecules from the vesicles is known as
_____ and occurs as a result of an influx of _____ - ANSWER:Exocytosis; Ca2+
Depot binding is said to occur when drugs - ANSWER:Bind to inactive sites
During the ____ period, no additional action potentials can be created -
ANSWER:Absolute refractory
Neural transmission is generally ____ within a single neuron and ____ between
neurons. - ANSWER:Electrical; chemical
The most common type of synapse in the brain is the ______ synapse -
ANSWER:Axodendritic
Neurons rely on ____ for protection, metabolic support and insulation -
ANSWER:Glial cells
Which of the following factors does NOT affect the pharmokinetics of a drug?
A) Route of Administration
B) Lipid solubility
C) Depot binding
D) Drug action - ANSWER:Drug action
The sac-like structures in the presynaptic terminal are called ______ and are filled
with _______ - ANSWER:Synaptic vesicles; neurotransmitter molecules
In addition to environmental and sensory stimuli, psychoactive drugs can trigger
long-lasting changes in neuronal connectivity. Collectively, these changes are termed
- ANSWER:Synaptic plasticity
Axonal transport of proteins occurs along a track formed by - ANSWER:Microtubules
When activated, somatodendritic autoreceptors - ANSWER:Reduce the rate of cell
firing
If a substance is a neurotransmitter, stimulation of the presynaptic cell should have
the same effect as - ANSWER:Direct application of the proposed substance to the
postsynaptic cell
, In order for a substance to be considered a neurotransmitter it must meet several
criteria. Which of the following is NOT considered a criterion for neurotransmitter
status?
A) A synthetic mechanism should be present in the presynaptic cell
B) Vesicles containing the substance should move down the axon with the action
potentials when the neuron is stimulated
C) Receptors for the proposed substance should be present on the postsynaptic cell
D) A means for inactivating the substance should be present - ANSWER:Vesicles
containing the substance should move down the axon with the action potentials
when the neuron is stimulated
The Na+/K+ pump helps to maintain the ______ by moving three Na+ ions in and
two K+ ions out of the cell - ANSWER:Resting membrane potential
Activating a metabotropic receptor can result in all of the following except for
A) Opening of a G protein-gated ion channel
B) changes in the levels of a second messenger
C)Opening of an ion channel within the receptor
D) Changes in gene expression - ANSWER:Changes in gene expression
Drug metabolism mostly occurs in the ____ and usually makes a drug more _____
soluble. - ANSWER:Liver; Water
The ____ is best described as a result of the selective permeability of the neuronal
membrane and the uneven distribution of ions inside and outside the cell. -
ANSWER:Resting membrane potential
After drug administration has occurred, the amount of drug in the blood that is free
to bind at specific target sites is/are referred to as - ANSWER:Bioavailability
In the dose-response curve, a decrease in potency is indicated by a shift -
ANSWER:To the right
_____ refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while ______ are the resulting widespread
alterations in function. - ANSWER:Drug action; drug effects
Selective blockade of terminal autoreceptors for DA would lead to a(n) -
ANSWER:Increase in neurotransmitter release
Prior to neurotransmitter release, vesicles are transported to specialized regions of
the presynaptic terminal called _____ zones, where they bind to the terminal in a
process known as ___________. - ANSWER:Priming, exocytosis.
Steroid hormones bind to ______ receptors, which act as ______ when activated,
and regulate gene expression - ANSWER:Intracellular; Transcription factors
