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NR 566 Week 1: Open Book Quiz

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Question 1 ATTESTATION Question 2 4 / 4 pts Which antibiotic does the course textbook recommend for treating a UTI in breastfeeding women? Short-term Fluoroquinolones Rationale: This information can be found in the Summary of Key Prescribing Considerations in the chapter that covers this drug class. Question 3 4 / 4 pts Which patients being treated with a penicillin are at high risk for toxicity? (Select all that apply) Correct! renal impaired Correct! acutely ill Correct! very young Correct! very old Rationale: Renal impairment causes the half-life to increase dramatically and may necessitate a reduction in dosage. In patients at high risk for toxicity (those with renal impairment, the acutely ill, the very young, and older adults), kidney function should be monitored. p. 665 Question 4 4 / 4 pts Which antibiotic class is most likely to be given to someone with otitis media if there are no contraindications? Correct! Penicillin After 3 days of observation, start 10 days of amoxicillin or amoxicillin/clavulanate. Information found in the course module. Question 5 4 / 4 pts Locate the Prescribers' Digital Reference website () to answer this question. A patient is prescribed Amoxicillin for an infection. They have a creatinine clearance of 24mL/min. What dose of amoxicillin should they be prescribed? Correct! 250-500mg PO every 12 hours Rationale: The following dosing recommendations pertain to adults. No specific dosage adjustments for pediatric patients with renal impairment are available at this time; however, dosage intervals should be adjusted. CrCl 30 mL/min: no dosage adjustment needed. CrCl 10—30 mL/min: 250—500 mg PO every 12 hours, depending on the severity of the infection. Do not use the 875 mg-tablet strength or the extended-release tablet for dosing. CrCl 10 mL/min: 250—500 mg PO every 24 hours, depending on the severity of the infection. Do not use the 875 mg-tablet strength or the extended-release tablet for dosing.

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