step 1 synthesisof glucose G phosphate
n glucose glucose G phosphate use ATP with help of hexokinase
this reaction is irreversible
relationtopreventtransportofglucoseoutofthecell
phospho
stage1
g
phosphogucose
glucose G phosphate fructose G phosphate
Isomerase
n this reaction is reversible
thehydroxygroupofthe glucose G phosphate ismorediclicut tophosphorylate
step3 phosphorylation offructose G phosphate
n fructose G phosphate Pfk t fructose 1,6 bisphosphate
this reaction is irreversable n thefirstcommittedstepinglycolosis
n changes ATPtoADP usingtheenzyme phospholructokinase 1
PFK 1 is the most Imp regulatory enzymeforglycolosis
step4 cleavage of fructose 1 G biphosphate
this reaction is reversible
aldolase
fructose 1 6 phosphate glyceraldehyde 3 phosphate 3 dihydroxyacetone
the reaction of aldol cleavage
in aldol cleavage an aldehyde 3 a ketone are products tutotviase 3 aldotrase
eventhe reaction is unfavorable it still proceeds cause theproducts are rapidly removed
Step5 the interconversion of glyceraldehyde 3 phosphate 3 dihydroxy acetonephosphate
n this reaction is reversable
trios phosphate
glyceraldehyde 3 phosphate
Isomerase
dihydroxyacetone phosphate
n alter this reaction theglucose has been converted into twomoleculesof G 3 P
, Step 6 oxidation ofglyceraldehyde 3 phosphate
n this reaction isreversible
n it undergoes Oxydation 3 phosphorylation
N 2 glyceraldehyde 3 phosphate glycerate 1,3 bisphosphate
N NAD t Pi NADH Ht enzyme glyceraldehyde 3 phosphate dehydrogenase
n forms a bond called phospho anhydridebond
step phosphorylgrouptransfer Glycolosis
n this reaction is reversible stage2
n use the enzyme phosphoglyarate kinase
N glyarak 1,3 bisphosphate glycerate 3 phosphate
n this reaction is an example of substrate level phosphorylation
step8 the interconversion of 3 phosphoglyarate 3 2 phosphoglycerate
n is a reversible reaction
glyarak 3 phosphate glyarale 2 phosphate
n th enzyme is phosphoglyarale mutase
step 9 dehydrogenase reaction
N is a reversible reaction
n glycerate 2 phosphate phosphoenolpyruvate
n the enzyme is enolase PEP has a higher phosphorylgroup ketose form is more stable
step10 Synthesis of pyruvate
n this is an irreversible reaction
phosphoenolpyruvate pyruvate keto form
n the enzyme is pyruvate kinase ATP to ADP
n glucose glucose G phosphate use ATP with help of hexokinase
this reaction is irreversible
relationtopreventtransportofglucoseoutofthecell
phospho
stage1
g
phosphogucose
glucose G phosphate fructose G phosphate
Isomerase
n this reaction is reversible
thehydroxygroupofthe glucose G phosphate ismorediclicut tophosphorylate
step3 phosphorylation offructose G phosphate
n fructose G phosphate Pfk t fructose 1,6 bisphosphate
this reaction is irreversable n thefirstcommittedstepinglycolosis
n changes ATPtoADP usingtheenzyme phospholructokinase 1
PFK 1 is the most Imp regulatory enzymeforglycolosis
step4 cleavage of fructose 1 G biphosphate
this reaction is reversible
aldolase
fructose 1 6 phosphate glyceraldehyde 3 phosphate 3 dihydroxyacetone
the reaction of aldol cleavage
in aldol cleavage an aldehyde 3 a ketone are products tutotviase 3 aldotrase
eventhe reaction is unfavorable it still proceeds cause theproducts are rapidly removed
Step5 the interconversion of glyceraldehyde 3 phosphate 3 dihydroxy acetonephosphate
n this reaction is reversable
trios phosphate
glyceraldehyde 3 phosphate
Isomerase
dihydroxyacetone phosphate
n alter this reaction theglucose has been converted into twomoleculesof G 3 P
, Step 6 oxidation ofglyceraldehyde 3 phosphate
n this reaction isreversible
n it undergoes Oxydation 3 phosphorylation
N 2 glyceraldehyde 3 phosphate glycerate 1,3 bisphosphate
N NAD t Pi NADH Ht enzyme glyceraldehyde 3 phosphate dehydrogenase
n forms a bond called phospho anhydridebond
step phosphorylgrouptransfer Glycolosis
n this reaction is reversible stage2
n use the enzyme phosphoglyarate kinase
N glyarak 1,3 bisphosphate glycerate 3 phosphate
n this reaction is an example of substrate level phosphorylation
step8 the interconversion of 3 phosphoglyarate 3 2 phosphoglycerate
n is a reversible reaction
glyarak 3 phosphate glyarale 2 phosphate
n th enzyme is phosphoglyarale mutase
step 9 dehydrogenase reaction
N is a reversible reaction
n glycerate 2 phosphate phosphoenolpyruvate
n the enzyme is enolase PEP has a higher phosphorylgroup ketose form is more stable
step10 Synthesis of pyruvate
n this is an irreversible reaction
phosphoenolpyruvate pyruvate keto form
n the enzyme is pyruvate kinase ATP to ADP
