Nesters Microbiology A Human Perspective 8th Edition
Anderson Solutions Manual
Red throat with patches of pus and scattered tiny hemorrhages (not adenovirus) -
ANSWER: Strep Throat
Neck lymph nodes enlarged and tender (not adenovirus) - ANSWER: Strep Throat
Scarlet fever and roughening of the skin - ANSWER: Strep Throat
Many virulence factors that can alter structural components of the host or be
enzymes and toxins - ANSWER: Streptococcus pyogenes
80 subtypes of streptococcal protein that are adhesins and prevent phagocytosis due
to C3b - ANSWER: M protein
Streptococcal protein that helps in attachment to cells of the throat by adhering to
fibrin - ANSWER: Protein F
Produces DNase, hyaluronidase, and proteases to spread (does not cause
conjunctivitis) - ANSWER: Streptococcus pyogenes
Produces streptokinase to break clots - ANSWER: Streptococcus pyogenes
Produces protein G as an Fc receptor - ANSWER: Streptococcus pyogenes
Produces C5a peptidase, preventing migration of phagocytes - ANSWER:
Streptococcus pyogenes
Produces Streploysins O and S that destroy erythrocytes and leukocytes - ANSWER:
Streptococcus pyogenes
Produces SPEs, aka erythrogenic toxin, in lysogenized form, superantigens that cause
massive release of cytokines causing scarlet fever and roughening of the skin -
ANSWER: Streptococcus pyogenes
Respiratory pathogen that may also cause "flesh eating necrotizing fasciitis" -
ANSWER: Streptococcus pyogenes
Protein that prevents migration of phagocytes - ANSWER: C5a peptidase
Streptococcal protein that acts as an Fc receptor - ANSWER: Protein G
,Protein produced to break clots - ANSWER: Streptokinase
Proteins that destroy erythrocytes and leukocytes - ANSWER: Streploysins O and S
Superantigens that cause massive release of cytokines causing scarlet fever and
roughening of the skin - ANSWER: SPE
GAS - ANSWER: Group A Streptococcus
Criterion for Lancefield grouping - ANSWER: Cell wall carbohydrates
Produces a hyaluronic acid capsule - ANSWER: Streptococcus pyogenes
Type of antibodies to which Protein G bonds - ANSWER: IgG
Confirmed by diagnostic tests and throat culture - ANSWER: Strep Throat
Treat with penicillin and erythromycin (2) - ANSWER: Strep Throat, Pneumococcal
pneumonia
Long term carriers have strains that are deficient in a protein (agent and protein) -
ANSWER: Streptococcus pyogenes, M protein
Infection that leads to multiple sequelae due to immune response - ANSWER: Strep
Throat
Can occur after healing from strep throat - ANSWER: Post-Streptococcal Sequelae
Post-Streptococcal Sequelae (3) - ANSWER: Acute Rheumatic Fever, Chronic
Rheumatic Heart Disease (Subacute Endocarditis), Acute Post-Streptococcal
Glomerulonephritis
Joint pains, chest pains, rash, and nodules under the skin - ANSWER: Acute
Rheumatic Fever
Causes chorea - ANSWER: Acute Rheumatic Fever
Causes heart failure and damage to valves in 1/3 of patients - ANSWER: Acute
Rheumatic Fever
Only develops in people who are genetically predisposed due to MHC II alleles -
ANSWER: Acute Rheumatic Fever
Autoimmune response involving both humoral and cell mediated response with
antibodies against the pathogen reacting with host tissue such as cardiac myosin -
ANSWER: Acute Rheumatic Fever
, Synonym of chorea - ANSWER: Uncontrollable body movement
Synonym of uncontrollable body movement - ANSWER: Chorea
Follows Acute Rheumatic Fever - ANSWER: Chronic Rheumatic Heart Disease
Precedes Chronic Rheumatic Heart Disease - ANSWER: Acute Rheumatic Fever
Can follow Strep Throat but more commonly follows streptococcal skin infection -
ANSWER: Acute Post-Streptococcal Glomerulonephritis
Fluid retention, high BP, blood and proteins in urine (looks like Coca Cola) - ANSWER:
Acute Post-Streptococcal Glomerulonephritis
Damage due to inflammatory response to pathogen antigens that accumulate in the
kidney glomeruli - ANSWER: Acute Post-Streptococcal Glomerulonephritis
Antibodies bind to antigens of pathogen and initiate complement response -
ANSWER: Acute Post-Streptococcal Glomerulonephritis
Disease caused by a pleomorphic bacterium - ANSWER: Diphtheria
Bacterium that forms pallisades - ANSWER: Corynebacterium diphtheriae
Forms black colonies in medium containing potassium-tellurite - ANSWER:
Corynebacterium diphtheriae
Grown on Loeffler medium, enhancing volutin granules that can be seen with
methylene blue - ANSWER: Corynebacterium diphtheriae
Dramatic swelling of the neck - ANSWER: Diphtheria
Whitish-gray pseudomembrane on the tonsils, throat, or nasal cavity - ANSWER:
Diphtheria
Heart, kidney failure, and paralysis (nerve damage) may occur due to toxin in blood -
ANSWER: Diphtheria
Toxin in lysogenized strains - ANSWER: Corynebacterium diphtheriae
Structure made of dead cells, clotted blood, fibrin, and leukocytes - ANSWER:
Diphtheria Pseudomembrane
Structure that may come loose and obstruct passageway - ANSWER: Diphtheria
Pseudomembrane
Obstruction by a membrane that leads to suffocation - ANSWER: Diphtheria
Anderson Solutions Manual
Red throat with patches of pus and scattered tiny hemorrhages (not adenovirus) -
ANSWER: Strep Throat
Neck lymph nodes enlarged and tender (not adenovirus) - ANSWER: Strep Throat
Scarlet fever and roughening of the skin - ANSWER: Strep Throat
Many virulence factors that can alter structural components of the host or be
enzymes and toxins - ANSWER: Streptococcus pyogenes
80 subtypes of streptococcal protein that are adhesins and prevent phagocytosis due
to C3b - ANSWER: M protein
Streptococcal protein that helps in attachment to cells of the throat by adhering to
fibrin - ANSWER: Protein F
Produces DNase, hyaluronidase, and proteases to spread (does not cause
conjunctivitis) - ANSWER: Streptococcus pyogenes
Produces streptokinase to break clots - ANSWER: Streptococcus pyogenes
Produces protein G as an Fc receptor - ANSWER: Streptococcus pyogenes
Produces C5a peptidase, preventing migration of phagocytes - ANSWER:
Streptococcus pyogenes
Produces Streploysins O and S that destroy erythrocytes and leukocytes - ANSWER:
Streptococcus pyogenes
Produces SPEs, aka erythrogenic toxin, in lysogenized form, superantigens that cause
massive release of cytokines causing scarlet fever and roughening of the skin -
ANSWER: Streptococcus pyogenes
Respiratory pathogen that may also cause "flesh eating necrotizing fasciitis" -
ANSWER: Streptococcus pyogenes
Protein that prevents migration of phagocytes - ANSWER: C5a peptidase
Streptococcal protein that acts as an Fc receptor - ANSWER: Protein G
,Protein produced to break clots - ANSWER: Streptokinase
Proteins that destroy erythrocytes and leukocytes - ANSWER: Streploysins O and S
Superantigens that cause massive release of cytokines causing scarlet fever and
roughening of the skin - ANSWER: SPE
GAS - ANSWER: Group A Streptococcus
Criterion for Lancefield grouping - ANSWER: Cell wall carbohydrates
Produces a hyaluronic acid capsule - ANSWER: Streptococcus pyogenes
Type of antibodies to which Protein G bonds - ANSWER: IgG
Confirmed by diagnostic tests and throat culture - ANSWER: Strep Throat
Treat with penicillin and erythromycin (2) - ANSWER: Strep Throat, Pneumococcal
pneumonia
Long term carriers have strains that are deficient in a protein (agent and protein) -
ANSWER: Streptococcus pyogenes, M protein
Infection that leads to multiple sequelae due to immune response - ANSWER: Strep
Throat
Can occur after healing from strep throat - ANSWER: Post-Streptococcal Sequelae
Post-Streptococcal Sequelae (3) - ANSWER: Acute Rheumatic Fever, Chronic
Rheumatic Heart Disease (Subacute Endocarditis), Acute Post-Streptococcal
Glomerulonephritis
Joint pains, chest pains, rash, and nodules under the skin - ANSWER: Acute
Rheumatic Fever
Causes chorea - ANSWER: Acute Rheumatic Fever
Causes heart failure and damage to valves in 1/3 of patients - ANSWER: Acute
Rheumatic Fever
Only develops in people who are genetically predisposed due to MHC II alleles -
ANSWER: Acute Rheumatic Fever
Autoimmune response involving both humoral and cell mediated response with
antibodies against the pathogen reacting with host tissue such as cardiac myosin -
ANSWER: Acute Rheumatic Fever
, Synonym of chorea - ANSWER: Uncontrollable body movement
Synonym of uncontrollable body movement - ANSWER: Chorea
Follows Acute Rheumatic Fever - ANSWER: Chronic Rheumatic Heart Disease
Precedes Chronic Rheumatic Heart Disease - ANSWER: Acute Rheumatic Fever
Can follow Strep Throat but more commonly follows streptococcal skin infection -
ANSWER: Acute Post-Streptococcal Glomerulonephritis
Fluid retention, high BP, blood and proteins in urine (looks like Coca Cola) - ANSWER:
Acute Post-Streptococcal Glomerulonephritis
Damage due to inflammatory response to pathogen antigens that accumulate in the
kidney glomeruli - ANSWER: Acute Post-Streptococcal Glomerulonephritis
Antibodies bind to antigens of pathogen and initiate complement response -
ANSWER: Acute Post-Streptococcal Glomerulonephritis
Disease caused by a pleomorphic bacterium - ANSWER: Diphtheria
Bacterium that forms pallisades - ANSWER: Corynebacterium diphtheriae
Forms black colonies in medium containing potassium-tellurite - ANSWER:
Corynebacterium diphtheriae
Grown on Loeffler medium, enhancing volutin granules that can be seen with
methylene blue - ANSWER: Corynebacterium diphtheriae
Dramatic swelling of the neck - ANSWER: Diphtheria
Whitish-gray pseudomembrane on the tonsils, throat, or nasal cavity - ANSWER:
Diphtheria
Heart, kidney failure, and paralysis (nerve damage) may occur due to toxin in blood -
ANSWER: Diphtheria
Toxin in lysogenized strains - ANSWER: Corynebacterium diphtheriae
Structure made of dead cells, clotted blood, fibrin, and leukocytes - ANSWER:
Diphtheria Pseudomembrane
Structure that may come loose and obstruct passageway - ANSWER: Diphtheria
Pseudomembrane
Obstruction by a membrane that leads to suffocation - ANSWER: Diphtheria
