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TEST BANK FOR MODERN BLOOD BANKING & TRANSFUSION
PRACTICES 6TH EDITION DENISE M. HARMENING - ( All
Chapters) Latest 2024
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
Multiple Choice
Identify the choice that best completes the statement or answers the question.
____ 1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
a. Pentose phosphate shunt
b. Luebering-Rapoport shunt
c. Glycolysis
d. Methemoglobin reductase
____ 2. A unit of blood was returned to the blood bank before it was spiked. Apparently the
patient’s IV failed. The unit of blood was outside the blood bank for 35 minutes. Which of the
statements below is most accurate?
a. The unit of blood should be discarded immediately.
b. The unit of blood can be returned to inventory.
c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
d. The unit of blood must be transfused with 24 hours.
____ 3. What is the average diameter of a platelet?
a. 5 to 10 µm
b. 2 to 4 µm
c. 1 to 2 µm
d. 4 to 6 µm
____ 4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is
released to the tissues when PO2 averages 40 mm Hg?
a. 75%
b. 25%
c. 100%
d. 50%
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____ 5. What factors are known to influence platelet metabolism and function?
a. Storage temperature
b. Initial pH
c. Platelet count
d. All of the above
____ 6. Which of the following red blood cell morphologies may be present on the peripheral
blood smear as a result of loss of RBC membrane?
a. Spherocytes
b. Target cells
c. Burr cells
d. Schistocytes
____ 7. What does the term autologous transfusion refer to?
a. A parent donating blood for his or her child
b. An individual donating blood for a friend
c. An individual donating blood for a relative
d. An individual donating blood for his or her own transfusion
____ 8. What is the primary function of hemoglobin?
a. Iron metabolism
b. Porphyrin synthesis
c. Oxygen transport
d. Signal transduction
____ 9. All of the following areas of red blood cell biology are crucial for normal erythrocyte
survival except:
a. Cellular metabolism.
b. RBC membrane.
c. Site of the ABO antigen attachment.
d. Hemoglobin structure.
What is the correct biochemical composition of the RBC membrane?
a. 52% protein, 40% lipid, 8% carbohydrate
b. 40% protein, 8% lipid, 52% carbohydrate
c. 8% protein, 52% lipid, 40% carbohydrate
d. 8% lipid, 40% carbohydrate, 52% protein
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____ 11. All of the following biochemical changes are associated with loss of red blood cell
viability upon storage except:
b. Loss of red blood cell function.
a. Decreased pH.
c. Increased ATP level.
d. Decreased glucose consumption.
____ 12. Which red blood cell preservative has a storage time of 35 days?
a. ACD
b. CPDA-1
c. AS-1
d. CPD
____ 13. The RBC membrane is relatively permeable to all of the following except:
a. Chloride.
b. Sodium.
c. Bicarbonate.
d. Water.
____ 14. What percentage of platelets is sequestered in the spleen as functional reserve after
being released from the bone marrow?
a. 30%
b. 50%
c. 10%
d. 25%
____ 15. What is the major biochemical consideration in platelet storage?
a. Glucose metabolism
b. Oxygen supply
c. Production of carbon dioxide
d. Regulation of pH
____ 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting
clinical signs of alkalosis?
a. Normal
b. Shift to the left
c. Shift to the right
d. None of the above
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____ 17. Name the main lipid components of a red blood cell membrane.
a. Phospholipid
b. Sphingomyelin
c. Glycolipid
d. Glycophorin A
____ 18. The ABO blood groups were discovered in 1901 by whom?
a. Charles Drew
b. Karl Landsteiner
c. Loutit and Mollison
d. Edward Lindeman
____ 19. A standing order of platelets was shipped to your facility by your supplier. It was
inadvertently left in the corner of the department until discovered 36 hours later. What would the
appropriate action be for the blood banker?
a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would be OK
to accept the unit into inventory.
b. The platelets have fallen outside the supplier’s quality assurance. The unit should be discarded
because the pH has probably dropped too low and platelet activation has been compromised.
c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to accept
the unit into inventory.
d. If the platelets appeared OK and passed the platelet swirl test after being placed on the
agitator, they could be accepted into the inventory.
____ 20. Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate
(2,3-DPG)?
a. Glycolysis
b. Luebering-Rapoport shunt
c. Pentose phosphate shunt
d. Methemoglobin reductase
____ 21. All of the following are consistent with a "shift to the right" of the hemoglobin-oxygen
dissociation curve except:
a. Increased 2,3-DPG.
b. 50% O2 saturation to tissues.
c. Decreased 2,3-DPG.
d. Decreased hemoglobin affinity for O2.
TestBank A++
PAGE 4
TEST BANK FOR MODERN BLOOD BANKING & TRANSFUSION
PRACTICES 6TH EDITION DENISE M. HARMENING - ( All
Chapters) Latest 2024
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
Multiple Choice
Identify the choice that best completes the statement or answers the question.
____ 1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
a. Pentose phosphate shunt
b. Luebering-Rapoport shunt
c. Glycolysis
d. Methemoglobin reductase
____ 2. A unit of blood was returned to the blood bank before it was spiked. Apparently the
patient’s IV failed. The unit of blood was outside the blood bank for 35 minutes. Which of the
statements below is most accurate?
a. The unit of blood should be discarded immediately.
b. The unit of blood can be returned to inventory.
c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
d. The unit of blood must be transfused with 24 hours.
____ 3. What is the average diameter of a platelet?
a. 5 to 10 µm
b. 2 to 4 µm
c. 1 to 2 µm
d. 4 to 6 µm
____ 4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is
released to the tissues when PO2 averages 40 mm Hg?
a. 75%
b. 25%
c. 100%
d. 50%
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____ 5. What factors are known to influence platelet metabolism and function?
a. Storage temperature
b. Initial pH
c. Platelet count
d. All of the above
____ 6. Which of the following red blood cell morphologies may be present on the peripheral
blood smear as a result of loss of RBC membrane?
a. Spherocytes
b. Target cells
c. Burr cells
d. Schistocytes
____ 7. What does the term autologous transfusion refer to?
a. A parent donating blood for his or her child
b. An individual donating blood for a friend
c. An individual donating blood for a relative
d. An individual donating blood for his or her own transfusion
____ 8. What is the primary function of hemoglobin?
a. Iron metabolism
b. Porphyrin synthesis
c. Oxygen transport
d. Signal transduction
____ 9. All of the following areas of red blood cell biology are crucial for normal erythrocyte
survival except:
a. Cellular metabolism.
b. RBC membrane.
c. Site of the ABO antigen attachment.
d. Hemoglobin structure.
What is the correct biochemical composition of the RBC membrane?
a. 52% protein, 40% lipid, 8% carbohydrate
b. 40% protein, 8% lipid, 52% carbohydrate
c. 8% protein, 52% lipid, 40% carbohydrate
d. 8% lipid, 40% carbohydrate, 52% protein
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____ 11. All of the following biochemical changes are associated with loss of red blood cell
viability upon storage except:
b. Loss of red blood cell function.
a. Decreased pH.
c. Increased ATP level.
d. Decreased glucose consumption.
____ 12. Which red blood cell preservative has a storage time of 35 days?
a. ACD
b. CPDA-1
c. AS-1
d. CPD
____ 13. The RBC membrane is relatively permeable to all of the following except:
a. Chloride.
b. Sodium.
c. Bicarbonate.
d. Water.
____ 14. What percentage of platelets is sequestered in the spleen as functional reserve after
being released from the bone marrow?
a. 30%
b. 50%
c. 10%
d. 25%
____ 15. What is the major biochemical consideration in platelet storage?
a. Glucose metabolism
b. Oxygen supply
c. Production of carbon dioxide
d. Regulation of pH
____ 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting
clinical signs of alkalosis?
a. Normal
b. Shift to the left
c. Shift to the right
d. None of the above
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____ 17. Name the main lipid components of a red blood cell membrane.
a. Phospholipid
b. Sphingomyelin
c. Glycolipid
d. Glycophorin A
____ 18. The ABO blood groups were discovered in 1901 by whom?
a. Charles Drew
b. Karl Landsteiner
c. Loutit and Mollison
d. Edward Lindeman
____ 19. A standing order of platelets was shipped to your facility by your supplier. It was
inadvertently left in the corner of the department until discovered 36 hours later. What would the
appropriate action be for the blood banker?
a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would be OK
to accept the unit into inventory.
b. The platelets have fallen outside the supplier’s quality assurance. The unit should be discarded
because the pH has probably dropped too low and platelet activation has been compromised.
c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to accept
the unit into inventory.
d. If the platelets appeared OK and passed the platelet swirl test after being placed on the
agitator, they could be accepted into the inventory.
____ 20. Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate
(2,3-DPG)?
a. Glycolysis
b. Luebering-Rapoport shunt
c. Pentose phosphate shunt
d. Methemoglobin reductase
____ 21. All of the following are consistent with a "shift to the right" of the hemoglobin-oxygen
dissociation curve except:
a. Increased 2,3-DPG.
b. 50% O2 saturation to tissues.
c. Decreased 2,3-DPG.
d. Decreased hemoglobin affinity for O2.
TestBank A++
PAGE 4
