QUESTIONS AND ANSWERS WITH
SOLUTIONS 2024
TwoQfactorsQthatQdetermineQaQperson'sQbloodQpressureQ-
QANSWERQCardiacQOutputQandQSystemicQVascularQResistance
CardiacQoutputQ-
QANSWERQamountQofQbloodQejectedQfromQtheQheart'sQleftQventricleQinQoneQminuteQ(heartQrateQxQstrokeQv
olume)
SVRQ(systemicQvascularQresistance)Q-QANSWERQamountQofQresistanceQtoQbloodQflow
ContributingQfactorsQtoQaQpatient'sQbloodQpressureQ-QANSWERQCardiacQFactors:QheartQrate,Qcontractibility
CirculatingQVolume:Qsalt,Qalaosterone,Qhormones,QandQperipheralQsympatheticQreceptors
HypertensionQClassificationQ-QANSWERQNormotensiveQ=Q<120/80
PrehypertensiveQ=Q120-139/80-89
HypertensiveQ=Q>140/90
StageQ1Q=Q140-159/90-99
StageQ2Q=Q>160/100
HowQtoQtakeQbloodQpressureQ-
QANSWERQTheQinstrumentQusedQisQcalledQaQsphygmomanometer.QTheQhealthQcareQproviderQusesQaQbloodQ
pressureQcuffQtoQcutQoffQtheQbloodQflowQfromQtheQbrachialQartery.QAsQtheyQreleaseQtheQpressureQinQtheQcu
ff,QusingQaQstethoscope,QtheyQareQlisteningQforQtheQfirstQsound,QcalledQtheQKorotkoffQsound,QmeaningQther
eQisQnoQlongerQenoughQpressureQtoQkeepQallQtheQbloodQfromQflowing.QThisQisQtheQtopQnumberQorQsystolicQ
valueQofQtheQpatient'sQbloodQpressure.QTheQproviderQcontinuesQtoQletQairQoutQofQtheQcuffQandQeventuallyQt
heQsoundsQdisappear,QrepresentingQthatQtheQbrachialQarteryQisQnowQcompletelyQopen.QThisQisQknownQasQt
heQdiastolicQvalueQorQbottomQnumberQinQaQpatient'sQbloodQpressure.
DifferentiateQessentialQhypertensionQandQsecondaryQhypertensionQ-QANSWERQ-
EssentialQhypertensionQ(primaryQhypertension):QcauseQofQtheQincreasedQbloodQpressureQisQunknown.Q
, -SecondaryQhypertension:QelevatedQbloodQpressureQisQcausedQbyQanotherQdisease.
peripheralQresistanceQ-
QANSWERQresistanceQgeneratedQbyQtheQflowQofQbloodQthroughQtheQarteries.QWhenQthisQhappens,QtheQkid
neyQreleasesQanQenzymeQcalledQrenin.
ReninQenzymeQ-
QANSWERQleadsQtoQfurtherQvasoconstriction,QwaterQandQsodiumQretention,QandQanQincreaseQinQbloodQpre
ssure
WhatQhappensQtoQtheQperipheralQresistanceQduringQhighQbloodQpressureQ-
QANSWERQthereQisQanQincreasedQperipheralQresistanceQwhichQdecreasesQbloodQsupplyQtoQtheQkidney.
AntihypertensiveQtherapyQ-QANSWERQ-
goalQisQtoQdecreaseQmorbidityQandQmortalityQwithoutQdecreasingQqualityQofQlife
AntihypertensiveQtherapyQshouldQbeQstartedQinQpatientsQ-
QANSWERQ·Q60+QifQtheirQbloodQpressureQ>150/90mm/Hg.
·Q59-QorQthoseQwithQchronicQkidneyQdiseaseQorQdiabetesQusedQwhenQtheQbloodQpressureQ>140/90mm/Hg.
TheQfourQfirstQlineQantihypertensivesQ-QANSWERQ-ThiazideQdiuretics
-ACE-Inhibitors
-ARBs
-CCBs
ThiazideQDiureticsQ(mechanismQofQactionQ&Qexample)Q-QANSWERQ-QknownQasQaQlowQsodiumQdiet
-
QdecreasesQplasmaQandQextracellularQfluidQvolumesQwhichQdecreasesQpreloadQandQleadsQtoQaQdecreaseQin
QcardiacQoutputQandQtotalQperipheralQresistance.
-QHydrochlorothiazide