SBB Genetic, Rh and
RBC Membrane Exam
2024 Update
The 1980s - ✔✔✔ANSWER-What decade was the start of Rh molecular biology
and purification of Rh D polypeptides
The 1990s - ✔✔✔ANSWER-What decade started the cloning of Rh genes and
molecular bases of D+ and D -phenotypes
, 1 ml of Rh positive cells can stimulate antibody production in an Rh negative
person - ✔✔✔ANSWER-____________ ml of Rh positive cells can stimulate
antibody production in an Rh negative person
1 to 2% - ✔✔✔ANSWER-It has been shown that______________ of individuals
with European ancestry posses some altered form of D antigen
But occurs more in African descent
275 RHD alleles and 50 RHCE have been documented - ✔✔✔ANSWER-Since the
begining of molecular,
How many RHD and RHCE genes have been discovered ?
5' to 3' - ✔✔✔ANSWER-Transcripts are single stranded RNA copies of DNA that
run in which prime directions?
700 series Low's = < 1% of most population studied and or not known to belong to
a blood group system
901 series occurs in
> 90% of populations and are not known to belong to a blood group system -
✔✔✔ANSWER-Explain the 700 and 901 series
97% identical and
32 to 35 different amino acids - ✔✔✔ANSWER-RHD and RHCE genes are
_______% identical
And __________ different amino acids
accepted - ✔✔✔ANSWER-The terminology of Du is no longer
RBC Membrane Exam
2024 Update
The 1980s - ✔✔✔ANSWER-What decade was the start of Rh molecular biology
and purification of Rh D polypeptides
The 1990s - ✔✔✔ANSWER-What decade started the cloning of Rh genes and
molecular bases of D+ and D -phenotypes
, 1 ml of Rh positive cells can stimulate antibody production in an Rh negative
person - ✔✔✔ANSWER-____________ ml of Rh positive cells can stimulate
antibody production in an Rh negative person
1 to 2% - ✔✔✔ANSWER-It has been shown that______________ of individuals
with European ancestry posses some altered form of D antigen
But occurs more in African descent
275 RHD alleles and 50 RHCE have been documented - ✔✔✔ANSWER-Since the
begining of molecular,
How many RHD and RHCE genes have been discovered ?
5' to 3' - ✔✔✔ANSWER-Transcripts are single stranded RNA copies of DNA that
run in which prime directions?
700 series Low's = < 1% of most population studied and or not known to belong to
a blood group system
901 series occurs in
> 90% of populations and are not known to belong to a blood group system -
✔✔✔ANSWER-Explain the 700 and 901 series
97% identical and
32 to 35 different amino acids - ✔✔✔ANSWER-RHD and RHCE genes are
_______% identical
And __________ different amino acids
accepted - ✔✔✔ANSWER-The terminology of Du is no longer
