PHCY 502_ Week 13_ Liver and Renal
Induced Disease
Afferent - answer✔the vessel supplying the glomerulus of the nephron with blood
Efferent - answer✔the blood vessel leaving the glomerulus of the nephron, which transports
filtered blood back into circulation
Acute Kidney Injury (AKI) - answer✔a sudden failure of the kidney to filter blood, denoted by
a rapid increase in serum creatinine.
Autoregulation - answer✔the process by which a body system adapts to certain stimuli (ex.
Activation of RAAS in response to low perfusion of the kidneys, such as due to low blood
pressure)
Nephrolithiasis - answer✔kidney stones
Natriuresis - answer✔excretion of sodium in the urine
Anuria - answer✔failure to produce urine
Oliguria - answer✔the production of abnormally small amounts of urine
Non-oliguria - answer✔a term used to describe a kidney injury that does not result in an
abnormally low production of urine
Asterixis - answer✔"hand-flapping" which is an indicator of liver failure
Bilirubin - answer✔a substance formed from the breakdown of hemoglobin, which is excreted
in bile
Cirrhosis - answer✔a disease of the liver marked by hepatocellular damage, inflammation
causing cholestasis, and fibrosis of tissue
Conjugated Bilirubin - answer✔bilirubin that has been processed (conjugated) by the liver.
Also called "direct" bilirubin
Conjugation - answer✔the process by which the liver processes bilirubin (involves disruption
of hydrogen bonds)