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Pmcol 305 Amphetamines Exam Questions With Correct Answers

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©THEBRIGHTSTARS 2024 Pmcol 305 Amphetamines Exam Questions With Correct Answers From what is amphetamine derived from - answerChinese medicinal herb called Ma Huang or Ephedra Sinica Who was the first to synthesize AMPH - answerLazar Edeleano made alpha methylphenethylamine in 1887 to treat athsma L-Amphetamine - answerInto pageR, aises BP, Nasal passages open and headache D-Amphetamine - answerSame as L but added mood enhancement and enhances energy Methamphetamine - answerIncreased lipid solubility causes increase potency and brain effects Most potent amphetamine - answerMeth least potent amphetamine - answerL-Amphetamine 3 Ways to make methamphetamines - answerNagai synthesis- Pseudoephedrine/ephedrine+Acid and red phosphorus Reductive Amination Phenylacetone+Methyl amine Leuckart Synthesis Phenylacetone + N-methylformamide Amphetamines are structurally close to.. - answerCatecholamines Why is Meth the drug of choice - answerExtra methyl group, Slower metabolism, CNS effects are stronger, Smokeable and cheaper Absorption of Amphetamines - answer(fastest onset) Smoked (70%), Injected, snorted(80) or ingested (70-99%) (Slowest onse

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©THEBRIGHTSTARS 2024


Pmcol 305 Amphetamines Exam Questions
With Correct Answers


From what is amphetamine derived from - answer✔Chinese medicinal herb called Ma Huang
or Ephedra Sinica

Who was the first to synthesize AMPH - answer✔Lazar Edeleano made alpha
methylphenethylamine in 1887 to treat athsma

L-Amphetamine - answer✔Into pageR, aises BP, Nasal passages open and headache

D-Amphetamine - answer✔Same as L but added mood enhancement and enhances energy

Methamphetamine - answer✔Increased lipid solubility causes increase potency and brain
effects

Most potent amphetamine - answer✔Meth

least potent amphetamine - answer✔L-Amphetamine

3 Ways to make methamphetamines - answer✔Nagai synthesis-
Pseudoephedrine/ephedrine+Acid and red phosphorus


Reductive Amination
Phenylacetone+Methyl amine


Leuckart Synthesis
Phenylacetone + N-methylformamide

Amphetamines are structurally close to.. - answer✔Catecholamines

Why is Meth the drug of choice - answer✔Extra methyl group, Slower metabolism, CNS
effects are stronger, Smokeable and cheaper

Absorption of Amphetamines - answer✔(fastest onset) Smoked (70%), Injected, snorted(80) or
ingested (70-99%) (Slowest onset)
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