CMN 568 UNIT 3 TEST QUESTIONS
WITH ALL ANSWERS REVISED
AND UPDATED
What percentage of people with normal immunity will develop TB disease after being
infected? - Answer-10%
What is the highest risk factor of developing TB disease? - Answer-HIV and children <5
What two tests are used to detect TB? - Answer-Mantoux TB skin test and IGRAs (TB
spot and Quantiferon Gold)
What is considered a wheal or raised area in a ppd test? - Answer-6-10mm
A > or = to induration of 5mm on a ppd test is positive for who? - Answer-HIV, recent
contacts of infectious TB, People with fibrotic changes on a chest x-ray consistent with
prior TB, or organ transplant recipients and immunocompromised
A > or = to induration of 10mm on a ppd test is positive for who? - Answer-Recent travel
to prevalent countries, injection drug users, residents and employees of high risk
congregate settings (myobacterial lab personnel), immunocompromised, children < 5 or
children exposed to adults at high risk
A > or = induration of 15mm on a ppd test is positive for who? - Answer-All persons with
no known risk factors
Why is a 2-step TB test given? - Answer-Used for initial skin test of adults that will be
retested periodically, to reduce the likelihood that a boosted reaction will be
misinterpretated as a recent infection
Is TST safe during pregnancy? - Answer-yes
When should IGRA tb testing be done? - Answer-In place of, but not in addition to TST
testing when concern for pt. returning to have TST read. Not for children <5 unless in
conjunction with TST
What are the symptoms of pulmonary TB? - Answer-cough > 3 weeks, hemoptysis,
chest pain, weight loss, night sweats, fever, fatigue
, What should be tested in any person suspected of having TB? How should specimens
be obtained? - Answer-sputum cx; 3 different specimens atleast 8 hours apart, one of
which should be first thing in the morning
What is the gold standard for diagnosing TB? - Answer-sputum culture
What is the treatment of choice for LTBI? - Answer-Isoniazid 9 month daily regimen
What is the preferred medication for children ages 2-11 with LTBI? - Answer-Isoniazid
What are some serious adverse effects of Isoniazid? - Answer-peripheral neuropathy,
fatal hepatitis, and elevated liver enzymes
What medication should be offered to patients with TB disease, but NOT for LTBI? -
Answer-pyrazinamide
What are the four first-line drugs to treat TB disease? - Answer-Isoniziad, Rifampin,
Pyrazinamide, ethambutol
What serious side effects are associated with LTRAs in asthma treatment? - Answer-
anxiety, depression, and suicidal ideations
What patient education should be included on patients taking LTRAs? - Answer-take on
empty stomach and it will take 1-2 weeks for therapeutic response is reached
What is the "booster phenomenon"? - Answer-When someone (e.g. older person) is
infected with TB, but initially tests negative, then on subsequent tests, tests positive.
The initial test "boosts" their immune response.
How can vocal cord dysfunction be distuinguished from asthma or EIB? - Answer-
response to bronchodilators, normal spirometry immediately after an attack, spirometric
evidence of upper airway, negative bronchial provocation test, or direct visualization of
vocal cord adduction on both inspiration and expiration
How is vocal cord dysfunction treated? - Answer-speech therapy, breathing, voice, and
neck relaxation exercises.
What is the strongest identifiable predisposing factor for the development of asthma?
What is becoming increasingly recognizable as a significant risk factor? - Answer-atopy
(tendency to be hyperallergic); obesity
What is considered a late asthmatic response? - Answer-4-6 hours after exposure to
allergen
What are the most common allergens? - Answer-dust mites, cockroaches, cat dander,
and seasonal pollens
WITH ALL ANSWERS REVISED
AND UPDATED
What percentage of people with normal immunity will develop TB disease after being
infected? - Answer-10%
What is the highest risk factor of developing TB disease? - Answer-HIV and children <5
What two tests are used to detect TB? - Answer-Mantoux TB skin test and IGRAs (TB
spot and Quantiferon Gold)
What is considered a wheal or raised area in a ppd test? - Answer-6-10mm
A > or = to induration of 5mm on a ppd test is positive for who? - Answer-HIV, recent
contacts of infectious TB, People with fibrotic changes on a chest x-ray consistent with
prior TB, or organ transplant recipients and immunocompromised
A > or = to induration of 10mm on a ppd test is positive for who? - Answer-Recent travel
to prevalent countries, injection drug users, residents and employees of high risk
congregate settings (myobacterial lab personnel), immunocompromised, children < 5 or
children exposed to adults at high risk
A > or = induration of 15mm on a ppd test is positive for who? - Answer-All persons with
no known risk factors
Why is a 2-step TB test given? - Answer-Used for initial skin test of adults that will be
retested periodically, to reduce the likelihood that a boosted reaction will be
misinterpretated as a recent infection
Is TST safe during pregnancy? - Answer-yes
When should IGRA tb testing be done? - Answer-In place of, but not in addition to TST
testing when concern for pt. returning to have TST read. Not for children <5 unless in
conjunction with TST
What are the symptoms of pulmonary TB? - Answer-cough > 3 weeks, hemoptysis,
chest pain, weight loss, night sweats, fever, fatigue
, What should be tested in any person suspected of having TB? How should specimens
be obtained? - Answer-sputum cx; 3 different specimens atleast 8 hours apart, one of
which should be first thing in the morning
What is the gold standard for diagnosing TB? - Answer-sputum culture
What is the treatment of choice for LTBI? - Answer-Isoniazid 9 month daily regimen
What is the preferred medication for children ages 2-11 with LTBI? - Answer-Isoniazid
What are some serious adverse effects of Isoniazid? - Answer-peripheral neuropathy,
fatal hepatitis, and elevated liver enzymes
What medication should be offered to patients with TB disease, but NOT for LTBI? -
Answer-pyrazinamide
What are the four first-line drugs to treat TB disease? - Answer-Isoniziad, Rifampin,
Pyrazinamide, ethambutol
What serious side effects are associated with LTRAs in asthma treatment? - Answer-
anxiety, depression, and suicidal ideations
What patient education should be included on patients taking LTRAs? - Answer-take on
empty stomach and it will take 1-2 weeks for therapeutic response is reached
What is the "booster phenomenon"? - Answer-When someone (e.g. older person) is
infected with TB, but initially tests negative, then on subsequent tests, tests positive.
The initial test "boosts" their immune response.
How can vocal cord dysfunction be distuinguished from asthma or EIB? - Answer-
response to bronchodilators, normal spirometry immediately after an attack, spirometric
evidence of upper airway, negative bronchial provocation test, or direct visualization of
vocal cord adduction on both inspiration and expiration
How is vocal cord dysfunction treated? - Answer-speech therapy, breathing, voice, and
neck relaxation exercises.
What is the strongest identifiable predisposing factor for the development of asthma?
What is becoming increasingly recognizable as a significant risk factor? - Answer-atopy
(tendency to be hyperallergic); obesity
What is considered a late asthmatic response? - Answer-4-6 hours after exposure to
allergen
What are the most common allergens? - Answer-dust mites, cockroaches, cat dander,
and seasonal pollens
