BIOS 390- Unit 3 Receptors-Questions and Answers
100% Solved
What are the 2 requirements for hormone responsiveness? Correct Ans-hormone is
available and there are receptors
What is the first order receptor? Correct Ans-the receptor that the hormone binds to
What are the two ways hormones can be secreted with regard to synthesis? Correct Ans--
independent of synthesis
- directly coupled to synthesis
What does it mean if you upregulate the synthesis of a hormone and see no change in
secretion? Correct Ans-secretion is independent of synthesis
Which type of hormones is stored in the cells in large quantities? Correct Ans-peptide and
protein hormones
Which type of hormone has secretion directly coupled to synthesis? Correct Ans-steroids
(they are produced as needed)
, BIOS 390- Unit 3 Receptors-Questions and Answers
100% Solved
What occurs in a free standing gland/cell? Correct Ans-responds to a variety of signals
which can increase or decrease synthesis or secretion of the hormone
What is negative feedback loop with hormone secretion in a free standing gland/cell?
Correct Ans-as hormone secretion increases the hormone itself or the biological response
by the target cells may negatively feedback on the gland to decrease its own secretion
What are the major endocrine glands regulated by ? Correct Ans-pituitary tropic hormones
The pituitary tropic hormones are in turn regulated by what? Correct Ans-releasing
hormones from the hypothalamus in the brain
Where is the pituitary tropic hormones potential for negative feedback? Correct Ans-at
each part of the hypothalamic-pituitary axis
How are peptide/protein hormones transported? Correct Ans-they are soluble so they
circulate in the aqueous serum without assistance
, BIOS 390- Unit 3 Receptors-Questions and Answers
100% Solved
How are steroid and thyroid hormones transported? Correct Ans-bound to plasma
proteins because they are not soluble in water
What happens if the hydrophobic hormones do not have transporting proteins? Correct
Ans-they will not be uniformly distributed in the body, rather they will localize in nearby cells
What is the free hormone hypothesis (3)? Correct Ans-- unbound (free) steroid and TH in
the serum can readily enter the cell
- hormone in cytoplasm is at equilibrium with the free hormone in the blood
- hormones simply diffuse into the cell
Why is the free hormone hypothesis wrong? Correct Ans-transport proteins play a critical
role in steroid and TH uptake, and free hormones in the blood and cytoplasm are not
necessarily at equilibrium
What is the more common name for binding proteins? Correct Ans-distributing proteins
100% Solved
What are the 2 requirements for hormone responsiveness? Correct Ans-hormone is
available and there are receptors
What is the first order receptor? Correct Ans-the receptor that the hormone binds to
What are the two ways hormones can be secreted with regard to synthesis? Correct Ans--
independent of synthesis
- directly coupled to synthesis
What does it mean if you upregulate the synthesis of a hormone and see no change in
secretion? Correct Ans-secretion is independent of synthesis
Which type of hormones is stored in the cells in large quantities? Correct Ans-peptide and
protein hormones
Which type of hormone has secretion directly coupled to synthesis? Correct Ans-steroids
(they are produced as needed)
, BIOS 390- Unit 3 Receptors-Questions and Answers
100% Solved
What occurs in a free standing gland/cell? Correct Ans-responds to a variety of signals
which can increase or decrease synthesis or secretion of the hormone
What is negative feedback loop with hormone secretion in a free standing gland/cell?
Correct Ans-as hormone secretion increases the hormone itself or the biological response
by the target cells may negatively feedback on the gland to decrease its own secretion
What are the major endocrine glands regulated by ? Correct Ans-pituitary tropic hormones
The pituitary tropic hormones are in turn regulated by what? Correct Ans-releasing
hormones from the hypothalamus in the brain
Where is the pituitary tropic hormones potential for negative feedback? Correct Ans-at
each part of the hypothalamic-pituitary axis
How are peptide/protein hormones transported? Correct Ans-they are soluble so they
circulate in the aqueous serum without assistance
, BIOS 390- Unit 3 Receptors-Questions and Answers
100% Solved
How are steroid and thyroid hormones transported? Correct Ans-bound to plasma
proteins because they are not soluble in water
What happens if the hydrophobic hormones do not have transporting proteins? Correct
Ans-they will not be uniformly distributed in the body, rather they will localize in nearby cells
What is the free hormone hypothesis (3)? Correct Ans-- unbound (free) steroid and TH in
the serum can readily enter the cell
- hormone in cytoplasm is at equilibrium with the free hormone in the blood
- hormones simply diffuse into the cell
Why is the free hormone hypothesis wrong? Correct Ans-transport proteins play a critical
role in steroid and TH uptake, and free hormones in the blood and cytoplasm are not
necessarily at equilibrium
What is the more common name for binding proteins? Correct Ans-distributing proteins
