WITH CORRECT ANSWERS
Drug therapy for both asthma and COPD - CORRECT-
ANSWERSBronchodilation (historically) and anti-inflammatory (more recently
popular) and are often used in combination
Bronchodilation - CORRECT-ANSWERSinclude medications that improve
airflow by relaxing smooth muscle cells in bronchials, leading to dilation and
increased airflow.
Anti-inflammatory - CORRECT-ANSWERS- Inhaled corticosteroids (ICS),
Leukotriene Inhibitors
- "controller" drugs because they reduce and control the inflammatory
response.
- When inflammatory response is under control, bronchodilator drugs can
work more effectively.
three types of bronchodilators - CORRECT-ANSWERSbeta adrenergic
agonists, anticholinergic, and theophylline.
Beta adrenergic agonists mechanism of action - CORRECT-ANSWERSrelax
and dilate the airways by stimulating the beta2 adrenergic receptors within
the lungs.
Anticholinergic mechanism of action - CORRECT-ANSWERSby blocking effects
of acetylcholine these drugs can produce bronchodilation and reduce volume
of respiratory secretions.
Theophylline mechanism of action - CORRECT-ANSWERSinhibits the enzyme
phosphodiesterase.
*This enzyme is known to inactivate a compound called cyclic adenosine
monophosphate (cAMP) that leads to bronchodilation.
two classes of drugs for anti-inflammatory respiratory medications -
CORRECT-ANSWERS-Corticosteroids
-Leukotriene receptor antagonists
Inhaled Corticosteroids (ICS) - CORRECT-ANSWERS- The exact mechanism of
action is unknown.