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NURSING PHARMACOLOGY 8TH EDITION
Blood dyscrasia
Bone marrow depression caused by drug effects on the rapidly multiplying cells of the bone marrow; lower-
than-normal levels of blood components can be seen
Dermatological reactions
skin reactions commonly seen as adverse effects of drugs; can range from simple rash to potentially fatal
exfoliative dermatitis
Drug allergy
formation of antibodies to a drug or drug protein; causes an immune response when the person is next
exposed to that drug
Hypersensitivity
excessive responsiveness to either the primary or the secondary effects of a drug; may be caused by a
pathological condition or, in the absence of one, by a particular patient's individual response
Poisoning
overdose of a drug that causes damage to multiple body systems and has the potential of fatal reaction
Stomatitis
inflammation of the mucus membranes related to drug effects; can lead to alteration of nutrition and dental
problems
Superinfections
infections caused by the destruction of normal flora bacteria by certain drugs; which allow other bacteria to
grow out of control and cause infections; may occur during the course of antibiotic therapy
Adverse Effects
Adverse effects are undesired effects that may be unpleasant or even dangerous. The y may occur for many
reasons including:
1) the drug may have other effects on the body besides the therapeutic effect.
2)The patient may be sensitive to the drug being given
3)The drugs action on the body may cause other responses that are undesirable or unpleasant
4)The patient may be taking too much or too little of the drug, leading to adverse effects
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