TEST BANK
15th Edition Basic and Clinical
Pharmacology Test Bank with
questions and answers
1. The patient asks the nurse, Is it safe to take over-the-counter (OTC)
. medications with prescription medications? What is the nurses best
response? (Select all that apply.)
A) OTC medications can interact with prescription medications.
B) It is important to tell your doctor all medications you take, including
OTC.
C) OTC medications could mask or hide signs and symptoms of a disease.
D) You should avoid taking any OTC medication when taking prescription
drugs.
E) Taking OTC medications can make your prescription medication more
effective.
Ans: A, B, C
Feedback:
OTC medications can interact with prescription medications or other OTC so
it is always important to consult your pharmacist and provider for advice. To
provide the most accurate instruction, the health care provider must know all
medications taken including dietary supplements, OTC, and prescription.
OTC medications could mask or hide symptoms of a disease so it is always
important to consult a physician if symptoms persist. OTC medications are
not prohibited when taking prescription drugs as long as no drug interaction
occurs. How an OTC will impact a prescription medication varies depending
on the medications involved, so it is incorrect to say it will make the
prescription drug more effective.
,2. Before administering a prescription medication, what information does the
. nurse find on the drug label? (Select all that apply.)
A) Brand name
B) Generic name
C) Drug concentration
D) Expiration date
E) Adverse effects
Ans: A, B, C, D
, Feedback:
Prescription drug labels will contain the brand name, generic name, drug
concentration, and expiration date. Adverse effects will not be listed on drug
labels.
3. The nurse is preparing a medication that is new to the market and cannot be
. found in the nurses drug guide. Where can the nurse get the most reliable
information about this medication?
A) Package insert
B) Another nurse
C) Drug manufacturer
D) Physician
Ans: A
Feedback:
The most reliable information about the drug can be found on the package
insert supplied by the manufacturer because it was prepared according to
strict Food and Drug Administration (FDA) regulations. Asking another
nurse or the physician is not reliable and cannot be verified as accurate. It
would not be realistic to call the drug manufacturer for information.
4. The nurse explains that what drug resource book is compiled from package
. inserts?
A) Nurses Drug Guide
B) Physiciass Desk Reference (PDR)
C) Drug Facts and Comparisons
D) AMA Drug Evaluations
Ans: B
Feedback:
, The PDR is a compilation of information found on package inserts.
The Nurses Drug Guide uses more easily understood language and
incorporates nursing considerations and patient teaching points. Drug Facts
and Comparisons includes cost comparison, often not found in other drug
resource guides. The AMA Drug Evaluations is far less biased than the PDR
and includes drugs still in the research stage of development.
Chapter 2- Chapter 5 Drug Receptors & Pharmacodynamics
Chapter 3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of
Drug Action Chapter 4. Drug Biotransformation Chapter 5. Pharmacogenomics
1. Drugs do not metabolize the same way in all people. For what patient would
a nurse expect to assess for an alteration in drug metabolism?
A) A 35-year-old woman with cervical cancer
B) A 41-year-old man with kidney stones
C) A 50-year-old man with cirrhosis of the liver
D) A 62-year-old woman in acute renal failure
Ans: C
Feedback:
The liver is the most important site of drug metabolism. If the liver is not
functioning effectively, as in patients with cirrhosis, drugs will not
metabolize normally so that toxic levels could develop unless dosage is
reduced. A patient with cervical cancer or kidney stones would not be
expected to have altered ability to metabolize drugs so long as no liver
damage existed. The patient with renal failure would have altered excretion
of the drugs through the renal system but metabolism would not be impacted.
2. A patient presents to the emergency department with a drug level of 50 units/
mL. The half-life of this drug is 1 hour. With this drug, concentrations above
25 units/mL are considered toxic and no more drug is given. How long will
it take for the blood level to reach the non-toxic range?
A) 30 minutes
B) 1 hour
C) 2 hours
15th Edition Basic and Clinical
Pharmacology Test Bank with
questions and answers
1. The patient asks the nurse, Is it safe to take over-the-counter (OTC)
. medications with prescription medications? What is the nurses best
response? (Select all that apply.)
A) OTC medications can interact with prescription medications.
B) It is important to tell your doctor all medications you take, including
OTC.
C) OTC medications could mask or hide signs and symptoms of a disease.
D) You should avoid taking any OTC medication when taking prescription
drugs.
E) Taking OTC medications can make your prescription medication more
effective.
Ans: A, B, C
Feedback:
OTC medications can interact with prescription medications or other OTC so
it is always important to consult your pharmacist and provider for advice. To
provide the most accurate instruction, the health care provider must know all
medications taken including dietary supplements, OTC, and prescription.
OTC medications could mask or hide symptoms of a disease so it is always
important to consult a physician if symptoms persist. OTC medications are
not prohibited when taking prescription drugs as long as no drug interaction
occurs. How an OTC will impact a prescription medication varies depending
on the medications involved, so it is incorrect to say it will make the
prescription drug more effective.
,2. Before administering a prescription medication, what information does the
. nurse find on the drug label? (Select all that apply.)
A) Brand name
B) Generic name
C) Drug concentration
D) Expiration date
E) Adverse effects
Ans: A, B, C, D
, Feedback:
Prescription drug labels will contain the brand name, generic name, drug
concentration, and expiration date. Adverse effects will not be listed on drug
labels.
3. The nurse is preparing a medication that is new to the market and cannot be
. found in the nurses drug guide. Where can the nurse get the most reliable
information about this medication?
A) Package insert
B) Another nurse
C) Drug manufacturer
D) Physician
Ans: A
Feedback:
The most reliable information about the drug can be found on the package
insert supplied by the manufacturer because it was prepared according to
strict Food and Drug Administration (FDA) regulations. Asking another
nurse or the physician is not reliable and cannot be verified as accurate. It
would not be realistic to call the drug manufacturer for information.
4. The nurse explains that what drug resource book is compiled from package
. inserts?
A) Nurses Drug Guide
B) Physiciass Desk Reference (PDR)
C) Drug Facts and Comparisons
D) AMA Drug Evaluations
Ans: B
Feedback:
, The PDR is a compilation of information found on package inserts.
The Nurses Drug Guide uses more easily understood language and
incorporates nursing considerations and patient teaching points. Drug Facts
and Comparisons includes cost comparison, often not found in other drug
resource guides. The AMA Drug Evaluations is far less biased than the PDR
and includes drugs still in the research stage of development.
Chapter 2- Chapter 5 Drug Receptors & Pharmacodynamics
Chapter 3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of
Drug Action Chapter 4. Drug Biotransformation Chapter 5. Pharmacogenomics
1. Drugs do not metabolize the same way in all people. For what patient would
a nurse expect to assess for an alteration in drug metabolism?
A) A 35-year-old woman with cervical cancer
B) A 41-year-old man with kidney stones
C) A 50-year-old man with cirrhosis of the liver
D) A 62-year-old woman in acute renal failure
Ans: C
Feedback:
The liver is the most important site of drug metabolism. If the liver is not
functioning effectively, as in patients with cirrhosis, drugs will not
metabolize normally so that toxic levels could develop unless dosage is
reduced. A patient with cervical cancer or kidney stones would not be
expected to have altered ability to metabolize drugs so long as no liver
damage existed. The patient with renal failure would have altered excretion
of the drugs through the renal system but metabolism would not be impacted.
2. A patient presents to the emergency department with a drug level of 50 units/
mL. The half-life of this drug is 1 hour. With this drug, concentrations above
25 units/mL are considered toxic and no more drug is given. How long will
it take for the blood level to reach the non-toxic range?
A) 30 minutes
B) 1 hour
C) 2 hours
