NSG 552 PSYCHOPHARMACOLOGY EXAM 3 LATEST
ACTUAL EXAM
Naloxone (Narcan) - ANSWER: opiate antagonist, reverses opioid induced respiratory
depression
Treatment of choice for all patients with opioid use disorder
Very short half-life
What is Methadone also known as? - ANSWER: Dolophine
What type of opioid receptor agonist is Methadone? - ANSWER: Long-acting full
agonist at the mu receptor
How often is Methadone dosed? - ANSWER: Once daily
In what type of programs is Methadone use restricted? - ANSWER: Federally licensed
substance abuse treatment programs
What should be monitored when using Methadone? - ANSWER: QTC prolongation
What is Buprenorphine (Buprenex, Sublocade)? - ANSWER: Partial Opioid receptor
agonist
What is the function of Buprenorphine/Naloxone (Suboxone)? - ANSWER: Opioid
antagonist
What effect does Buprenorphine have on cravings? - ANSWER: Decreases cravings
What precaution is needed when using Suboxone in outpatient settings? - ANSWER:
Waiver needed to prescribe in outpatient settings
What can happen if Buprenorphine is used too soon after a full opioid agonist? -
ANSWER: Can precipitate withdrawal
How does Suboxone interact with residual opioids from mu receptors? - ANSWER: It
will displace any residual opioids from the mu receptors
What is the route of administration for Suboxone? - ANSWER: Sublingual preparation
In what situation can Suboxone be used in managing pain? - ANSWER: Opioid Use
disorder w/ comorbid pain
What type of antagonist is Naltrexone? - ANSWER: Competitive opioid antagonist
, What can happen if Naltrexone is used within 7 days of heroin use? - ANSWER:
Precipitate withdrawal
How is Naltrexone available for use? - ANSWER: Orally or monthly depot injection
When is Naltrexone considered the treatment of choice? - ANSWER: For highly
motivated patients
What is a potential risk associated with Naltrexone use? - ANSWER: Risk for LFT
elevation
Naltrexone - ANSWER: Available PO (Revia) Available IM (Vivitrol)
Buprenorphine (Buprenex, Sublocade) Buprenorphine/Naloxone (Suboxone) -
ANSWER: Suboxone= available Buccal film, sublingual film, sublingual tab
Buprenorphine= Available sublingual tab; subdermal implant, SQ injection
What are the common symptoms of opioid overdose? - ANSWER: Miosis,
Hypotension, Bradycardia, Low RR, Unconsciousness
How is opioid overdose managed? - ANSWER: Naloxone
What are the symptoms of opioid withdrawal? - ANSWER: Anxiety, Lacrimation,
Muscle aches, Abdominal cramps, Diarrhea, Seizures
What medications are used for opioid withdrawal management? - ANSWER:
Buprenorphine/naloxone, Clonidine, Bentyl
In opioid detoxification, which medication is more effective at suppressing
withdrawal symptoms towards the end of the taper? - ANSWER: Buprenorphine
(compared to methadone)
What are some symptoms of cocaine use? - ANSWER: Auditory hallucinations,
agitation, violent behavior, muscle twitching, hypertension, tachycardia
How is lorazepam used in the treatment of cocaine use disorder? - ANSWER: It is
used to treat agitation and muscle twitching associated with cocaine use
How does Antabuse work in the treatment of cocaine use disorder? - ANSWER: It
increases synaptic dopamine in the brain reward circuit and acts as an agonist
treatment
What medications are used for cocaine-induced chest pain and myocardial
infarction? - ANSWER: Nitroglycerin and Aspirin
Why is Metoprolol contraindicated in patients with cocaine-induced chest pain? -
ANSWER: It further lowers coronary blood flow, worsening ischemia
ACTUAL EXAM
Naloxone (Narcan) - ANSWER: opiate antagonist, reverses opioid induced respiratory
depression
Treatment of choice for all patients with opioid use disorder
Very short half-life
What is Methadone also known as? - ANSWER: Dolophine
What type of opioid receptor agonist is Methadone? - ANSWER: Long-acting full
agonist at the mu receptor
How often is Methadone dosed? - ANSWER: Once daily
In what type of programs is Methadone use restricted? - ANSWER: Federally licensed
substance abuse treatment programs
What should be monitored when using Methadone? - ANSWER: QTC prolongation
What is Buprenorphine (Buprenex, Sublocade)? - ANSWER: Partial Opioid receptor
agonist
What is the function of Buprenorphine/Naloxone (Suboxone)? - ANSWER: Opioid
antagonist
What effect does Buprenorphine have on cravings? - ANSWER: Decreases cravings
What precaution is needed when using Suboxone in outpatient settings? - ANSWER:
Waiver needed to prescribe in outpatient settings
What can happen if Buprenorphine is used too soon after a full opioid agonist? -
ANSWER: Can precipitate withdrawal
How does Suboxone interact with residual opioids from mu receptors? - ANSWER: It
will displace any residual opioids from the mu receptors
What is the route of administration for Suboxone? - ANSWER: Sublingual preparation
In what situation can Suboxone be used in managing pain? - ANSWER: Opioid Use
disorder w/ comorbid pain
What type of antagonist is Naltrexone? - ANSWER: Competitive opioid antagonist
, What can happen if Naltrexone is used within 7 days of heroin use? - ANSWER:
Precipitate withdrawal
How is Naltrexone available for use? - ANSWER: Orally or monthly depot injection
When is Naltrexone considered the treatment of choice? - ANSWER: For highly
motivated patients
What is a potential risk associated with Naltrexone use? - ANSWER: Risk for LFT
elevation
Naltrexone - ANSWER: Available PO (Revia) Available IM (Vivitrol)
Buprenorphine (Buprenex, Sublocade) Buprenorphine/Naloxone (Suboxone) -
ANSWER: Suboxone= available Buccal film, sublingual film, sublingual tab
Buprenorphine= Available sublingual tab; subdermal implant, SQ injection
What are the common symptoms of opioid overdose? - ANSWER: Miosis,
Hypotension, Bradycardia, Low RR, Unconsciousness
How is opioid overdose managed? - ANSWER: Naloxone
What are the symptoms of opioid withdrawal? - ANSWER: Anxiety, Lacrimation,
Muscle aches, Abdominal cramps, Diarrhea, Seizures
What medications are used for opioid withdrawal management? - ANSWER:
Buprenorphine/naloxone, Clonidine, Bentyl
In opioid detoxification, which medication is more effective at suppressing
withdrawal symptoms towards the end of the taper? - ANSWER: Buprenorphine
(compared to methadone)
What are some symptoms of cocaine use? - ANSWER: Auditory hallucinations,
agitation, violent behavior, muscle twitching, hypertension, tachycardia
How is lorazepam used in the treatment of cocaine use disorder? - ANSWER: It is
used to treat agitation and muscle twitching associated with cocaine use
How does Antabuse work in the treatment of cocaine use disorder? - ANSWER: It
increases synaptic dopamine in the brain reward circuit and acts as an agonist
treatment
What medications are used for cocaine-induced chest pain and myocardial
infarction? - ANSWER: Nitroglycerin and Aspirin
Why is Metoprolol contraindicated in patients with cocaine-induced chest pain? -
ANSWER: It further lowers coronary blood flow, worsening ischemia
