NURS 8022 EXAM 2

NURS 8022 EXAM 2 LATEST ACTUAL EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |
ALREADY GRADED A+

HEMATOPOIESIS - ANSWER: THE PROCESS OF BLOOD CELL PRODUCTION

WHERE ARE RED BLOOD CELLS MADE? - ANSWER: ADULTS: BONE MARROW
CHILDREN: LIVER AND/OR SPLEEN

WHAT ARE THE TWO STAGES OF HEMATOPOIESIS? - ANSWER: MITOSIS
(PROLIFERATION)
MATURATION (DIFFERENTIATION)

WHERE IS ADULT ACTIVE BONE MARROW FOUND? - ANSWER: PELVIC BONES
VERTEBRAE
CRANIUM
MANDIBLE
STERNUM
RIBS
HUMERUS
FEMUR

HEMATOPOIESIS PROCESS - ANSWER: STEM CELLS-->DIFFERENTIATION-->KEEPS
SOME AS STEM CELLS-->MYELOID/PROGENITOR CELLS-->RBC'S

DO INFANTS HAVE INCREASED OR DECREASED WBC/RBC COUNTS AT BIRTH? -
ANSWER: ELEVATED

WHAT IS ANOTHER NAME FOR BONE MARROW? - ANSWER: MYELOID TISSUE

WHAT HORMONE STIMULATES ERYTHROCYTE PRODUCTION? - ANSWER:
ERYTHROPOIETIN

WHAT IS ERYTHROPOIESIS? - ANSWER: DEVELOPMENT OF RBC'S

ERYTHROCYTES DERIVED FROM? - ANSWER: ERYTHROBLASTS

WHAT CONVERTS YELLOW BONE MARROW TO HEMATOPOIETIC RED MARROW? -
ANSWER: ERYTHROPOIETIN

WHERE IS ERYTHROPOIETIN PRODUCED? - ANSWER: PERTIBULAR CELLS OF KIDNEY

WHAT FEEDBACK LOOP IS USED IN ERYTHROPOIESIS? - ANSWER: NEGATIVE
FEEDBACK LOOP

,WHEN IS ERYTHROPOIETIN RELEASED? - ANSWER: IN RESPONSE TO LOW RENAL
OXYGENATION

HOW FAST CAN ERYTHROPOIETIN INCREASE RBC PRODUCTION? - ANSWER: 24
HOURS
INCREASED RBC NUMBER IN 5 DAYS

WHAT IS ERYTHROPOIETIN LIFE SPAN? - ANSWER: 4-12 HOURS

ERYTHROPOIETIN IS ALWAYS PRESENT WHERE? - ANSWER: IN THE PLASMA

WHAT TYPES OF PATIENTS ARE GIVEN ERYTHROPOIETIN? - ANSWER: DIALYSIS AND
CHEMO PATIENTS

THESE PT'S ARE ANEMIC, SO GIVEN EPO TO STIMULATE ERYTHROPOIESIS

GIVEN SEVERAL TIMES PER WEEK
GOAL TO INCREASE HEMATOCRIT TO 33%

WHAT IS THE LAST IMMATURE FORM OF THE ERYTHROBLAST? - ANSWER:
RETICULOCYTE

MEASURING A RETICULOCYTE COUNT IS A GOOD INDICATOR OF WHAT? - ANSWER:
ERYTHROPOIESIS (NEW RBC'S BEING MADE)

WHAT IS HEMOGLOBIN? - ANSWER: OXYGEN CARRYING PORTION OF THE RBC'S

NORMAL HEMOGLOBIN - ANSWER: 13-16GM/DL

WHAT MOLECULE IS ATTACHED TO HEME ON HEMOGLOBIN? - ANSWER: OXYGEN

EACH HEMOGLOBIN MOLECULE HAS HOW MANY GLOBIN CHAINS? - ANSWER: 2

EACH HEMOGLOBIN MOLECULE HAS HOW MANY COMPLEXES OF IRON AND HEME?
- ANSWER: 4

WHERE IS HEME SYNTHESIZED? - ANSWER: MITOCHONDRIA

HEME CARRIES HOW MANY OXYGEN MOLECULES? - ANSWER: 1

EVERY MOLECULE OF HEMOGLOBIN CARRIES HOW MANY OXYGEN? - ANSWER: 4

WHAT IS GLOBIN? - ANSWER: PROTEIN THAT CONTAINS HEME

MOST COMMON GLOBIN CHAIN? - ANSWER: HGB-A

2 ALPHA CHAINS

, 2 BETA CHAINS

WHAT DO RBC'S USE FOR ENERGY? - ANSWER: GLYCOLYSIS

DO RBC'S HAVE MITOCHONDRIA? - ANSWER: NO

THUS, NO ATP

TRANSFERRIN TURNS TO WHAT? - ANSWER: FERRITIN

G6PD DOES WHAT? - ANSWER: PROTECTS RBC'S AGAINST OXIDATIVE STRESS

WHAT IS ANEMIA? - ANSWER: REDUCTION IN THE TOTAL NUMBER OF
ERYTHROCYTES IN THE CIRCULATING BLOOD

ANISOCYTOSIS? - ANSWER: RBC'S ARE VARIOUS SIZES

POIKLOCYTOSIS? - ANSWER: RBC'S ARE VARIOUS SHAPES

IRON-DEFICIENCY ANEMIA PATHO - ANSWER: INADEQUATE DIETARY INTAKE
BLOOD LOSS
PARASITE INFECTIONS
MENORRHAGIA*
GI BLEED*

IRON-DEFICIENCY CLINICAL MANIFESTATIONS - ANSWER: COGNITIVE IMPAIRMENT
IN CHILDREN
NO SYMPTOMS MILD ANEMIA
DYSNPLEA
PICA* (PREGNANT LADIES)

LAB VALUES FOR IRON DEFICIENCY ANEMIA - ANSWER: LOW FERRITIN (MOST
SENSITIVE TEST FOR IDA)
LOW SERUM IRON
HIGH TIBC****

IF THERE IS NOT ENOUGH IRON TO BIND TO TRANSFERRIN, WILL THE TIBC BE HIGH
OR LOW? - ANSWER: HIGH TIBC

SIDEROBLASTIC ANEMIA PATHO - ANSWER: PROBLEM WITH HEME
DEFECT IN MITOCHONDRIAL HEME SYNTHESIS*
DYSFUNCTIONAL HEMOGLOBIN SYNTHESIS*

SIDEROBLASTIC ANEMIA CLINICAL MANIFESTATIONS - ANSWER: IRON OVERLOAD
ENLARGED SPLEEN AND LIVER

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