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Pathophysiology A Practical Approach Fifth Edition Lachel Story TESTBANK

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Pathophysiology A Practical Approach Fifth Edition Lachel Story TESTBANK

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Chapter: Chapter 01 - Quiz



Multiple Choice



1. A 22-year-old obese female patient comes into the clinic complaining of an earache and hearing loss in
the right ear. Assessment reveals temperature 101.2ºF (38.4 ºC), low-set ears, a wide neck, and droopy
eyelids. Patient reports a history of “kidney and heart problems” as well as “being born different.” Based
on these findings, what chromosomal disorder does this patient likely have?
A) Down syndrome
B) Turner’s syndrome
C) Klinefelter’s syndrome
D) Fragile X syndrome



2. Metaplasia is:
A) the disorganization of cells into various sizes, shapes, and arrangements.
B) the replacement of one differentiated cell type with another.
C) the transformation of a cell type to malignancy.
D) an irreversible cellular adaptation.



3. What information should parents be given about the consequences of phenylketonuria (PKU)?
A) Severe intellectual disability is inevitable.
B) PKU is commonly associated with other congenital anomalies.
C) High dietary tyramine may help induce enzyme production.
D) Failure to treat properly results in progressive intellectual disability.



4. Injury that occurs when blood flow is diminished to tissue is called _____ injury.
A) hypoxic
B) ischemic
C) hyperemic
D) neoplastic

,5. Characteristics of X-linked recessive disorders include which of the following?
A) The son of a carrier mother has a 25% chance of being affected.
B) Affected fathers transmit the gene to all of their sons.
C) All daughters of affected fathers are carriers.
D) Boys and girls are equally affected.



6. The cancer growth continuum is divided into which of the following stages?
A) Stage 1, stage 2, stage 3
B) Initiation, progression, promotion
C) Preliminary, evolutionary, metastasis
D) Initiation, promotion, progression



7. The activities of the cell are directed by which cell structure?
A) Cytoplasm
B) Organelles
C) Cell membranes
D) Nucleus



8. DNA is composed of base chemicals called:
A) adenine, thymine, guanine, and cytosine.
B) nucleotide, deoxyribose, and base.
C) chromosomes and proteins.
D) None of these are correct.



9. Dysplasia of epithelial cells sometimes results from which of the following?
A) Excessive sodium intake
B) Chronic irritation or inflammation
C) Increased enzyme synthesis
D) Apoptosis



10. The function of lysosomes is to:
A) break down particles or worn-out cellular components.
B) convert food materials into energy.
C) produce digestive enzymes and antibody proteins.
D) aid in cell division.



11. A __________ gene expresses itself in either the heterozygous or the homozygous state.
A) dominant
B) recessive
C) sex-linked
D) hemizygous

, 12. __________ syndrome occurs in men when there is an extra X chromosome.
A) Triple X
B) Turner’s
C) Klinefelter’s
D) XYY



13. A metastatic tumor is one that:
A) has spread to a location away from its site of origin.
B) shows slow expansion and well-differentiated cells.
C) cannot be classified easily.
D) invades deeply into the tissue where it arose.



14. Children with PKU must avoid phenylalanine in the diet. Phenylalanine is most likely to be a
component of:
A) fat.
B) sugar.
C) protein.
D) carbohydrate.



15. A routine ultrasound of a 38-year-old woman of 26 weeks’ gestation reveals a fetus with a small
square head, upward slant of the eyes, and low set ears. The nurse recognizes that these findings are
consistent with which of the following?
A) Fragile X syndrome
B) Monosomy X (Turner’s syndrome)
C) Trisomy 21 (Down syndrome)
D) Trisomy X (Klinefelter’s syndrome)



16. While discussing treatment options with a parent of a newly diagnosed monosomy X (Turner’s
syndrome) child, the nurse should include which of the following?
A) “There is no treatment or cure.”
B) “Symptoms of the condition are treated with estrogen.”
C) “Symptoms of the condition are treated with testosterone.”
D) “Institutionalization is the preferred method of managing care.”



17. Tay-Sachs is caused by which of the following?
A) A deficiency or absence of hexosaminidase A
B) A defect on chromosome 17 or 22
C) A mutation on chromosome 15
D) An error in converting phenylalanine to tyrosine

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