Nurs 6521N - Advanced Pharmacology
midterm exam with complete solutions
2024/2025
What are the two components of prescriptive authority
The right to prescribe independently
And the right to prescribe without limitation
The regulation for prescriptive Authority comes from
The State Board of Nursing
The State Board of Medicine
State Board of Pharmacy
What is the most important function to evaluate when prescribing a medication
Hepatic and renal function
What must you pay attention to when performing a refill
1. Is this a newer medication for a patient
2. changing the dose of frequency
3. am I adding new medicines to their regimen
4. is this patient having undesired effects
5. How long has it been since I've seen the patient
6. Is this a Schedule II medication
*If the answer to any of these questions is yes consider a shorter time period for
a refill (one to three months)
What should be included in the teaching for drug monitoring
What test is needed
When is test required
Where will testing take place
Why is testing necessary
How does the patient prepare for testing
, What periodic Laboratory Testing is needed with Ace and ARB
Potassium/ creatinine
These drugs can cause hyperkalemia
Renal perfusion is dependent on Angiotensin in some patients increased
creatinine may require a change in medication
What LaboratoryTesting is required with amiodarone
Liver function, thyroid function, pulmonary function and chest x-rays
Hepatoxicity is an adverse effect
Either hypo or hyperthyroidism may occur
Pulmonary toxicity is not uncommon, affects maybe permanent
What Laboratory Testing is required with anticonvulsants
Serum drug levels-some have a very narrow therapeutic index
What Laboratory Testing is required with lithium
CBC, lithium level, thyroid function, renal function, serum electrolytes
This drug has a narrow therapeutic margin,
lithium can cause leukocyte elevation
Both hypo and hyperthyroidism may occur
Renal damage is a serious adverse effect
Nephrogenic diabetes insipidus May occur, and hyponatremia can create
complications
What are the four basic pharmacokinetic processes
absorption, distribution, metabolism, excretion
What is the combination of metabolism and excretion called
Elimination
What determines the concentration of a drug at its site of action
The four pharmacokinetic processes acting in concert
What are the three ways for drugs to cross the cell membrane
Passage through channels or pores
Passage with the aid of a transport system
Direct penetration of the membrane
Of all three direct penetration of the membrane is most common
What is an example of a drug that can pass through a Channel or poor
Sodium or potassium
What are common drug transporters
Pgp- P - glycoprotein
What is the general rule in chemistry
dissolve like Membranes are composed primarily of lipids-therefore to directly
penetrate membranes a drug must be lipid soluble or lipophilic
midterm exam with complete solutions
2024/2025
What are the two components of prescriptive authority
The right to prescribe independently
And the right to prescribe without limitation
The regulation for prescriptive Authority comes from
The State Board of Nursing
The State Board of Medicine
State Board of Pharmacy
What is the most important function to evaluate when prescribing a medication
Hepatic and renal function
What must you pay attention to when performing a refill
1. Is this a newer medication for a patient
2. changing the dose of frequency
3. am I adding new medicines to their regimen
4. is this patient having undesired effects
5. How long has it been since I've seen the patient
6. Is this a Schedule II medication
*If the answer to any of these questions is yes consider a shorter time period for
a refill (one to three months)
What should be included in the teaching for drug monitoring
What test is needed
When is test required
Where will testing take place
Why is testing necessary
How does the patient prepare for testing
, What periodic Laboratory Testing is needed with Ace and ARB
Potassium/ creatinine
These drugs can cause hyperkalemia
Renal perfusion is dependent on Angiotensin in some patients increased
creatinine may require a change in medication
What LaboratoryTesting is required with amiodarone
Liver function, thyroid function, pulmonary function and chest x-rays
Hepatoxicity is an adverse effect
Either hypo or hyperthyroidism may occur
Pulmonary toxicity is not uncommon, affects maybe permanent
What Laboratory Testing is required with anticonvulsants
Serum drug levels-some have a very narrow therapeutic index
What Laboratory Testing is required with lithium
CBC, lithium level, thyroid function, renal function, serum electrolytes
This drug has a narrow therapeutic margin,
lithium can cause leukocyte elevation
Both hypo and hyperthyroidism may occur
Renal damage is a serious adverse effect
Nephrogenic diabetes insipidus May occur, and hyponatremia can create
complications
What are the four basic pharmacokinetic processes
absorption, distribution, metabolism, excretion
What is the combination of metabolism and excretion called
Elimination
What determines the concentration of a drug at its site of action
The four pharmacokinetic processes acting in concert
What are the three ways for drugs to cross the cell membrane
Passage through channels or pores
Passage with the aid of a transport system
Direct penetration of the membrane
Of all three direct penetration of the membrane is most common
What is an example of a drug that can pass through a Channel or poor
Sodium or potassium
What are common drug transporters
Pgp- P - glycoprotein
What is the general rule in chemistry
dissolve like Membranes are composed primarily of lipids-therefore to directly
penetrate membranes a drug must be lipid soluble or lipophilic
