NURS 5315 Actual Exam | Questions with
Answers Verified 100% Correct
What does the thymus provide in regards to immunity? - ✔✔-thymus shrinks as we grow
-provides T-cell differentiation, maturation & selection
What does the spleen provide in regards to immunity? - ✔✔-lymphoid organ & contains
blood filled sinuses that filter antigens & cells from the blood
What are the peyer patches? - ✔✔-Red pulp: location of RBC storage & turnover
-White pulp: site where immune interaction occurs
What triggers an immune response? - ✔✔-antigens presenting cells present antigens to
lymphocytes in the spleen
Which persons are at increased for high risk of infection, esp. infections caused by streptococcal
bacteria? - ✔✔- had their spleen removed
-have a nonfunctional spleen, ex) sickle cell disease
Which individuals require pneumococcal vaccine? - ✔✔-sickle cell
-nonfuctional spleen or spleen removed
What are the sites where antigens interact with immune cells? - ✔✔-lymph nodes
-tonsils
-peyer patches (red pulp,white pulp)
,Which T-Cells are governed by the Cell-Mediated Immunity/Response (CD)? - ✔✔-CD4 cells
(T-helper or T4 cells)
-CD8 cells (Killer T's or T8 cells)
-Memory T-Cells
-T-Regulatory Cells
What does "CD" refer to in the Cell Mediated Immune Response? - ✔✔cluster of
differentiation
CD4 cells (T-helper or T4 cells) are responsible for _______ in the immune response? - ✔✔-
activate macrophages,B-cells, cytoxic T-cells & other CD4 cells
-release lymphokines:begin inflammatory process & mediate hypersensitivity reactions
-ex)TB skin test
Example of an CD4 inflammatory response & mediate delayed hypersensitivity reaction is
________? - ✔✔TB skin test
Cells responsible for releasing lymphokines are _____? - ✔✔-TH1
-TH2
both are preformed by a subgroup of CD4 cells
Define CD8 (Killer T's , T8 cells) cells: - ✔✔-kill virus infected cells, tumor cells & allograft cells
(transplant tissue
-release cytoxic chemicals that destroy cell membrane or induce apoptosis
What role do Memory T-cells play in the cell mediated immune response? - ✔✔-allow host
to remember antigens
-respond quicker & vigorously after initial response
-live for many years
,-can reproduce themselves
What role do T-regulatory cells play in the cell medicated immune response? - ✔✔-slow or
stop immune response once invader is defeated
Humoral Immune Response is governed by_______? - ✔✔-B-cells
-B-cells mature into plasma cells that then produce antibodies
Name the 5 classes of antibodies(glycoproteins) in the Humoral Immune Response - ✔✔-IgG
-IgE
-IgM
-IgA
-IgD
IgG antibody is role is to ___________? - ✔✔-bind with viruses, bacteria & toxins
-most prominent immune globulin
-activates complement & binds to macrophages
What is the primary antibody in the secondary immune response? - ✔✔-IgG
What happens to the IgG antibody level in response to a subsequent exposure to an antigen? -
✔✔-IgG level rises
Which is the only immune globulin that crosses the placentia? - ✔✔-IgG
What is IgE's role in the Humoral Immune Response? - ✔✔-involved in parasitic infections &
hypersensitivity reactions
-binds to mast cells, eosinophils & basophils
, Which antibody is responsible for hypersensitivity reactions & parasitic infections? - ✔✔IgE
What is IgM's role in the Humoral Immune Response? - ✔✔-main immune globulin produced
early in primary immune response
What antibody is produced early in a primary response? - ✔✔IgM
If a high IgM level is seen on laboratory, what does this indicate? - ✔✔-recent infection
IgA's role in the Humoral Immune Response is _______? - ✔✔-main immune globulin in
secretions & mucous membranes
-prevents attachment of microorganisms to the mucous membrane
What is the IgD role in the Humoral Immune Response? - ✔✔-signals B-cell activation
-found on the surface of B-lymphocytes
What activates the complement cascade? - ✔✔-antibodies coat the bacteria to enhance
phagocytosis & form antigen antibody complexes
The overall function of antibodies include_____? - ✔✔-neutralization of bacterial toxins, this
activates the complement cascade
Upon exposure to an antigen , the immune system will mount a response within
________________________ days? - ✔✔5-7 days
Primary immune response is characterized by a ________of ______ antibodies and later in the
course of an infection a ______ of _____________ antibodies. - ✔✔1)rise
Answers Verified 100% Correct
What does the thymus provide in regards to immunity? - ✔✔-thymus shrinks as we grow
-provides T-cell differentiation, maturation & selection
What does the spleen provide in regards to immunity? - ✔✔-lymphoid organ & contains
blood filled sinuses that filter antigens & cells from the blood
What are the peyer patches? - ✔✔-Red pulp: location of RBC storage & turnover
-White pulp: site where immune interaction occurs
What triggers an immune response? - ✔✔-antigens presenting cells present antigens to
lymphocytes in the spleen
Which persons are at increased for high risk of infection, esp. infections caused by streptococcal
bacteria? - ✔✔- had their spleen removed
-have a nonfunctional spleen, ex) sickle cell disease
Which individuals require pneumococcal vaccine? - ✔✔-sickle cell
-nonfuctional spleen or spleen removed
What are the sites where antigens interact with immune cells? - ✔✔-lymph nodes
-tonsils
-peyer patches (red pulp,white pulp)
,Which T-Cells are governed by the Cell-Mediated Immunity/Response (CD)? - ✔✔-CD4 cells
(T-helper or T4 cells)
-CD8 cells (Killer T's or T8 cells)
-Memory T-Cells
-T-Regulatory Cells
What does "CD" refer to in the Cell Mediated Immune Response? - ✔✔cluster of
differentiation
CD4 cells (T-helper or T4 cells) are responsible for _______ in the immune response? - ✔✔-
activate macrophages,B-cells, cytoxic T-cells & other CD4 cells
-release lymphokines:begin inflammatory process & mediate hypersensitivity reactions
-ex)TB skin test
Example of an CD4 inflammatory response & mediate delayed hypersensitivity reaction is
________? - ✔✔TB skin test
Cells responsible for releasing lymphokines are _____? - ✔✔-TH1
-TH2
both are preformed by a subgroup of CD4 cells
Define CD8 (Killer T's , T8 cells) cells: - ✔✔-kill virus infected cells, tumor cells & allograft cells
(transplant tissue
-release cytoxic chemicals that destroy cell membrane or induce apoptosis
What role do Memory T-cells play in the cell mediated immune response? - ✔✔-allow host
to remember antigens
-respond quicker & vigorously after initial response
-live for many years
,-can reproduce themselves
What role do T-regulatory cells play in the cell medicated immune response? - ✔✔-slow or
stop immune response once invader is defeated
Humoral Immune Response is governed by_______? - ✔✔-B-cells
-B-cells mature into plasma cells that then produce antibodies
Name the 5 classes of antibodies(glycoproteins) in the Humoral Immune Response - ✔✔-IgG
-IgE
-IgM
-IgA
-IgD
IgG antibody is role is to ___________? - ✔✔-bind with viruses, bacteria & toxins
-most prominent immune globulin
-activates complement & binds to macrophages
What is the primary antibody in the secondary immune response? - ✔✔-IgG
What happens to the IgG antibody level in response to a subsequent exposure to an antigen? -
✔✔-IgG level rises
Which is the only immune globulin that crosses the placentia? - ✔✔-IgG
What is IgE's role in the Humoral Immune Response? - ✔✔-involved in parasitic infections &
hypersensitivity reactions
-binds to mast cells, eosinophils & basophils
, Which antibody is responsible for hypersensitivity reactions & parasitic infections? - ✔✔IgE
What is IgM's role in the Humoral Immune Response? - ✔✔-main immune globulin produced
early in primary immune response
What antibody is produced early in a primary response? - ✔✔IgM
If a high IgM level is seen on laboratory, what does this indicate? - ✔✔-recent infection
IgA's role in the Humoral Immune Response is _______? - ✔✔-main immune globulin in
secretions & mucous membranes
-prevents attachment of microorganisms to the mucous membrane
What is the IgD role in the Humoral Immune Response? - ✔✔-signals B-cell activation
-found on the surface of B-lymphocytes
What activates the complement cascade? - ✔✔-antibodies coat the bacteria to enhance
phagocytosis & form antigen antibody complexes
The overall function of antibodies include_____? - ✔✔-neutralization of bacterial toxins, this
activates the complement cascade
Upon exposure to an antigen , the immune system will mount a response within
________________________ days? - ✔✔5-7 days
Primary immune response is characterized by a ________of ______ antibodies and later in the
course of an infection a ______ of _____________ antibodies. - ✔✔1)rise
