USE IN THE FETUS AND NEONATE
QUESTIONS WITH VERIFIED ANSWERS
{ GRADED A+}
patients, physicians, and pharmacists all cite _____ as a top priority
when making decisions about medication use - ✔✔safety of the mother
and fetus
T/F? safety data for the vast majority of medications is limited -
✔✔TRUE
T/F? most of the drugs administered to the mother reach the fetus -
✔✔TRUE
, The extent of fetal exposure depends on ___ and ___? - ✔✔maternal
drug disposition
placental drug transfer
the steady-state concentration of the drug in maternal circulation,
which ultimately determines the amount of the drug available for
distribution to the fetal compartment - ✔✔maternal drug disposition
the maternal drug disposition is impacted in varying degrees by
maternal _____, all of which are altered during pregnancy -
✔✔maternal absorption, distribution, metabolism, and excretion of
drug
drug absorption in mom is affected by ____ and ____? - ✔✔gastric
emptying time and intestinal motility
is gastric emptying time increased or decreased during pregnancy?
which causes what? - ✔✔increased
reduced rate of absorption