CSO EXAM TEST BANK LATEST REAL EXAM 250
QUESTIONS AND CORRET ANSWERS WITH RATIONALES
(DETAILED ANSWERS) |ALREADY GRADED A+
Hormone Therapy - ANSWER: Used to treat hormone sensitive cancers. Stops or
reduces the body's ability to produce hormones. Also, substitutes chemically similar
agents for the active hormones that cannot be used by the tumor. Ex: SERMS, AIs,
Progesterones, Antiandrogens, LHRH.
Immunomodulatory Drugs - ANSWER: Inhibit anti-inflammatory cytokines and exert
anti-angiogenic properties. Ex: Revlimid, Thaudomide
Adjuvant Therapy - ANSWER: The use of additional cancer treatment given after the
primary therapy. Ex: chemo after lobectomy
Definitive Therapy - ANSWER: Prescribed treatment modality with or without
additional treatment
Neoadjuvant Therapy - ANSWER: The use of one or more treatment modalities given
before the primary treatment.
Biotherapy - ANSWER: Treatment to boost or restore the ability of the immune
system to fight cancer by inducing, enhancing, or suppressing the immune system
response. Also called immunotherapy.
Monoclonal Antibodies - ANSWER: Therapies that signal external cellular pathway
targets which activate pathways inside. Disrupts cell function and causes cell
apoptosis.
Protein Targeted Therapies - ANSWER: Therapies the signal internal cellular pathway
that targets proteins. Ex: TKIs, MTOR inhibitor, Proteasome Inhibitor.
Angiogenesis Inhibitor - ANSWER: Hinder the formation of new blood vessels in
primary tumors thus preventing their growth, invasion, and spread.
Cytokines - ANSWER: Stimulate immune response, encourage cell growth, promote
cell activation, destroy cancer cells. Ex: Interleukin or Interferon.
Low Risk of Emesis Chemo - ANSWER: Bleomycin
Busulfan
Fludarabine
Vinblastine
Vincristine
Vinorelbine
Bevacizumab
,Anti-Emetic Drugs - ANSWER: 1. Serotonin 5-HT3 (zofran, dolasetron, granisetron,
palonsetron)
2. Dexamethasone (corticosteroid)
3. Aprepitant (NK1 receptor antagonist) Rezonic (casopitant) or Emend (aprepitant)
Chemo that damages GI Tract - ANSWER: Methotrexate
Melphalan
Irinotecan
Fluorouracil
High Risk of Emesis Chemo - ANSWER: Cisplatin
Mechlorthamine
Cyclophosphamide
Carmustine
Dacarbazine
Moderate Risk of Emesis Chemo - ANSWER: Oxaliplatin
Cytarabine
Carboplatin
Ifosfamide
Cyclophosphamide
Doxorubicin
Daurorubicin
Epirubicin
Idarubicin
Irinotecan
Beta Carotene - ANSWER: Antioxidant
Conventional Food: Carrots, oranges, red/yellow foods
Functional Food: Beta carotene rich juice
B-glucans - ANSWER: Natural polysaccharide and soluble fiber that may boost the
immune system.
Conventional Food: barley, oats, fruits, vegetables, seaweed.
Functional Food: B-glucan enriched breakfast cereals, breads, snack bars, bran
products, and milk beverages.
Genistein - ANSWER: May block estrogen receptors; early exposure may decrease
breast cancer risk.
Conventional Food: soy good, edamame, tofu, soy milk
Functional Food: variety of snack foods including snack bars.
Inulin - ANSWER: Exhibits prebiotic activity which can enhance intestinal health.
Conventional Food: onions, shallots, jerusalem shallots.
Functional Food: used as fat replacement; added to beverages and jellies.
, Lignans - ANSWER: Phytoestrogen; associated with decreased risk of breast cancer.
Conventional Food: Flaxseed, sesame seed, chickpea, oats, barley
Functional Food: flaxseed added to snack bars and muffins
Lutein - ANSWER: Xanthophyll; antimutagenic and anticarcinogenic properties.
Conventional Food: dark green leafy vegs, spinach, kale, broccoli, squash, green
peas, lettuce, onions, corn, pumpkin, egg yolk
Functional Food: added to ready to eat cereal
Lycopene - ANSWER: Antioxidant; blocks activity of free radicals.
Conventional Food: tomatoes/products, red, yellow, and orange fruits and
vegetables
Functional Food: added to ready to eat cereal
Omega 3 - ANSWER: Anti-inflammatory effect.
Conventional Food: Fatty fish (mackerel, trout, herring, tuna, salmon, sardines)
Functional Food: eggs fortified with omega 3 fats
Soluble Fiber - ANSWER: Promote intestinal health.
Conventional Food: oats, lentils, apples, oranges, bananas, pears, strawberries, nuts,
flaxseed, beans, dried peas, blueberries.
Functional Food: banana flakes, ready to eat cereal
Oleic Acid - ANSWER: Omega 9 FA; found in olive oil and avocado. May be synergistic
with Perception. Not sold as supplement.
Omega 3 - ANSWER: May reduce toxicity of Irinotecan and Paclitaxel.
May increase benefit of doxorubicin, cisplatin, and vincristine.
Food sources and supplements.
Melatonin - ANSWER: May increase response of Tamoxifen.
Theanine - ANSWER: Antioxidant; Increases benefits/decreases toxicity of
doxorubicin and idarubicin.
Found in Tea.
Coenzyme-Q10 - ANSWER: Antioxidant made in body.
May reduce renal and cardio toxicity of doxorubicin.
May interfere with chemo or warfarin.
May cause nausea, vomiting, or diarrhea.
Aloe Vera - ANSWER: Laxative Effect
Glutamine - ANSWER: Essential for GI health and wound healing.
May lessen: mucositis, stomatitis, esophagitis, and diarrhea.
May decrease efficacy of Lactulose and seizure meds.
QUESTIONS AND CORRET ANSWERS WITH RATIONALES
(DETAILED ANSWERS) |ALREADY GRADED A+
Hormone Therapy - ANSWER: Used to treat hormone sensitive cancers. Stops or
reduces the body's ability to produce hormones. Also, substitutes chemically similar
agents for the active hormones that cannot be used by the tumor. Ex: SERMS, AIs,
Progesterones, Antiandrogens, LHRH.
Immunomodulatory Drugs - ANSWER: Inhibit anti-inflammatory cytokines and exert
anti-angiogenic properties. Ex: Revlimid, Thaudomide
Adjuvant Therapy - ANSWER: The use of additional cancer treatment given after the
primary therapy. Ex: chemo after lobectomy
Definitive Therapy - ANSWER: Prescribed treatment modality with or without
additional treatment
Neoadjuvant Therapy - ANSWER: The use of one or more treatment modalities given
before the primary treatment.
Biotherapy - ANSWER: Treatment to boost or restore the ability of the immune
system to fight cancer by inducing, enhancing, or suppressing the immune system
response. Also called immunotherapy.
Monoclonal Antibodies - ANSWER: Therapies that signal external cellular pathway
targets which activate pathways inside. Disrupts cell function and causes cell
apoptosis.
Protein Targeted Therapies - ANSWER: Therapies the signal internal cellular pathway
that targets proteins. Ex: TKIs, MTOR inhibitor, Proteasome Inhibitor.
Angiogenesis Inhibitor - ANSWER: Hinder the formation of new blood vessels in
primary tumors thus preventing their growth, invasion, and spread.
Cytokines - ANSWER: Stimulate immune response, encourage cell growth, promote
cell activation, destroy cancer cells. Ex: Interleukin or Interferon.
Low Risk of Emesis Chemo - ANSWER: Bleomycin
Busulfan
Fludarabine
Vinblastine
Vincristine
Vinorelbine
Bevacizumab
,Anti-Emetic Drugs - ANSWER: 1. Serotonin 5-HT3 (zofran, dolasetron, granisetron,
palonsetron)
2. Dexamethasone (corticosteroid)
3. Aprepitant (NK1 receptor antagonist) Rezonic (casopitant) or Emend (aprepitant)
Chemo that damages GI Tract - ANSWER: Methotrexate
Melphalan
Irinotecan
Fluorouracil
High Risk of Emesis Chemo - ANSWER: Cisplatin
Mechlorthamine
Cyclophosphamide
Carmustine
Dacarbazine
Moderate Risk of Emesis Chemo - ANSWER: Oxaliplatin
Cytarabine
Carboplatin
Ifosfamide
Cyclophosphamide
Doxorubicin
Daurorubicin
Epirubicin
Idarubicin
Irinotecan
Beta Carotene - ANSWER: Antioxidant
Conventional Food: Carrots, oranges, red/yellow foods
Functional Food: Beta carotene rich juice
B-glucans - ANSWER: Natural polysaccharide and soluble fiber that may boost the
immune system.
Conventional Food: barley, oats, fruits, vegetables, seaweed.
Functional Food: B-glucan enriched breakfast cereals, breads, snack bars, bran
products, and milk beverages.
Genistein - ANSWER: May block estrogen receptors; early exposure may decrease
breast cancer risk.
Conventional Food: soy good, edamame, tofu, soy milk
Functional Food: variety of snack foods including snack bars.
Inulin - ANSWER: Exhibits prebiotic activity which can enhance intestinal health.
Conventional Food: onions, shallots, jerusalem shallots.
Functional Food: used as fat replacement; added to beverages and jellies.
, Lignans - ANSWER: Phytoestrogen; associated with decreased risk of breast cancer.
Conventional Food: Flaxseed, sesame seed, chickpea, oats, barley
Functional Food: flaxseed added to snack bars and muffins
Lutein - ANSWER: Xanthophyll; antimutagenic and anticarcinogenic properties.
Conventional Food: dark green leafy vegs, spinach, kale, broccoli, squash, green
peas, lettuce, onions, corn, pumpkin, egg yolk
Functional Food: added to ready to eat cereal
Lycopene - ANSWER: Antioxidant; blocks activity of free radicals.
Conventional Food: tomatoes/products, red, yellow, and orange fruits and
vegetables
Functional Food: added to ready to eat cereal
Omega 3 - ANSWER: Anti-inflammatory effect.
Conventional Food: Fatty fish (mackerel, trout, herring, tuna, salmon, sardines)
Functional Food: eggs fortified with omega 3 fats
Soluble Fiber - ANSWER: Promote intestinal health.
Conventional Food: oats, lentils, apples, oranges, bananas, pears, strawberries, nuts,
flaxseed, beans, dried peas, blueberries.
Functional Food: banana flakes, ready to eat cereal
Oleic Acid - ANSWER: Omega 9 FA; found in olive oil and avocado. May be synergistic
with Perception. Not sold as supplement.
Omega 3 - ANSWER: May reduce toxicity of Irinotecan and Paclitaxel.
May increase benefit of doxorubicin, cisplatin, and vincristine.
Food sources and supplements.
Melatonin - ANSWER: May increase response of Tamoxifen.
Theanine - ANSWER: Antioxidant; Increases benefits/decreases toxicity of
doxorubicin and idarubicin.
Found in Tea.
Coenzyme-Q10 - ANSWER: Antioxidant made in body.
May reduce renal and cardio toxicity of doxorubicin.
May interfere with chemo or warfarin.
May cause nausea, vomiting, or diarrhea.
Aloe Vera - ANSWER: Laxative Effect
Glutamine - ANSWER: Essential for GI health and wound healing.
May lessen: mucositis, stomatitis, esophagitis, and diarrhea.
May decrease efficacy of Lactulose and seizure meds.
