Drug Discovery Final Exam UPDATED
ACTUAL Exam Questions and CORRECT
Answers
In the scientific method, once a hypothesis has been made, the next step is: - CORRECT
ANSWER✔✔- To make a prediction based on the hypothesis.
A theory is: - CORRECT ANSWER✔✔- based on many observations and experiments.
The scientific method: - CORRECT ANSWER✔✔- is a continuous cycle.
Laws of nature have been tested extensively and seem to apply everywhere in the universe. T
or F? - CORRECT ANSWER✔✔- True.
The first clinical trial addressed: - CORRECT ANSWER✔✔- Scurvy.
Scurvy occurs because of deficiency in - CORRECT ANSWER✔✔- Vitamin C.
Pellagra occurs because of deficiency in - CORRECT ANSWER✔✔- Vitamin B3
Clinical trial of Patulin - CORRECT ANSWER✔✔- First introduced placebo to the world.
The cost of a new drug (from research through FDA approval) is - CORRECT
ANSWER✔✔- More than $1 billion
A pharmaceutical company will be more likely developing a new drug against progeria
(affecting less than 100 people world-wide) than rheumatoid arthritis (affects more than 1.5
million people in the USA alone). T or F? - CORRECT ANSWER✔✔- False
Investigational new drug application (IND) is filed: - CORRECT ANSWER✔✔- Before
Phase I clinical trial.
, New drug application (NDA) is filed - CORRECT ANSWER✔✔- During Phase III clinical
trial.
Phase IV clinical trials - CORRECT ANSWER✔✔- Are conducted after a drug has been
approved for consumer sales, and Compare the new drug with similar drugs already on the
market.
A new drug is approved for sales after - CORRECT ANSWER✔✔- Phase III clinical trial.
Generic drugs always have the same efficiency as the brand-name drugs because their
chemical structures should be identical. T or F? - CORRECT ANSWER✔✔- False.
Half-life of a drug in the body most critically depends on the rate of - CORRECT
ANSWER✔✔- Metabolism the liver.
With respect to protein structure, alpha-helix is an example of: - CORRECT ANSWER✔✔-
Secondary Structure
What is true about the genetic code? - CORRECT ANSWER✔✔- In DNA molecules three
sequential nucleotides encode one amino acid, All life on Earth is based on one genetic code,
Genetic code is redundant.
Genetic engineering means that - CORRECT ANSWER✔✔- Organisms with specified
changes in the genome are produced.
As its main function, the liver is - CORRECT ANSWER✔✔- A gatekeeper, which detoxifies
chemicals and metabolizes drugs coming from the digestive tract.
Most of the orally administered drugs are absorbed in the - CORRECT ANSWER✔✔- Small
intestine.
Most of the drug targets are - CORRECT ANSWER✔✔- Proteins.
ACTUAL Exam Questions and CORRECT
Answers
In the scientific method, once a hypothesis has been made, the next step is: - CORRECT
ANSWER✔✔- To make a prediction based on the hypothesis.
A theory is: - CORRECT ANSWER✔✔- based on many observations and experiments.
The scientific method: - CORRECT ANSWER✔✔- is a continuous cycle.
Laws of nature have been tested extensively and seem to apply everywhere in the universe. T
or F? - CORRECT ANSWER✔✔- True.
The first clinical trial addressed: - CORRECT ANSWER✔✔- Scurvy.
Scurvy occurs because of deficiency in - CORRECT ANSWER✔✔- Vitamin C.
Pellagra occurs because of deficiency in - CORRECT ANSWER✔✔- Vitamin B3
Clinical trial of Patulin - CORRECT ANSWER✔✔- First introduced placebo to the world.
The cost of a new drug (from research through FDA approval) is - CORRECT
ANSWER✔✔- More than $1 billion
A pharmaceutical company will be more likely developing a new drug against progeria
(affecting less than 100 people world-wide) than rheumatoid arthritis (affects more than 1.5
million people in the USA alone). T or F? - CORRECT ANSWER✔✔- False
Investigational new drug application (IND) is filed: - CORRECT ANSWER✔✔- Before
Phase I clinical trial.
, New drug application (NDA) is filed - CORRECT ANSWER✔✔- During Phase III clinical
trial.
Phase IV clinical trials - CORRECT ANSWER✔✔- Are conducted after a drug has been
approved for consumer sales, and Compare the new drug with similar drugs already on the
market.
A new drug is approved for sales after - CORRECT ANSWER✔✔- Phase III clinical trial.
Generic drugs always have the same efficiency as the brand-name drugs because their
chemical structures should be identical. T or F? - CORRECT ANSWER✔✔- False.
Half-life of a drug in the body most critically depends on the rate of - CORRECT
ANSWER✔✔- Metabolism the liver.
With respect to protein structure, alpha-helix is an example of: - CORRECT ANSWER✔✔-
Secondary Structure
What is true about the genetic code? - CORRECT ANSWER✔✔- In DNA molecules three
sequential nucleotides encode one amino acid, All life on Earth is based on one genetic code,
Genetic code is redundant.
Genetic engineering means that - CORRECT ANSWER✔✔- Organisms with specified
changes in the genome are produced.
As its main function, the liver is - CORRECT ANSWER✔✔- A gatekeeper, which detoxifies
chemicals and metabolizes drugs coming from the digestive tract.
Most of the orally administered drugs are absorbed in the - CORRECT ANSWER✔✔- Small
intestine.
Most of the drug targets are - CORRECT ANSWER✔✔- Proteins.
