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Drug Discovery Final Exam ACTUAL Exam Questions and CORRECT Answers

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Drug Discovery Final Exam ACTUAL Exam Questions and CORRECT Answers Curcumin - CORRECT ANSWER- This structure shown represents: Nicotine - CORRECT ANSWER- ___________ was first isolated from dried tobacco leaves. Ribosomes - CORRECT ANSWER- Are the site of the protein synthesis in all living cells. $1 Billion - CORRECT ANSWER- To be considered a "blockbuster" a new drug should annually eclipse

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Drug Discovery Final Exam ACTUAL
Exam Questions and CORRECT Answers
Curcumin - CORRECT ANSWER✔✔- This structure shown represents:



Nicotine - CORRECT ANSWER✔✔- ___________ was first isolated from dried tobacco
leaves.


Ribosomes - CORRECT ANSWER✔✔- Are the site of the protein synthesis in all living
cells.


$1 Billion - CORRECT ANSWER✔✔- To be considered a "blockbuster" a new drug should
annually eclipse:


What is NOT true of proteins? - CORRECT ANSWER✔✔- They are vitamins.



Genes - CORRECT ANSWER✔✔- ______________ control your hair color, eye color and
disease state.


False - CORRECT ANSWER✔✔- Dr. Joseph Goldberger's thorough investigation of the
pellagra epidemic allowed him to discover that the reason for the disease was vitamin B3
deficiency.


Stomach - CORRECT ANSWER✔✔- Aspirin readily passes through the ___ to be absorbed
directly into the bloodstream unlike most drugs.


A systematic way of evaluating evidence. - CORRECT ANSWER✔✔- The scientific method,
which is very useful in many fields besides science, is simply:


All of the above are true.
(They are proteins, some facilitate bonding between molecules while others facilitate the
breakdown of molecules, and their monomer units are nucleotides. - CORRECT
ANSWER✔✔- What is not true of enzymes?

,Proteins - CORRECT ANSWER✔✔- Most of drug targets are:



Ma Huang - CORRECT ANSWER✔✔- Extract of ____________ was used to treat coughs in
ancient China.


It is destroyed by proteolytic enzymes in the GI tract. - CORRECT ANSWER✔✔- Insulin
cannot be taken orally because:


1982 - CORRECT ANSWER✔✔- The first genetically engineered drug was approved in:



False - CORRECT ANSWER✔✔- RNA most commonly forms a double helix.



ANDA - CORRECT ANSWER✔✔- The generic manufacturers must file with the FDA the
following type of application:


Root bark of the apple tree. - CORRECT ANSWER✔✔- The prototype of GLT2 inhibitor
drugs phlorizin was first isolated from:


The saliva of the Gila monster. - CORRECT ANSWER✔✔- Byetta is a synthetic version of
the peptide exendin-4, which is isolated from:


Metabolism in the liver. - CORRECT ANSWER✔✔- Half-life of a drug in. the body most
critically depends on the rate of:


Before Phase I clinical trial. - CORRECT ANSWER✔✔- Investigational new drug
application (IND) is filed:


Pancreas - CORRECT ANSWER✔✔- The _________ fails to function normally and produce
insulin in diabetics.

, A prediction. - CORRECT ANSWER✔✔- In science, every hypothesis must be tested by
using it to make:


Small intestine. - CORRECT ANSWER✔✔- Once a drug is swallowed, it passes through the
esophagus into the stomach and then - into the _______:


Discovered insulin and showed its potency for treatment of diabetic patients. - CORRECT
ANSWER✔✔- Dr. Charles Banting & Dr. H.J.R. Macleod were awarded the Nobel Prize
because they:


Pseudoephedrine - CORRECT ANSWER✔✔- Methamphetamine is illegally produced from:



What structure represents a ketone? - CORRECT ANSWER✔✔-



To assess safety of the new drug. - CORRECT ANSWER✔✔- The main purpose of Phase I
clinical trials is:


True - CORRECT ANSWER✔✔- The double-blind method means that both the doctors and
the patients are not informed of what is being administered, the true drug or the placebo.


True - CORRECT ANSWER✔✔- All life on earth is based on one genetic code.


G-C-C-A - CORRECT ANSWER✔✔- Which nucleotide sequence will be complimentary to
C-G-G-T?


The structure shown represents: - CORRECT ANSWER✔✔- Caffeine



Make a hypothesis. - CORRECT ANSWER✔✔- A scientist conducted experiments in which
she measured the amount of the vitamin, folic acid, in food after heating the food to various
temperatures. She graphed the data with temperature on one axis and folic acid content on the
other axis; she found a negative correlation. According to the scientific method, what should
be her next step?

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