Complete Solutions
2018 Guidlines - Group 1 ASCVD has been split into
subgroups, what are they? Correct Answer - Very high risk
- High risk
75% of myocardial infarctions occur due to rupture of plaques in
blood vessels that are ___ occluded. Correct Answer Less than
50%
A plaque is unstable due to ___. Correct Answer Inflammation
According to the new perspective on lipid goals, what should
evaluation/treatment be geared to? Correct Answer Global risk
assessment for ASCVD (atherosclerotic cardiovascular disease)
According to the new perspective on lipid goals, what trial
evidence shocked the medical community? Correct Answer No
RCT (clinical trials) evidence to support continued use of LDL
targets
Coronary Lesions: What are the characteristics of mild
obstruction? Correct Answer - No angina
- Unstable or soft plaques that are likely to rupture
Coronary Lesions: What are the characteristics of severe
obstruction? Correct Answer - Angina
- May never rupture
, Fibrates: What should be remembered with Fenofibrate?
Correct Answer Should not be used in patients with GFR less
than 30 mL/min
Fibrates: What should be remembered with Gemfibrozil?
Correct Answer NEVER give it with a statin, can be life-
threatening
Fibrates: When can Fenofibrate be considered for therapy?
Correct Answer If the patient is already using low- or moderate-
intensity statins
Group 1 - ASCVD High Risk: What is the treatment? Correct
Answer Ezetimibe in addition to high-intensity statin therapy
Group 1 - ASCVD Very High Risk: What is the treatment?
Correct Answer PCSK9 medication in addition to Ezetimibe
and high-intensity therapy
Group 1 - Established ASCVD: What is the first choice of
therapy? Correct Answer High-intensity for patient less than 75
years, moderate-intensity for patient than 75 years
Group 1 - Established ASCVD: What is the second choice of
therapy? Correct Answer Moderate-intensity for patients less
than 75 years, Individualized therapy for patient more than 75
years
Group 2 - Hyperlipidemia: If a patient also has elevated TGs
(triglycerides), what may be the cause? Correct Answer
Excessive alcohol intake