Cleavage
Cell Division – Cell Cycle Control
Morula – Compaction
Blastocyst – Hatching
Implantation – Decidual Reaction
Early Cell Lineages
Inner Cell Mass
Trophoblasts (Extra-embryonic)
Anomalies
,Cleavage
, Cleavage
Blastomere
Equal
Asynchronous
40 hours – 4 cells
72 hours – 6-12 cells
96 hours – 16-32 cells
, Cleavage – Molecular Events
In mammals – no large maternal stores of RNA
and ribosomes
Zygotic transcription begins by 2-4 cell stage
Oct-3 – Transcription factor expressed in egg
KO in mouse – arrest at 1 cell stage
Expressed in blastomeres up to morula stage
Expressed in germ cells
Cell Division – Cell Cycle Control
Morula – Compaction
Blastocyst – Hatching
Implantation – Decidual Reaction
Early Cell Lineages
Inner Cell Mass
Trophoblasts (Extra-embryonic)
Anomalies
,Cleavage
, Cleavage
Blastomere
Equal
Asynchronous
40 hours – 4 cells
72 hours – 6-12 cells
96 hours – 16-32 cells
, Cleavage – Molecular Events
In mammals – no large maternal stores of RNA
and ribosomes
Zygotic transcription begins by 2-4 cell stage
Oct-3 – Transcription factor expressed in egg
KO in mouse – arrest at 1 cell stage
Expressed in blastomeres up to morula stage
Expressed in germ cells
