PN3006 SKILLS INFO TEST

hemolytic reaction - ANSWER Occurs when there is destruction of
transfused red blood cells due to incompatibility (usually ABO mismatch)

onset minutes to hours

s/s:
fever
chills
back pain
dark urine

febrile reaction - ANSWER Non-hemolytic reaction caused by recipient
antibodies reacting to donor white blood cells.

onset usually minutes to hours
sometimes days to weeks after transfusion

s/s:
fever
chills

allergic reaction - ANSWER Mild reactions due to allergic response to
proteins in the transfused blood.

onset minutes to hours

s/s:
rash,
itching,
hives.

anaphylactic reaction - ANSWER Severe allergic reaction
often due to selective immunoglobulin A deficiency

onset minutes to hours

, s/s:
resp distress
hypotension
shock

circulatory overload (TACO) - ANSWER an excess in intravascular fluid
volume. causes pulmonary edema and resp distress. usually in pt with
heart or kidney conditions. can lead to heart failure.

onset minutes to hours

s/s:
crackles
HTN

sepsis - ANSWER Dangerous infection of the blood (blood transfusion
was infected)

onset minutes to hours

s/s:
high fever
chills
septic shock

transfusion related acute lung injury (TRALI) - ANSWER Leading cause
of transfusion related mortality
Non-cardiogenic pulmonary edema caused by donor antibodies reacting
with recipient's white cells

onset mins to hours

s/s:
acute resp distress
hypoxemia

don PPE order - ANSWER gown, mask, goggles, gloves