NR 567 RECOMMENDED QUESTIONS AND ANSWERS GOOD FOR FINAL EXAM REVISION

NR 567 RECOMMENDED
QUESTIONS AND ANSWERS GOOD
FOR FINAL EXAM REVISION
What is the therapeutic dosing of warfarin/coumadin?
5-10mg
What is the reversal agent for warfarin/coumadin?
Vitamin K
Labs that are used to monitor Warfarin/Coumadin?
PT and INR
What are the different typed of anticoagulants?
Oral Direcrt Factor Xa Inhibitors (DOAC)
Direct Thrombin Inhibitors
Fibrinolytics
Antiplatelets
What are oral direct factor Xa (DOAC) meds?
Rivaroxaban/Xarelto
Apixaban/Eliquis
Edoxaban
Action of oral direct factor Xa inhibitors?
(Rivaroxaban/Xarelto

,Apixaban/Eliquis
Edoxaban)
Inhibit factor Xa
Indications for use of oral direct factor Xa inhibitors?
(Rivaroxaban/Xarelto
Apixaban/E
Stroke
PE
DVT
What are the direct thrombin inhibitor meds?
Hirudin/Lepirudin (found in leech saliva)
Bivalirudin
Argatroban
Action of direct thrombin inhibitors?
(Hirudin/Lepirudin (found in leech saliva)
Bivalirudin
Argatroban)
reaches and inactivates fibrin bound thrombin
Indications for use of direct thrombin inhibitors?
(Hirudin/Lepirudin (found in leech saliva)
Bivalirudin
Argatroban)
Prevention in surgery

, What are the fibrinolytic meds?
Tissue plasminogen activators (t-PA)
Reteplase
Tenecteplase
Actions of fibrinolytic meds?
(Tissue plasminogen activators (t-PA)
Reteplase
Tenecteplase)
Rapidly lyse thrombi by catalyzing the formation of plasmin
from plasminogen.
Indications for use of fibrinolytic meds?
(Tissue plasminogen activators (t-PA)
Reteplase
Tenecteplase)
PE
DVT
thrombophlebitis
acute ischemic stroke (within 3 hours of symptom onset)
What are the antiplatelet meds?
Aspirin
Clopidogrel/Plavix
Actions of asprin?
inhibits synthesis of thromboxane