BSN 315 Pharm II Week 12 Antivirals
Exam Questions With 100% Correct
Answers
AntiviraliandiAntiretroviraliTherapy
Oseltamiviriisiapprovediforitheipreventionianditreatmentiofiinfluenzaiini
personsi1iyeariandiolder.iTheidrugiinhibitsiviralireplicationiandishortensi
durationiofiinfluenza.iItishouldibeistartediwithini48ihoursiofiinfluenzaisy
mptoms.
PatientiSafety
Hydrationiisiimportantiwhileitakingioseltamivir.i-iCorrectiAnswer-
Acycloviriisiaisyntheticipurineinucleosideianalogiandiisitheidrugiofichoice
itoitreatiinfectionsicausedibyimembersiofitheiherpesvirusifamily.
AcycloviriinhibitsiviraliDNAisynthesis.iItialsoiinhibitsitheiactivityiofiHSV-
1iHSV-2,iandivaricellaizoster.
Acycloviriisiuseditoitreatiencephalitis,iherpesigenitalisiandilabialis,iherp
esizoster,ivaricella,iandicomplicatediinfectioniwithiherpesisimplexivirus.
RibaviriniisianiantiviraliwhichiisiactiveiagainstimanyiDNAiandiRNAiviruse
s.iItiisieffectiveiinitreatingiRSViandichroniciHCVi(hepatitisiC).iRibavirinise
questerediinierythrocytesiremainsiinitheisystemiforiweeks.i-
iCorrectiAnswer-
LamivudineiisieffectiveiagainstichroniciHBV.iTheigoalsiofipharmacologici
treatmentiofihepatitisiwithiantiviralsiareitoireduceiorisuppressiliveriinfla
mmation,itherebyidecreasingitheiprogressionitoicirrhosisiandiitsicompli
,cations.iLamivudineiinhibitsireverseitranscriptase,iwhichipreventsivirusi
cellsifromireplicating.
Questioni1iofi4
Whichistatementiisiaccurateiwithirespectitoitheigoaliofiantiviralitreatme
ntiforiviralihepatitisiBi(HBV)?
Toireduceiorisuppressiliveriinflammation
ToikillialliHBV
Toienhanceitheipatient'siimmuneisystem
ToisequesteriHBViforieliminationi-iCorrectiAnswer-
Toireduceiorisuppressiliveriinflammation
Theigoaliofiantiviralitreatmentiisitoireduceiorisuppressiliveriinflammatio
n,itherebyidecreasingitheiprogressionitoicirrhosisiandiitsicomplications.
Questioni2iofi4
Foriwhichimedicaliconditioniwouldiinhalediribavirinibeiappropriate?
Influenza
ViralihepatitisiCi(HCV)
Respiratoryisyncytialivirusi(RSV)
Herpesizosteri-iCorrectiAnswer-Respiratoryisyncytialivirusi(RSV)
InhalediribaviriniisiindicatediforiRSV.
Questioni3iofi4
, Theinurseiplansitoiadministerioraliacyclovirieveryi4itoi5ihoursiforiherpesi
zosteribecauseiacyclovirihasiwhichihalf-life?
1itoi2ihours
2itoi4ihours
6itoi8ihours
10itoi12ihoursi-iCorrectiAnswer-2itoi4ihours
Acyclovirihasiaihalf-lifeiofi2itoi4ihours.
Questioni4iofi4
Whichiantiviralidrugiwouldibeiprescribeditoiaipatientiwhoihasigenitalihe
rpesisimplex?
Oseltamivir
Ribavirin
Lamivudine
Acycloviri-iCorrectiAnswer-Acyclovir
Acycloviriisiindicatediforiherpesigenitalis.
AbacaviriisiindicatediforiHIViinfectioniandiprophylacticallyiafterioccupat
ionaliHIViexposure.
abacaviriinhibitsireverseitranscriptase,ianienzymeineededibyitheiHIVitoir
eplicateiitself.i-iCorrectiAnswer-
Efavirenzibindsitoiandilaterialtersireverseitranscriptase,ianienzymeineed
edibyitheiHIVitoireplicateiitself.
Exam Questions With 100% Correct
Answers
AntiviraliandiAntiretroviraliTherapy
Oseltamiviriisiapprovediforitheipreventionianditreatmentiofiinfluenzaiini
personsi1iyeariandiolder.iTheidrugiinhibitsiviralireplicationiandishortensi
durationiofiinfluenza.iItishouldibeistartediwithini48ihoursiofiinfluenzaisy
mptoms.
PatientiSafety
Hydrationiisiimportantiwhileitakingioseltamivir.i-iCorrectiAnswer-
Acycloviriisiaisyntheticipurineinucleosideianalogiandiisitheidrugiofichoice
itoitreatiinfectionsicausedibyimembersiofitheiherpesvirusifamily.
AcycloviriinhibitsiviraliDNAisynthesis.iItialsoiinhibitsitheiactivityiofiHSV-
1iHSV-2,iandivaricellaizoster.
Acycloviriisiuseditoitreatiencephalitis,iherpesigenitalisiandilabialis,iherp
esizoster,ivaricella,iandicomplicatediinfectioniwithiherpesisimplexivirus.
RibaviriniisianiantiviraliwhichiisiactiveiagainstimanyiDNAiandiRNAiviruse
s.iItiisieffectiveiinitreatingiRSViandichroniciHCVi(hepatitisiC).iRibavirinise
questerediinierythrocytesiremainsiinitheisystemiforiweeks.i-
iCorrectiAnswer-
LamivudineiisieffectiveiagainstichroniciHBV.iTheigoalsiofipharmacologici
treatmentiofihepatitisiwithiantiviralsiareitoireduceiorisuppressiliveriinfla
mmation,itherebyidecreasingitheiprogressionitoicirrhosisiandiitsicompli
,cations.iLamivudineiinhibitsireverseitranscriptase,iwhichipreventsivirusi
cellsifromireplicating.
Questioni1iofi4
Whichistatementiisiaccurateiwithirespectitoitheigoaliofiantiviralitreatme
ntiforiviralihepatitisiBi(HBV)?
Toireduceiorisuppressiliveriinflammation
ToikillialliHBV
Toienhanceitheipatient'siimmuneisystem
ToisequesteriHBViforieliminationi-iCorrectiAnswer-
Toireduceiorisuppressiliveriinflammation
Theigoaliofiantiviralitreatmentiisitoireduceiorisuppressiliveriinflammatio
n,itherebyidecreasingitheiprogressionitoicirrhosisiandiitsicomplications.
Questioni2iofi4
Foriwhichimedicaliconditioniwouldiinhalediribavirinibeiappropriate?
Influenza
ViralihepatitisiCi(HCV)
Respiratoryisyncytialivirusi(RSV)
Herpesizosteri-iCorrectiAnswer-Respiratoryisyncytialivirusi(RSV)
InhalediribaviriniisiindicatediforiRSV.
Questioni3iofi4
, Theinurseiplansitoiadministerioraliacyclovirieveryi4itoi5ihoursiforiherpesi
zosteribecauseiacyclovirihasiwhichihalf-life?
1itoi2ihours
2itoi4ihours
6itoi8ihours
10itoi12ihoursi-iCorrectiAnswer-2itoi4ihours
Acyclovirihasiaihalf-lifeiofi2itoi4ihours.
Questioni4iofi4
Whichiantiviralidrugiwouldibeiprescribeditoiaipatientiwhoihasigenitalihe
rpesisimplex?
Oseltamivir
Ribavirin
Lamivudine
Acycloviri-iCorrectiAnswer-Acyclovir
Acycloviriisiindicatediforiherpesigenitalis.
AbacaviriisiindicatediforiHIViinfectioniandiprophylacticallyiafterioccupat
ionaliHIViexposure.
abacaviriinhibitsireverseitranscriptase,ianienzymeineededibyitheiHIVitoir
eplicateiitself.i-iCorrectiAnswer-
Efavirenzibindsitoiandilaterialtersireverseitranscriptase,ianienzymeineed
edibyitheiHIVitoireplicateiitself.
