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MICROBIOLOGY TEST QUESTIONS AND THEIR 100 % CORRECT ANSWERS

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A big reason as to why HIV thus far cannot be cured is that it? a. Is a retrovirus b. Contains a viral envelope c. Contains integrase d. Contains a protease c. contains integrase An infectious particle with an RNA genome and no capsid is known as a... viroid Which of the following is NOT a reason why antiviral agents are hard to develop? a. Because virus genomes are so small, there are relatively few molecules that can be used as drug targets. b. Antiviral agents usually have severe side effects because viral replication involves many host cell processes. c. To destroy the virus, the host cell must also be destroyed. d. Drug-resistant strains develop rapidly because viruses mutate quickly within the host. c. to destroy the virus, the host cell must also be destroyed. Which of the following statements regarding the minimum inhibitory concentration (MIC) is FALSE? a. The MIC is the same for one drug regardless of bacterial species b. The MIC is the lowest concentration of a drug that will prevent the growth of an organism c. The MIC can be affected by how well a drug penetrates a cell d. The MIC can be affected by the affinity of the drug for the intracellular target a. the MIC is the same for one drug regardless of bacterial species Drug A has a toxic dose of 17g/kg of body weight and a therapeutic dose of 8g/kg of body weight. Drug B has a toxic dose of 6 g/kg of body weight and a therapeutic dose of 4 g/kg of body weight. Which of the following statements is true? a. Drug B is the safer drug. b. Drug A is the safer drug. c. Drug B has a higher therapeutic index. d. Drug A has a lower therapeutic index. b. drug A is the safer drug Which of the following will result from inhibited topoisomerases? a. No cell wall synthesis b. Deficient plasma membrane c. Impaired DNA synthesis d. Impaired RNA synthesis c. impaired DNA synthesis Aminoglycosides inhibit translation by binding to the... 30S subunit All viruses contain a. genomic material b. capsid c. envelope d. all of the above e. a and b e. a and b; genomic material and capsid If 100% of the DNA contents of a transducing bacteriophage were DNA from the host chromosome, what would happen when the bacteriophage infected a new bacterial cell? a. more bacteriophage would be synthesized, resulting in death of the new bacterial cell b. no more bacteriophage would be synthesized, as there is no bacteriophage genome available to direct synthesis c. the new bacterial cell would die d. the bacteriophage would be converted from a lysogenic phage to a lytic bacteriophage b. no more bacteriophage would be synthesized, as there is no bacteriophage genome available to direct synthesis A small subset of the human population does not express the CD4 and CCR5 receptors. To what virus are these individuals naturally immune? a. HIV b. HPV

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MICROBIOLOGY TEST QUESTIONS
AND THEIR 100 % CORRECT
ANSWERS
A big reason as to why HIV thus far cannot be cured is that it?
a. Is a retrovirus
b. Contains a viral envelope
c. Contains integrase
d. Contains a protease
c. contains integrase
An infectious particle with an RNA genome and no capsid is
known as a...
viroid
Which of the following is NOT a reason why antiviral agents
are hard to develop?
a. Because virus genomes are so small, there are relatively few
molecules that can be used as drug targets.
b. Antiviral agents usually have severe side effects because
viral replication involves many host cell processes.
c. To destroy the virus, the host cell must also be destroyed.
d. Drug-resistant strains develop rapidly because viruses
mutate quickly within the host.
c. to destroy the virus, the host cell must also be destroyed.

,Which of the following statements regarding the minimum
inhibitory concentration (MIC) is FALSE?
a. The MIC is the same for one drug regardless of bacterial
species
b. The MIC is the lowest concentration of a drug that will
prevent the growth of an organism
c. The MIC can be affected by how well a drug penetrates a
cell
d. The MIC can be affected by the affinity of the drug for the
intracellular target
a. the MIC is the same for one drug regardless of bacterial
species
Drug A has a toxic dose of 17g/kg of body weight and a
therapeutic dose of 8g/kg of body weight.
Drug B has a toxic dose of 6 g/kg of body weight and a
therapeutic dose of 4 g/kg of body weight.
Which of the following statements is true?
a. Drug B is the safer drug.
b. Drug A is the safer drug.
c. Drug B has a higher therapeutic index.
d. Drug A has a lower therapeutic index.
b. drug A is the safer drug
Which of the following will result from inhibited
topoisomerases?
a. No cell wall synthesis
b. Deficient plasma membrane

, c. Impaired DNA synthesis
d. Impaired RNA synthesis
c. impaired DNA synthesis
Aminoglycosides inhibit translation by binding to the...
30S subunit
All viruses contain
a. genomic material
b. capsid
c. envelope
d. all of the above
e. a and b
e. a and b; genomic material and capsid
If 100% of the DNA contents of a transducing bacteriophage
were DNA from the host chromosome, what would happen
when the bacteriophage infected a new bacterial cell?
a. more bacteriophage would be synthesized, resulting in
death of the new bacterial cell
b. no more bacteriophage would be synthesized, as there is no
bacteriophage genome available to direct synthesis
c. the new bacterial cell would die
d. the bacteriophage would be converted from a lysogenic
phage to a lytic bacteriophage
b. no more bacteriophage would be synthesized, as there is no
bacteriophage genome available to direct synthesis

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