FIRST PUBLISH OCTOBER 2024
FSHN 350 Final Exam Study Guide Solutions
Energy imbalance: - Ans:✔✔-An excess of energy intake relative to energy expenditure will lead to
energy storage, where as a deficit of energy intake relative to expenditure will lead to loss of body
energy stores
NEAT: - Ans:✔✔-energy expenditure resulting from physical activity/movement that is not considered
exercise
PAEE- physical activity energy expenditure - Ans:✔✔-Exercise and NEAT
Thermic effect of food - Ans:✔✔-The increase in energy expenditure above RMR in response to the
ingestion of food. Accounts for 5-10% of calories ingested.
Basal or resting metabolic rate - Ans:✔✔-Energy expenditure by an individual for cellular processes
necessary to maintain life without activity 65-75%
Total daily energy expenditure: - Ans:✔✔-Made up of TEF and basal metabolic rate
Experiment #1 - Ans:✔✔-- DB mouse to wild type
-Normal mouse starved because DB mouse was secreting so much leptin, because it's deficient in leptin
receptors, that it causes the wild type mouse to starve
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Experiment #2 - Ans:✔✔-- DB mouse to OB mouse
-Ob mouse starves to death, because Ob mouse was leptin deficient
Experiment #3 - Ans:✔✔--Ob mouse to wild type
-Ob mouse saw decreased food intake, blood sugar and insulemia and the wild type mouse saw no
change
Levels of leptin in obese: - Ans:✔✔-Obese individuals have higher levels of leptin, due to development of
leptin resistance
What was the impact of the discovery of leptin? - Ans:✔✔-1. Changed prevail about obesity, from being
caused by a lack of will power to an imbalance of hormone signaling
2. Showed that adipose tissue is not just a useless and unwanted fat storage sight but rather an
endocrine organ
Orexogenic hormone - Ans:✔✔-Ghrelin, causes people to eat
Satiety factor: - Ans:✔✔-Leptin and PYY, signal brain to stop eating
PYY - Ans:✔✔-Released in the GI tract in response to ingested nutrients
Ghrelin: - Ans:✔✔-Appetite activating hormone found primarily in the stomach and duodenum,
increasing with fasting, central and peripheral administration increase food intake and body weight
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