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FSHN 350 Final Exam Study Guide Solutions

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FSHN 350 Final Exam Study Guide Solutions Energy imbalance: - Ans:-An excess of energy intake relative to energy expenditure will lead to energy storage, where as a deficit of energy intake relative to expenditure will lead to loss of body energy stores NEAT: - Ans:-energy expenditure resulting from physical activity/movement that is not considered exercise PAEE- physical activity energy expenditure - Ans:-Exercise and NEAT Thermic effect of food - Ans:-The increase in energy expenditure above RMR in response to the ingestion of food. Accounts for 5-10% of calories ingested. Basal or resting metabolic rate - Ans:-Energy expenditure by an individual for cellular processes necessary to maintain life without activity 65-75% Total daily energy expenditure: - Ans:-Made up of TEF and basal metabolic rate Experiment #1 - Ans:-- DB mouse to wild type -Normal mouse starved because DB mouse was secreting so much leptin, because it's deficient in leptin receptors, that it causes the wild type mouse to starve ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 2/13 Experiment #2 - Ans:-- DB mouse to OB mouse -Ob mouse starves to death, because Ob mouse was leptin deficient Experiment #3 - Ans:--Ob mouse to wild type -Ob mouse saw decreased food intake, blood sugar and insulemia and the wild type mouse saw no change Levels of leptin in obese: - Ans:-Obese individuals have higher levels of leptin, due to development of leptin resistance What was the impact of the discovery of leptin? - Ans:-1. Changed prevail about obesity, from being caused by a lack of will power to an imbalance of hormone signaling 2. Showed that adipose tissue is not just a useless and unwanted fat storage sight but rather an endocrine organ Orexogenic hormone - Ans:-Ghrelin, causes people to eat Satiety factor: - Ans:-Leptin and PYY, signal brain to stop eating PYY - Ans:-Released in the GI tract in response to ingested nutrients Ghrelin: - Ans:-Appetite activating hormone found primarily in the stomach and duodenum, increasing with fasting, central and peripheral administration increase food intake and body weight ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 3/13 Leptin: - Ans:-Positively correlated with adipose tissue mass and body weight, causes weight loss if injected in some indivudals How does leptin affect the brain? - Ans:-It activates POMC and inhibits Neuropeptide Y How does Ghrelin affect the brain? - Ans:-Activates Neuropeptide Y How does PYY affect the brain? - Ans:-Inhibits neuropeptide Y Neuropeptide Y - Ans:-Tells the brain to keep eating POMC - Ans:-Tells the brain to stop eating Why is it hard to to maintain weight loss? - Ans:-G

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©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED

FIRST PUBLISH OCTOBER 2024




FSHN 350 Final Exam Study Guide Solutions


Energy imbalance: - Ans:✔✔-An excess of energy intake relative to energy expenditure will lead to

energy storage, where as a deficit of energy intake relative to expenditure will lead to loss of body

energy stores


NEAT: - Ans:✔✔-energy expenditure resulting from physical activity/movement that is not considered

exercise


PAEE- physical activity energy expenditure - Ans:✔✔-Exercise and NEAT


Thermic effect of food - Ans:✔✔-The increase in energy expenditure above RMR in response to the

ingestion of food. Accounts for 5-10% of calories ingested.


Basal or resting metabolic rate - Ans:✔✔-Energy expenditure by an individual for cellular processes

necessary to maintain life without activity 65-75%


Total daily energy expenditure: - Ans:✔✔-Made up of TEF and basal metabolic rate


Experiment #1 - Ans:✔✔-- DB mouse to wild type


-Normal mouse starved because DB mouse was secreting so much leptin, because it's deficient in leptin

receptors, that it causes the wild type mouse to starve


Page 1/13

, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED

FIRST PUBLISH OCTOBER 2024




Experiment #2 - Ans:✔✔-- DB mouse to OB mouse


-Ob mouse starves to death, because Ob mouse was leptin deficient


Experiment #3 - Ans:✔✔--Ob mouse to wild type


-Ob mouse saw decreased food intake, blood sugar and insulemia and the wild type mouse saw no

change


Levels of leptin in obese: - Ans:✔✔-Obese individuals have higher levels of leptin, due to development of

leptin resistance


What was the impact of the discovery of leptin? - Ans:✔✔-1. Changed prevail about obesity, from being

caused by a lack of will power to an imbalance of hormone signaling


2. Showed that adipose tissue is not just a useless and unwanted fat storage sight but rather an

endocrine organ


Orexogenic hormone - Ans:✔✔-Ghrelin, causes people to eat


Satiety factor: - Ans:✔✔-Leptin and PYY, signal brain to stop eating


PYY - Ans:✔✔-Released in the GI tract in response to ingested nutrients


Ghrelin: - Ans:✔✔-Appetite activating hormone found primarily in the stomach and duodenum,

increasing with fasting, central and peripheral administration increase food intake and body weight

Page 2/13

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