©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
NBME 28 Exam Questions and Answers
Unconscious prioprioception mediated by what - Ans:✔✔-Cerebellum
Supination of forearm by what muscle - Ans:✔✔-Biceps brachii
Aminoglycosides work synergistically with what antibiotic class? - Ans:✔✔-Penicillins
Lesion demonstrating asymmetry, irregular borders, variable coloration, diameter greater than 6mm,
rapid evolution and biopsy showing atypical melanocytes spread along the basilar layer of the epidermis
- Ans:✔✔-Lentigo maligna a subtype of malignant melanoma
Protein C inactivates which factors? - Ans:✔✔-Factors V and VIII
Directly responsible for concentrating testosterone in the lumen of seminiferous tubules - Ans:✔✔-
Androgen-binding protein produced by Sertoli cells via FSH
Falling on outstretched hand with concurrent pain on palpation over the anatomic snuff box - Ans:✔✔-
Fracture of scaphoid which may lead to a vascular necrosis of proximal fragment and radial wrist pain
Most common location of colonic diverticula - Ans:✔✔-Sigmoid colon
Page 1/10
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Biopsy showing malignant, small dark blue tumor cells lacking nucleoli with a high nuclear:cytoplasm
ratio and expressing cytokeratin, chromogranin, and synaptophysin - Ans:✔✔-Pulmonary small cell
carcinoma; may be associated with paraneoplastic syndromes
Mechanism of regeneration of hepatocytes and renal tubular epithelial cells - Ans:✔✔-Recruitment of
quiescent cells from G0 into the cell cycle
Normal S1, widely split S2 that does not change with respiration, grade 3/6 holosystolic murmur that is
loudest at the lower left eternal border and radiates to the upper left eternal border - Ans:✔✔-Atrial
septal defect
Cell cycle phase where DNA replication occurs - Ans:✔✔-S phase
Cell cycle phase where enzymes necessary for DNA replication occurs - Ans:✔✔-G1 phase
MOA of metformin - Ans:✔✔-Inhibits hepatic gluconeogenesis and increases glucose uptake in
peripheral tissues (peripheral sensitivity to insulin)
Ovarian tumor associated with decreased serum concentrations of gonadotropins and marked increase
in circulating estrogens - Ans:✔✔-Granulosa cell tumorsok
Hardy Weinberg for X-linked diseases - Ans:✔✔-Frequency of affected males = q
Most common malignancy that metastasizes to liver - Ans:✔✔-Colonic CA
Page 2/10
FIRST PUBLISH OCTOBER 2024
NBME 28 Exam Questions and Answers
Unconscious prioprioception mediated by what - Ans:✔✔-Cerebellum
Supination of forearm by what muscle - Ans:✔✔-Biceps brachii
Aminoglycosides work synergistically with what antibiotic class? - Ans:✔✔-Penicillins
Lesion demonstrating asymmetry, irregular borders, variable coloration, diameter greater than 6mm,
rapid evolution and biopsy showing atypical melanocytes spread along the basilar layer of the epidermis
- Ans:✔✔-Lentigo maligna a subtype of malignant melanoma
Protein C inactivates which factors? - Ans:✔✔-Factors V and VIII
Directly responsible for concentrating testosterone in the lumen of seminiferous tubules - Ans:✔✔-
Androgen-binding protein produced by Sertoli cells via FSH
Falling on outstretched hand with concurrent pain on palpation over the anatomic snuff box - Ans:✔✔-
Fracture of scaphoid which may lead to a vascular necrosis of proximal fragment and radial wrist pain
Most common location of colonic diverticula - Ans:✔✔-Sigmoid colon
Page 1/10
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Biopsy showing malignant, small dark blue tumor cells lacking nucleoli with a high nuclear:cytoplasm
ratio and expressing cytokeratin, chromogranin, and synaptophysin - Ans:✔✔-Pulmonary small cell
carcinoma; may be associated with paraneoplastic syndromes
Mechanism of regeneration of hepatocytes and renal tubular epithelial cells - Ans:✔✔-Recruitment of
quiescent cells from G0 into the cell cycle
Normal S1, widely split S2 that does not change with respiration, grade 3/6 holosystolic murmur that is
loudest at the lower left eternal border and radiates to the upper left eternal border - Ans:✔✔-Atrial
septal defect
Cell cycle phase where DNA replication occurs - Ans:✔✔-S phase
Cell cycle phase where enzymes necessary for DNA replication occurs - Ans:✔✔-G1 phase
MOA of metformin - Ans:✔✔-Inhibits hepatic gluconeogenesis and increases glucose uptake in
peripheral tissues (peripheral sensitivity to insulin)
Ovarian tumor associated with decreased serum concentrations of gonadotropins and marked increase
in circulating estrogens - Ans:✔✔-Granulosa cell tumorsok
Hardy Weinberg for X-linked diseases - Ans:✔✔-Frequency of affected males = q
Most common malignancy that metastasizes to liver - Ans:✔✔-Colonic CA
Page 2/10
