FIRST PUBLISH OCTOBER 2024
AHN 554 Mod 2-GI Exam Study Guide
2024
Causes of severe aminotransferase elevations > 15xnormal - Ans:✔✔-Acute viral hepatits (A-E, herpes)
Meds/toxins
Ischemic or Autoimmune hepatitis
Wilson disease
Acute bile duct obstruction
Acute Budd Chiari syndrome
Hepatic a. ligation
EUS - endoscopic ultrasonography - Ans:✔✔-most sensitive test for detecting small lesions of the
ampulla or pancreatic head and for detecting portal vein invasion by pancreatic cancer. It is also accurate
for detecting or excluding bile duct stones.
Hep A - essentials of dx - Ans:✔✔-Prodrome of anorexia, N/V, malaise, aversion to smoking.
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FIRST PUBLISH OCTOBER 2024
Fever, enlarged and tender liver, jaundice
Norm to low WBC, markedly elevated aminotransferases
Hep A virus transmission - Ans:✔✔-fecal oral route
person to person or contaminated food/water
Acute Hep B essentials of dx - Ans:✔✔-prodrome of anorexia, N/V malaise, aversion to smoking
Fever, enlarged and tender liver, jaundice
Norm to low WBC, markedly elevated aminotransferases early in the course
Liver bx - hepatocellular necrosis and monomuclear infiltrate, but is rarely indicated.
Hep B transmission - Ans:✔✔-blood or blood products
sexual -saliva, semen and vaginal secretions.
HBsAg pos mothers may transmit at delivery - high risk of chronic infection in infant.
HBsAg - Ans:✔✔-first evidence of infection, appears before biochemical evidence of liver dx, persists
through clinical illness.
Persistence for more than 6 months after acute illness signifies Chronic hep B
Anti-HBc - Ans:✔✔-IgM anti-HBc appears shortly after HBsAg is detected.
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, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Indicates acute Hepatitis B
Can persists for 3-6 mo or longer
HAV IgM - Ans:✔✔-acute infection - peak at 1st week of clinical dx and disappear w/in 3-6 mo.
HAV IgG - Ans:✔✔-hepatitis A recovery or vaccination - "gone"
HEV IgM - Ans:✔✔-acute Hep E
HEV IgG - Ans:✔✔-recovery of Hep E
HBeAg - Ans:✔✔-Active viral replication and infectivity
Most common cause of vital hepatitis world wide - Ans:✔✔-Hep A
Clinical signs and symptoms of appendicitis - Ans:✔✔-Early - vague, colicky periumbilical or epigastric
pain. W/in 12 hrs - pain shifts to RLQ - steady ache worsened by walking or coughing.
Assoc: nausea w/ 1-2 episodes of vomiting.
(Protracted vomiting, or vomiting before pain suggests alt dx.)
-Sense of constiaption, some diarrhea.
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