©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
AHN 577 heme/onc Exam Study Guide 2024
Normal Hgb - Ans:✔✔-Men: 14-18
Women: 12-16
Normal MCV range - Ans:✔✔-80-100 fL
-This is where the "-cytic" comes from
normal MCH values - Ans:✔✔-27-34
- This is where the "-chromic" comes from
normal MCHC values - Ans:✔✔-32-36 g/dL
normal TIBC levels - Ans:✔✔-250-450
normal iron range - Ans:✔✔-50-150 mcg/dL
Normal ferritin levels - Ans:✔✔-12-100ng/ml
megaloblastic hyperchromic anemia - Ans:✔✔-B12 Deficient
Pernicious Anemia
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, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Megaloblastic normochromic anemia - Ans:✔✔-Folate deficiency
normocytic normochromic anemia - Ans:✔✔-Anemia of chronic disease
microcytic hypochromic anemia - Ans:✔✔-anemia characterized by small, pale red blood cells that lack
adequate hemoglobin to carry oxygen; can be caused by deficiency of iron or vitamin B6
- Thalassemias
S/S of pernicious anemia - Ans:✔✔-glossitis, paresthesia, loss of vibratory sense, loss of fine motor, +
rhomberg, +babinski
- splenomegaly
Testing for pernicious anemia - Ans:✔✔-Anti-IF and Anti-parietal cell antibodies
-Schilling test to differentiate pernicious anemia from isolated B12 deficiency
Other causes of B12 deficiency that are NOT pernicious anemia - Ans:✔✔--Metformin
-Etoh
-Diet
-Hemodialysis
-Tapeworms
Page 2/25
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
-Malabsorption from GI surgeries
Lab Ranges for serum Folate - Ans:✔✔-<2ng/ml is diagnostic
if >4ng/ml can rule out folate deficiency
Drugs that can cause folate deficiency - Ans:✔✔--Methotrexate
-Pyrimethamine
-etoh
-phenytoin
-isoniazid
-birth control
s/s of folate deficiency - Ans:✔✔--glossitis, mouth and tongue pain, hyperpigmentation, weight loss,
orthostatic hypotension
What kind of Anemia is iron deficiency anemia - Ans:✔✔-microcytic hypochromic
MCV for iron deficiency - Ans:✔✔-<80
MCHC for iron deficiency - Ans:✔✔-<32
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FIRST PUBLISH OCTOBER 2024
AHN 577 heme/onc Exam Study Guide 2024
Normal Hgb - Ans:✔✔-Men: 14-18
Women: 12-16
Normal MCV range - Ans:✔✔-80-100 fL
-This is where the "-cytic" comes from
normal MCH values - Ans:✔✔-27-34
- This is where the "-chromic" comes from
normal MCHC values - Ans:✔✔-32-36 g/dL
normal TIBC levels - Ans:✔✔-250-450
normal iron range - Ans:✔✔-50-150 mcg/dL
Normal ferritin levels - Ans:✔✔-12-100ng/ml
megaloblastic hyperchromic anemia - Ans:✔✔-B12 Deficient
Pernicious Anemia
Page 1/25
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Megaloblastic normochromic anemia - Ans:✔✔-Folate deficiency
normocytic normochromic anemia - Ans:✔✔-Anemia of chronic disease
microcytic hypochromic anemia - Ans:✔✔-anemia characterized by small, pale red blood cells that lack
adequate hemoglobin to carry oxygen; can be caused by deficiency of iron or vitamin B6
- Thalassemias
S/S of pernicious anemia - Ans:✔✔-glossitis, paresthesia, loss of vibratory sense, loss of fine motor, +
rhomberg, +babinski
- splenomegaly
Testing for pernicious anemia - Ans:✔✔-Anti-IF and Anti-parietal cell antibodies
-Schilling test to differentiate pernicious anemia from isolated B12 deficiency
Other causes of B12 deficiency that are NOT pernicious anemia - Ans:✔✔--Metformin
-Etoh
-Diet
-Hemodialysis
-Tapeworms
Page 2/25
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
-Malabsorption from GI surgeries
Lab Ranges for serum Folate - Ans:✔✔-<2ng/ml is diagnostic
if >4ng/ml can rule out folate deficiency
Drugs that can cause folate deficiency - Ans:✔✔--Methotrexate
-Pyrimethamine
-etoh
-phenytoin
-isoniazid
-birth control
s/s of folate deficiency - Ans:✔✔--glossitis, mouth and tongue pain, hyperpigmentation, weight loss,
orthostatic hypotension
What kind of Anemia is iron deficiency anemia - Ans:✔✔-microcytic hypochromic
MCV for iron deficiency - Ans:✔✔-<80
MCHC for iron deficiency - Ans:✔✔-<32
Page 3/25
