FIRST PUBLISH OCTOBER 2024
Biochemistry WGU c785 Exam Practice
Questions and Answers
Nonenzymatic glycosylation or glycation creates glycoproteins by:
1. Chemical addition of sugars to polypeptides
2. Extracellular synthesis
3. Attaching 20 amino acids
4. Secretion into extracellular matrix - Ans:✔✔-1
Nonenzymatic glycosylation or glycation creates glycoproteins by the chemical addition of sugars to
polypeptides. Since this type of glycosylation is nonenzymatic, the time and the concentration of sugar
control glycosylation. Because people with higher circulating levels of glucose have higher levels of
nonenzymatic glycosylation, measurement of the glycosylated hemoglobin A1c is a diagnostic test used
to monitor blood sugar levels in persons with diabetes.
Which of the following is a 5-carbon sugar?
1. Glucose
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2. Fructose
3. Ribose
4. Sucrose - Ans:✔✔-3
Ribose is a pentose, a simple sugar (monosaccharide) that has five carbon atoms per molecule. It is
synthesized in the body and obtained in small amounts from consumption of ripe fruits and vegetables.
Ribose serves as an energy substrate for the resynthesis of ATP and is a key component of ribonucleic
acid (RNA). Deoxyribose, a component of DNA, also is a pentose.
The optimum pH of pepsin is:
1. 5
2. 7.1
3. 8.1
4. 2 - Ans:✔✔-4
The optimum pH for enzymes varies for different enzymes and even enzymes with similar actions may
have different optimal pH based on where they act. For example, trypsin, a digestive enzyme that acts in
the small intestine has an optimal pH of 8 while pepsin, which acts in the more acidic milieu of the
stomach, has an optimal pH of 2.
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