FIRST PUBLISH OCTOBER 2024
BioChem C785 - Module 1 - all questions
with correct answers
DNA replication is semiconservative, which allows each of the 2 strands to serve as a template for the
new strands - Ans:✔✔-true
Recall that the DNA polymerase must bind a double-stranded polymer before it can start making its own
DNA polymer. What helps the DNA polymerase to overcome this problem in DNA replication? - Ans:✔✔-
RNA primers
Several components of cigarette smoke, including benzopyrene, insert themselves into the DNA and lead
to several types of mutations such as frameshift mutations, including both insertions and deletion.
Which repair pathway would be used to repair this type of damage? - Ans:✔✔-Nucleotide Excision
Repair
Maternal smoking during pregnancy is hazardous yet common in many places. Many studies have
associated prenatal smoking to unhealthy physical and psychological outcomes for the baby. Researchers
know that maternal smoking affects are epigenetic in nature. Which event can be considered epigenetic
in nature? - Ans:✔✔-Changes in chromatin structure
Blood is what type of inheritance? - Ans:✔✔-codominance
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What is the probability that a child will have an autosomal dominant disease if their father is
heterozygous for the allele and their mother is homozygous for the normal allelle? - Ans:✔✔-50%
What is the complementary DNA strand for the DNA sequence 5'-ATT CGG GCT CCC - 3' - Ans:✔✔-5'-
GGG AGC CCG AAT - 3'
A research scientist is trying to create a new strain of bacteria that can produce a protein needed for her
research. What molecule will act as a template in creating the new protein? - Ans:✔✔-messenger RNA
(mRNA)
What is 1 direct effect of inhibiting translation? - Ans:✔✔-the production of proteins would stop
How many amino acids, and which ones, would be encoded by the following mRNA sequence: 5'-
AUGACUCCCGGG -3' - Ans:✔✔-4: MET, THR, PRO, GLY
Promoters are DNA sequences near the start of a gene that are recognized by transcription factors which
recruit RNA polymerase to that gene for expression. This is an important aspect of transcriptions but not
part of the mRNA processing. - Ans:✔✔-true
You are designing a piece of DNA for a project and must select the appropriate nitrogenous bases. Which
combination of nitrogenous bases would you find most suitable for your work? - Ans:✔✔-Adenine,
Guanine, Thymine, Cytosine
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