©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
C785 Biochemistry preassessment Exam
Practice Questions and Answers
Assuming 100% reaction efficiency, how many DNA copies are created after the completion of four
complete PCR cycles? - Ans:✔✔-16
What is the function of DNA polymerase in the process of PCR? - Ans:✔✔-It recognizes the primers and
uses the available dNTPs to replicate the template DNA sequence.
What are possible blood types of the parents of a patient with blood type AB? - Ans:✔✔-A and B
115 116 117 118 − Amino Acid Number
Tyr Gly Thr Pro − Amino Acid Sequence
TAC GGG ACA CCA − DNA Sequence
What is the amino acid in position 118 that results from a single nucleotide insertion immediately
following the three guanines that encode for glycine 116? - Ans:✔✔-Thr
In sickle-cell disease, the glutamic acid (Glu) at position number seven is mutated to valine (Val).
Page 1/8
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
What change in codons corresponds to this mutation? - Ans:✔✔-GAA to GTA
Which type of mammalian DNA damage repair requires the presence of the chromosome that is
homologous to the damaged chromosome? - Ans:✔✔-Recombination
Xeroderma pigmentosum (XP) is a recessive genetic disease that occurs when one or more of the genes
that perform nucleotide excision repair are nonfunctional.
Why do XP patients have a much higher incidence of skin cancer than the general population? - Ans:✔✔-
The mutation rate of all other genes is higher due to failure to repair.
Which mRNA sequence results in a polypeptide that contains three amino acids? - Ans:✔✔-5' - CUU GAU
ACU UAG - 3'
Which template strand DNA sequence would result in the amino acid (Ser)? - Ans:✔✔-5' - CGA - 3'
What is the complementary sequence for the following DNA sequence?
5' - GCC ATC TCG AAT - 3' - Ans:✔✔-5' - ATT CGA GAT GGC - 3'
Page 2/8
FIRST PUBLISH OCTOBER 2024
C785 Biochemistry preassessment Exam
Practice Questions and Answers
Assuming 100% reaction efficiency, how many DNA copies are created after the completion of four
complete PCR cycles? - Ans:✔✔-16
What is the function of DNA polymerase in the process of PCR? - Ans:✔✔-It recognizes the primers and
uses the available dNTPs to replicate the template DNA sequence.
What are possible blood types of the parents of a patient with blood type AB? - Ans:✔✔-A and B
115 116 117 118 − Amino Acid Number
Tyr Gly Thr Pro − Amino Acid Sequence
TAC GGG ACA CCA − DNA Sequence
What is the amino acid in position 118 that results from a single nucleotide insertion immediately
following the three guanines that encode for glycine 116? - Ans:✔✔-Thr
In sickle-cell disease, the glutamic acid (Glu) at position number seven is mutated to valine (Val).
Page 1/8
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
What change in codons corresponds to this mutation? - Ans:✔✔-GAA to GTA
Which type of mammalian DNA damage repair requires the presence of the chromosome that is
homologous to the damaged chromosome? - Ans:✔✔-Recombination
Xeroderma pigmentosum (XP) is a recessive genetic disease that occurs when one or more of the genes
that perform nucleotide excision repair are nonfunctional.
Why do XP patients have a much higher incidence of skin cancer than the general population? - Ans:✔✔-
The mutation rate of all other genes is higher due to failure to repair.
Which mRNA sequence results in a polypeptide that contains three amino acids? - Ans:✔✔-5' - CUU GAU
ACU UAG - 3'
Which template strand DNA sequence would result in the amino acid (Ser)? - Ans:✔✔-5' - CGA - 3'
What is the complementary sequence for the following DNA sequence?
5' - GCC ATC TCG AAT - 3' - Ans:✔✔-5' - ATT CGA GAT GGC - 3'
Page 2/8
