©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
HEM.ONC exam 3 AHN 554 Study Guide
Lab findings associate with IDA - Ans:✔✔-decreased hg
decreased to normal MCV
increased RDW or normal
increased ferritin
decreased transferring saturation
decreased iron
HYPOchromic, MICROcytic
Normal RBC levels - Ans:✔✔-Males 4.7-6.1 million/mm3
Females 4.2-5.4 million/mm3
Normal MCV levels - Ans:✔✔-80-100fL
normal MCHC values - Ans:✔✔-32-36%- normochromic
Normal RDW range - Ans:✔✔-11.5-14.5%
Page 1/25
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Normal reticulocyte count - Ans:✔✔-1-2%
What are reticulocytes? - Ans:✔✔-immature RBCs
Vitamin B12 normal range - Ans:✔✔-above 300 pg/mL
Normal folate level - Ans:✔✔-above 4 ng/mL
What uncommon lab values are elevated in B12 deficiency? - Ans:✔✔-homocysteine- elevated
methylmalonic acid(MMA)- elevated
What uncommon lab value is elevated in folate deficiency? - Ans:✔✔-homocysteine- elevated
Normal ferritin levels - Ans:✔✔-40-200 mcg/L
Ferritin level in severe IDA? - Ans:✔✔-less than 12
normal iron level - Ans:✔✔-50-150 mcg/dL
Iron level in severe IDA? - Ans:✔✔-less than 40
TIBC normal range - Ans:✔✔-250-450 mcg/dL
What is transferrin? - Ans:✔✔-iron transport protein
Page 2/25
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
What is TIBC (Total Iron Binding Capacity) - Ans:✔✔-Measurement of transferrin iron binding capability
(1/3 of transferrin is typically bound with iron)
normal transferrin levels - Ans:✔✔-Measured as a saturation ratio- Iron/TIBC
normal 20-50%
Transferrin level in IDA? - Ans:✔✔-less than 15%
What is sideroblastic anemia? - Ans:✔✔--Hypochromic microocytic anemia (can be normocytic or
macrocytic)→ small size, lack of color
-Hereditary anemia characterized by inefficient iron uptake resulting in dysfunctional hemoglobin
synthesis
-Not able to process iron, doesn't get stored/reused
- Can be caused from chemo/radiation
- reversible if caused by alcohol, medications, thiamine deficiency and copper deficiency
What is aplastic anemia? - Ans:✔✔-- rare condition caused by failure of blood cell production due to
destruction of bone marrow cells
What can cause aplastic anemia? - Ans:✔✔-unknown but suspected from benzene, HIV, EBV,
sulfonamides, methimazole/PTU, SLE
Page 3/25
FIRST PUBLISH OCTOBER 2024
HEM.ONC exam 3 AHN 554 Study Guide
Lab findings associate with IDA - Ans:✔✔-decreased hg
decreased to normal MCV
increased RDW or normal
increased ferritin
decreased transferring saturation
decreased iron
HYPOchromic, MICROcytic
Normal RBC levels - Ans:✔✔-Males 4.7-6.1 million/mm3
Females 4.2-5.4 million/mm3
Normal MCV levels - Ans:✔✔-80-100fL
normal MCHC values - Ans:✔✔-32-36%- normochromic
Normal RDW range - Ans:✔✔-11.5-14.5%
Page 1/25
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Normal reticulocyte count - Ans:✔✔-1-2%
What are reticulocytes? - Ans:✔✔-immature RBCs
Vitamin B12 normal range - Ans:✔✔-above 300 pg/mL
Normal folate level - Ans:✔✔-above 4 ng/mL
What uncommon lab values are elevated in B12 deficiency? - Ans:✔✔-homocysteine- elevated
methylmalonic acid(MMA)- elevated
What uncommon lab value is elevated in folate deficiency? - Ans:✔✔-homocysteine- elevated
Normal ferritin levels - Ans:✔✔-40-200 mcg/L
Ferritin level in severe IDA? - Ans:✔✔-less than 12
normal iron level - Ans:✔✔-50-150 mcg/dL
Iron level in severe IDA? - Ans:✔✔-less than 40
TIBC normal range - Ans:✔✔-250-450 mcg/dL
What is transferrin? - Ans:✔✔-iron transport protein
Page 2/25
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
What is TIBC (Total Iron Binding Capacity) - Ans:✔✔-Measurement of transferrin iron binding capability
(1/3 of transferrin is typically bound with iron)
normal transferrin levels - Ans:✔✔-Measured as a saturation ratio- Iron/TIBC
normal 20-50%
Transferrin level in IDA? - Ans:✔✔-less than 15%
What is sideroblastic anemia? - Ans:✔✔--Hypochromic microocytic anemia (can be normocytic or
macrocytic)→ small size, lack of color
-Hereditary anemia characterized by inefficient iron uptake resulting in dysfunctional hemoglobin
synthesis
-Not able to process iron, doesn't get stored/reused
- Can be caused from chemo/radiation
- reversible if caused by alcohol, medications, thiamine deficiency and copper deficiency
What is aplastic anemia? - Ans:✔✔-- rare condition caused by failure of blood cell production due to
destruction of bone marrow cells
What can cause aplastic anemia? - Ans:✔✔-unknown but suspected from benzene, HIV, EBV,
sulfonamides, methimazole/PTU, SLE
Page 3/25
