©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
N115 Final Study Exam Questions and
Answers
Adverse effects of methylxanthines include all of the following except which one?
a. narrow therapeutic window and drug interactions
b. restlessness, insomnia
c. hepatic toxicity
d. nausea, vomiting, diarrhea - Ans:✔✔-ANS: C
Which of the following describes the mechanism of action of omalizumab (Xolair), a new asthma
treatment that must be injected subQ?
a. inhibit antigen-induced release of immunoglobulin E (IgE) from lung tissue
b. inhibition of phosphodiesterase and bronchodilation
Page 1/104
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
c. partial β-agonist activity results in smooth muscle relaxation
d. all of the above - Ans:✔✔-ANS: A
According to the current guidelines for the diagnosis and management of asthma, which one of the
following medications is the first choice 'rescue' bronchodilator in asthma exacerbations?
a. ipratropium [Atrovent], an antimuscarinic
b. albuterol [Ventolin], a beta 2 agonist
c. epinephrine [Adrenaline], a non-selective sympathomimetic
d. salmeterol [Serevent], a long-acting beta 2 agonist - Ans:✔✔-ANS: B
Which one of the following is FDA-approved only for COPD and not asthma?
a. albuterol [Ventolin], a beta 2 (b2 ) agonist
b. epinephrine [Adrenaline], a non-selective sympathomimetic
c. cromolyn [Intal], an anti-inflammatory agent
d. ipratropium [Atrovent], an antimuscarinic - Ans:✔✔-ANS: D
Page 2/104
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Which of the following is a common adverse effect of nasal decongestants?
a. tolerance with repeated use
b. restlessness, irritability, insomnia
c. rebound congestion
d. all of the above - Ans:✔✔-ANS: D
Which adverse effect is prominent with first-generation antihistamines?
a. antimuscarinic effects
b. nausea
c. dry cough
d. all of the above - Ans:✔✔-ANS: D
The leukotriene modifiermontelukast [Singulair] has which anti-inflammatory mechanism of action for
asthma treatment?
Page 3/104
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
a. inhibit leukotriene synthesis by blocking 5-lipooxygenase
b. block leukotriene effects by antagonist action at leukotriene D4 receptors
c. decreased synthesis of inflammatory mediators
d. suppresses histamine release - Ans:✔✔-ANS: B
Which of the following are true statements about long-acting beta2 agonists (LABA)?
a. May be taken in place of an inhaled corticosterioid
b. often given in combination with a short-acting beta2 agonists (SABA)
c. may be used to improve nighttime symptoms in asthma and COPD
d. may be used to prevent exercise-induced asthma - Ans:✔✔-ANS: C
Which of the following drug classes are used to treat both heart failure and hypertension?
1. ACE inhibitors
2. digoxin
Page 4/104
FIRST PUBLISH OCTOBER 2024
N115 Final Study Exam Questions and
Answers
Adverse effects of methylxanthines include all of the following except which one?
a. narrow therapeutic window and drug interactions
b. restlessness, insomnia
c. hepatic toxicity
d. nausea, vomiting, diarrhea - Ans:✔✔-ANS: C
Which of the following describes the mechanism of action of omalizumab (Xolair), a new asthma
treatment that must be injected subQ?
a. inhibit antigen-induced release of immunoglobulin E (IgE) from lung tissue
b. inhibition of phosphodiesterase and bronchodilation
Page 1/104
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
c. partial β-agonist activity results in smooth muscle relaxation
d. all of the above - Ans:✔✔-ANS: A
According to the current guidelines for the diagnosis and management of asthma, which one of the
following medications is the first choice 'rescue' bronchodilator in asthma exacerbations?
a. ipratropium [Atrovent], an antimuscarinic
b. albuterol [Ventolin], a beta 2 agonist
c. epinephrine [Adrenaline], a non-selective sympathomimetic
d. salmeterol [Serevent], a long-acting beta 2 agonist - Ans:✔✔-ANS: B
Which one of the following is FDA-approved only for COPD and not asthma?
a. albuterol [Ventolin], a beta 2 (b2 ) agonist
b. epinephrine [Adrenaline], a non-selective sympathomimetic
c. cromolyn [Intal], an anti-inflammatory agent
d. ipratropium [Atrovent], an antimuscarinic - Ans:✔✔-ANS: D
Page 2/104
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Which of the following is a common adverse effect of nasal decongestants?
a. tolerance with repeated use
b. restlessness, irritability, insomnia
c. rebound congestion
d. all of the above - Ans:✔✔-ANS: D
Which adverse effect is prominent with first-generation antihistamines?
a. antimuscarinic effects
b. nausea
c. dry cough
d. all of the above - Ans:✔✔-ANS: D
The leukotriene modifiermontelukast [Singulair] has which anti-inflammatory mechanism of action for
asthma treatment?
Page 3/104
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
a. inhibit leukotriene synthesis by blocking 5-lipooxygenase
b. block leukotriene effects by antagonist action at leukotriene D4 receptors
c. decreased synthesis of inflammatory mediators
d. suppresses histamine release - Ans:✔✔-ANS: B
Which of the following are true statements about long-acting beta2 agonists (LABA)?
a. May be taken in place of an inhaled corticosterioid
b. often given in combination with a short-acting beta2 agonists (SABA)
c. may be used to improve nighttime symptoms in asthma and COPD
d. may be used to prevent exercise-induced asthma - Ans:✔✔-ANS: C
Which of the following drug classes are used to treat both heart failure and hypertension?
1. ACE inhibitors
2. digoxin
Page 4/104
