NP Certification GI questions with correct answers

NP Certification GI questions with correct answers The gastric parietal cells produce? - Ans:-hydrochloric acid Antiprostaglandin drugs cause stomach mucosal injury primarily by? direct irritation altering thickness of protective mucosal layer decreasing peristalsis modifying pH levels - Ans:-altering thickness of protective mucosal layer for prevention of recurrence of duodenal ulcer in middle-aged man, prescribe? PPI antacid antimicrobial H2RA antimicrobial therapy - Ans:-antimicrobial therapy ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 2/8 H2RA most like interaction with cimetidine famotidine nizatidine ranitidine - Ans:-cimetidine (Tagamet) NSAID-induced PUD can best be limited by the use of? antacid H2RA ABX misoprostol - Ans:-misoprostol (cytotec) Which is a PPI loperamide metoclopramide nizatidine ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 3/8 lansoprazole - Ans:-lansoprazole which is a prostaglandin analog? sucralfate misoprostol esomeprazole Reglan - Ans:-misoprostol long-term PPI associated with all except? increased PNA risk for inpatients increased C. diff risk reduced Calcium and Magnesium reduced dietary carbs - Ans:-carbs to avoid rebound gastric hyperactivity following d/c of long-term PPI use, all of the following can be used except? taper PPI w/ antacid switch to every other day PPI w/antacid ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 4/8 switch to low dose H2RA w/ antacid empiric H. pylori therapy - Ans:-empiric H. pylori therapy Pt with symptomatic gastroesophageal reflux, you prescribe PPI to? enhance motility increase pH of stomach reduce LES pressure help limit H. pylori growth - Ans:-enhance pH (4.0) 38 yo nonsmoking male presents w/ s/s consistent w/ GERD, has self treated with OTC antacids and acid suppression therapy with effect. his wt is stable, and denies N/V/D or melena. Which of the following represents the most appropriate dx plan? fecal testing for H. pylori Upper GI barium swallow no specific test needed - Ans:-no specific test needed which of the following in most likely to be found in a 50 yr old woman w/ new onset reflux esophagitis? ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 5/8 recent initiation of estrogen-progestin hormonal therapy recent wt loss melena evidence of H. pylori - Ans:-estrogen-progestin 58 yo man recently began taking antihypertensive meds and reports "heartburn" has become worse. he is most likely taking? atenolol trandolapril amlodipine losartan - Ans:-amlodipine You prescribe fluoroquinolone ABX to a 54 yo woman who has occasional GERD symptoms that she treats w/ antacid. when discussing appropriate med use, you advise that she should take the ABX? w/ the antacid separated from antacid 2-4 hours before and 4-6 hours after ABX any time ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 6/8 apart from the antacid by 1 hour on either side of the ABX - Ans:-REVIEW book: 2-4 hours and 4-6 hours 48 yo man w/ obesity and 1 yr Hx of classic GERD symptoms has been on consistent use of therapeutic dose of PPI for 6 months. not better w/medication, cut out all alcohol and soda. Exam wt stable, mildly erythematous pharynx, epigastric tenderness w/o rebound. next step? GI series referral for GERD surgery further eval w/ upper GI obtain FOBT testing - Ans:-further eval w/ upper GI endoscopy which is not an alarm finding in a person w/ GERD