FIRST PUBLISH OCTOBER 2024
NU317 Exam #4 Study Guide with
Complete Solutions
three functions of kidneys - Ans:✔✔-urine formation, electrolyte/ BP balance, production of
erythropoietin
s/s of AKI - Ans:✔✔-decreased urine output, swelling in legs ankles and around eyes, fatigue, SOB,
confusion, nausea, chest pain or pressure, and seizures/ coma in severe cases
meds that affect kidney fxn - Ans:✔✔-NSAIDs, ARBs/ ACEi, diuretics, MRAs, metformin, antibiotics (ex:
vancomycin)
AKI anuric UOP - Ans:✔✔-less than 100 mL per day
AKI oliguric UOP - Ans:✔✔-less than 500 mL per day
AKI non-oliguric UOP - Ans:✔✔-more than 500 mL per day
what is a vital sign that may indicate that kidneys aren't profusing - Ans:✔✔-orthostatic vitals
pre-renal AKI - Ans:✔✔-hypovolemic states, hypervolemic states, hypotension, dysregulation of renal
vasculature
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acute glomerulonephritis - Ans:✔✔-hematuria, proteinurea, HTN, pyuria, hypoalbuminemia, edema,
HLD
acute tubular necrosis - Ans:✔✔-most common cause of AKI; often caused by prolonged or severe
ischemia or nephrotoxic exposure; can be associated with sepsis or shock, oliguria, inability to
concentrate urine
specific gravity levels - Ans:✔✔-1.005 dilute to 1.030 concentrated
acute interstitial nephritis - Ans:✔✔-often drug-induced, sterile pyuria, classic triad (fever, rash, and
serum eosinophilia)
renal vascular disease - Ans:✔✔-Impaired blood flow and renal ischemia activate the Renin-angiotensin-
aldosterone mechanism in an effort to raise renal perfusion pressure
Post-renal AKI causes - Ans:✔✔-Secondary to obstruction of urinary outflow
Usually no kidney damage
Reversible once obstruction resolved
post-renal AKI examples - Ans:✔✔-bladder outlet obstruction (cancer), kidney stones, metastatic cancer,
retroperitoneal fibrosis
causes of AKI in hospitalized patients - Ans:✔✔-45% is acute tubular necrosis and 21% is pre-renal AKI
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