©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
NUR 545 Final Exam Practice Questions
and Answers
Drug interaction for penicillin? - Ans:✔✔-o Aminoglycosides- don't mix penicillin with this drug. Penicillin
deactivates aminoglycoside.
MOA for penicillin? - Ans:✔✔-o disrupts bacterial cells wall which leads to cell death
Adverse effect of penicillin? - Ans:✔✔-o anaphylactic reaction (s/s: SOB, rash, angioedema). Give
epinephrine when this occurs.
High-risk patients for penicillin - Ans:✔✔-o The elderly or renal impairment (reduce the dose)
What's the cross-reactivity with penicillin (beta lactam ring)? - Ans:✔✔-o Cephalosporins- a small
percentage of people who get a reaction with penicillin will have a reaction when taking cephalosporins.
High risk population for gentamicin? - Ans:✔✔-patients w/renal impairment
Major adverse effects of gentamicin? - Ans:✔✔-Ototoxicity, nephrotoxicity.
gentamicin s/s of ototoxicity (HHTNV)? - Ans:✔✔--tinnitus, hearing loss, vertigo, headache, nausea.
(HHTNV)
Page 1/10
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Gentamicin- first sign of ototoxicity? - Ans:✔✔-h/a
What's the neuromuscular blockade reversal agent for gentamicin? - Ans:✔✔-IV calcium gluconate.
Therapeutic use for Fosfomycin? - Ans:✔✔-UTI-single dose
Drug interaction for Cefotetan? - Ans:✔✔-o ALCOHOL causes disulfiram reaction (flushing, palpitation,
nausea).
Adverse effect of Vancomycin? - Ans:✔✔-Red Man Syndrome, red from the torso up, V/S- hypotension,
tachycardia. This occurs when an infusion is given too quickly.
First-line drug use for tetracycline? - Ans:✔✔-o Rickettsia disease, Chlamydia, Lyme disease.
Adverse effects of tetracycline? - Ans:✔✔--Long bone suppression- suppresses growth in premature
infants
-teeth discoloration (for children under the age of eight)
-fetal harm in pregnant women & breast-feeding women (they must avoid this drug)
Food interaction with tetracycline? - Ans:✔✔-milk products suppress absorption
Adverse effect of trimethoprim/sulfamethoxazole (Bactrim)? - Ans:✔✔-o Kernicterus in neonates-
elevated bilirubin which can lead to cerebral palsy, hearing loss, and effect the teeth.
Page 2/10
FIRST PUBLISH OCTOBER 2024
NUR 545 Final Exam Practice Questions
and Answers
Drug interaction for penicillin? - Ans:✔✔-o Aminoglycosides- don't mix penicillin with this drug. Penicillin
deactivates aminoglycoside.
MOA for penicillin? - Ans:✔✔-o disrupts bacterial cells wall which leads to cell death
Adverse effect of penicillin? - Ans:✔✔-o anaphylactic reaction (s/s: SOB, rash, angioedema). Give
epinephrine when this occurs.
High-risk patients for penicillin - Ans:✔✔-o The elderly or renal impairment (reduce the dose)
What's the cross-reactivity with penicillin (beta lactam ring)? - Ans:✔✔-o Cephalosporins- a small
percentage of people who get a reaction with penicillin will have a reaction when taking cephalosporins.
High risk population for gentamicin? - Ans:✔✔-patients w/renal impairment
Major adverse effects of gentamicin? - Ans:✔✔-Ototoxicity, nephrotoxicity.
gentamicin s/s of ototoxicity (HHTNV)? - Ans:✔✔--tinnitus, hearing loss, vertigo, headache, nausea.
(HHTNV)
Page 1/10
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Gentamicin- first sign of ototoxicity? - Ans:✔✔-h/a
What's the neuromuscular blockade reversal agent for gentamicin? - Ans:✔✔-IV calcium gluconate.
Therapeutic use for Fosfomycin? - Ans:✔✔-UTI-single dose
Drug interaction for Cefotetan? - Ans:✔✔-o ALCOHOL causes disulfiram reaction (flushing, palpitation,
nausea).
Adverse effect of Vancomycin? - Ans:✔✔-Red Man Syndrome, red from the torso up, V/S- hypotension,
tachycardia. This occurs when an infusion is given too quickly.
First-line drug use for tetracycline? - Ans:✔✔-o Rickettsia disease, Chlamydia, Lyme disease.
Adverse effects of tetracycline? - Ans:✔✔--Long bone suppression- suppresses growth in premature
infants
-teeth discoloration (for children under the age of eight)
-fetal harm in pregnant women & breast-feeding women (they must avoid this drug)
Food interaction with tetracycline? - Ans:✔✔-milk products suppress absorption
Adverse effect of trimethoprim/sulfamethoxazole (Bactrim)? - Ans:✔✔-o Kernicterus in neonates-
elevated bilirubin which can lead to cerebral palsy, hearing loss, and effect the teeth.
Page 2/10
