NURP 424 Exam 2 Study Guide with Complete Solutions

NURP 424 Exam 2 Study Guide with Complete Solutions Benzyl Peroxide - Ans:-Fight P. Ance via free radicals, and dries and removes sebum NOT w/ Retinoids, can bleach clothes Arythromicin and Clindamicin - Ans:-Topical form interrupts protein synthesis NOT for Crohns, UC or coloitis (diarrhea) Azelaic Acid - Ans:-Topical, inhibits microbial proein synthesis, decreases inflammation, bacteria on skin, and keratinization CAUTION w/ darker skin Salicylic Acid - Ans:-OTC, for mild acne, anticondomal effect Retin-A - Ans:-Topical retinoid, decrease binding of keratinization and comedones, makes them open up Adapoline (differin) - Ans:-Topical retinoid, decrease microcomedone formation, controls cell differentiation, keratinization, and inflammation ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 2/27 Tazarotene - Ans:-Topical Retinoid, normalize differentiation and inflammation NOT for pregnancy Tetracycline - Ans:-Oral antibiotic for P. Acnes, comedones into pustules and papules, prevent leasions If contraindicatied: azithromycin, erythro or bactrim Isotretinoin (Accuntane) - Ans:-Oral Retinoid, reduces P. acnes, reduces sebum production, sebaceous gland size, and follicular keratinization Skin drying, cheilitis, triglyceride decrease, increase BGL, headaches, lethargy, fgiue, GI, visual distubances, arthralgia/myalgias NOT for pregnancy, risk for osteoporosis, ETOH use Topical Calcineurin Inhibbitors (Pimecrolimus & Tacrolimus) - Ans:-Steroid for atopic dermatitis, med or short term, supress T-cells and intracellular protein binding, decreasing cytokines and mast cells BLACK BOX w/ longterm use, CAUTION w/ preg, lact, , 2yo, immunosuppressed Toptical Corticosteroids - Ans:-Dermatitis and psoriasis, anti-inflammatory (depress histamine and prostaglandins), antipuritic, vasoconstrictive increased by occlusive dressing (oitment is best for absorbtion) ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 3/27 CAUTION w/ renal fuction, pregnancy and children, skin irriation (use emollients), watch for secondary infection Diphenhydramine (Benadryl) - Ans:-Duppress H1 receptors, local anestheptic (nerve impulses decreased) CAUTION over 7days, lactation NOT for children under 2, open skin (systemic) Doxepin (Zonalon) - Ans:-Blocks H1 and H2, for severe puritus CAUTION 10% + body use (drowsiness), elderly NOT for glaucoma, urinary retention, children, lactation Pyrethrins RTC - Ans:-Lice absorb through exoskeleton cause paralysis and death Washing hair will deactivate its NOT for ragweed allergy, children under 2 Permethrin - Ans:-Lice and scabies absorb throug exoskeleton x7 days WHOLE family for scabies NOT for children under 2mo ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 4/27 Malathione (Ovide) - Ans:-Lice vivo inhibited cholinesterase (kils lice and eggs) x7 days FLAMMABLE and Respiratory distress if inhaled NOT for children under 6yo, preg, or lactation Benzyl Alcohol - Ans:-Lice, non-neurotoxin, stuns lice asphyiate, only LIVE lice NOT for children 6mo Ivermectin - Ans:-Lice and Scabies, paralysis of nerve and muscle cells, single dose NOT for children under 6mo, avoid in preg and lactation Warfarin - Ans:-Competitively inhibits VKORC1, depleating Vit K, decreasing hepatic clotti