FIRST PUBLISH OCTOBER 2024
NURS 3080 Exam 1 Study Guide
Solutions
Dysplasia (atypical hyperplasia) - Ans:✔✔-Abnormal changes in size, shape, and organization of mature
cells
Metaplasia - Ans:✔✔-Reversible replacement of one mature cell type by another cell type, frequently
one less differentiated. Found in association with tissue damage, repair, and regeneration
Hypoxia - Ans:✔✔-the lack of sufficient oxygen within cells
Reactive Oxygen Species - Ans:✔✔-reactive molecules from molecular oxygen formed as a natural
oxidant species in cells during mitochondrial respiration and energy generation. Injury caused by this is
called oxidative stress
Blunt force injuries - Ans:✔✔-mechanical injury to body in tearing, shearing, or crushing caused by
blows/impacts
Abrasion - Ans:✔✔-surface layers of the skin (epidermis) has been broken; scrape
Lacerations - Ans:✔✔-tear or rip resulting when the strength of skin/tissue is exceeded; has ragged and
irregular with abraded edges
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FIRST PUBLISH OCTOBER 2024
Xenobiotics - Ans:✔✔-chemicals that have toxic, mutagenic, or carcinogenic properties
Caseous necrosis - Ans:✔✔-occurs when dead cells disintegrate, but the debris is not completely
hydrolyzed; soft and granular tissues form as the end-product, resembling clumped cheese
Coagulative necrosis - Ans:✔✔-occurs as a result of protein denaturation, where albumin is transformed
from a gelatinous, transparent state into a firm, opaque substance. Occurs most commonly in the HEART
Liquefactive necrosis - Ans:✔✔-results from ischemic injury to neurons and glial cells in the brain; causes
cells to be digested by their own hydrolases as the tissue becomes soft and liquified. Occurs most
commonly in the BRAIN
Fatty necrosis - Ans:✔✔-cellular dissolution caused by lipases, potent enzymes found in the breast and
abdominal structures, especially within the pancreas
Pallor mortis - Ans:✔✔-surface of the skin becomes pale and yellowish, marking the first stage after
death
Algor mortis - Ans:✔✔-The second stage after death that is defined as a decrease in body temperature
Rigor mortis - Ans:✔✔-The third stage after death that is characterized by stiffening of muscles
Livor mortis - Ans:✔✔-the fourth stage of death in which gravity causes blood to settle in dependent
tissues resulting in a prominent blue-purple discoloration of skin over these regions
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