NR 546 Neurotransmitter Table completed Week 8 With Complete 2024/2025
Solutions
,NR 546 Neurotransmitter Table completed Week 8 With Complete 2024/2025
Solutions
Neuro Receptor Location/Function/Effects Distribution Drug classes that Specific medications that target this
transmitter Subtype /symptoms of excess or (ie: CNS/PNS, target this neurotransmitter or receptor
deficit if applicable GI, vascular) neurotransmitter or
receptor
Glutamate AMPA α-Amino-3-hydroxy-5- CNS AMPA Receptor Perampanel
methyl-4- Antagonists
isoxazolepropionic acid
(AMPA)-type glutamate
receptors (AMPARs)
mediate the majority of
fast excitatory synaptic
transmission in the brain.
AMPA receptors are
abundant and widely
distributed in the central
nervous system.
Hippocampus, outer layer
of the cortex, basal
ganglia, olfactory regions,
lateral septum, and
amygdala of the CNS are
all enriched with GluA1,
GluA2, and GluA3
subunits.
MNDA N-methyl-D-aspartate CNS NDMA Glutamate NDMA Glutamate Antagonist-
(NMDA) receptors NMDA receptors Antagonist Memantine
represent one of the are found in Phencyclidine
ligand-gated non-selective both synaptic Ketamine
ionotropic glutamate and Dextromethorphan
receptors (iGluRs), which extrasynaptic Dextromethadone
, NR 546 Neurotransmitter Table completed Week 8 With Complete 2024/2025
Solutions
are present in high density locations on
within the hippocampus neurons. NMDA
and the cerebral cortex receptors also
N-methyl-D-aspartate can be found on
(NMDA) receptors, a neurons in early
family of L-glutamate stages prior to
receptors, play an synaptogenesis,
important role in learning where they may
and memory, and are be involved in
critical for spatial memory migration and
demonstrated differentiation.
deterioration in NMDA Extrasynaptic
receptor subunit NMDA receptors
expression and function typically are
with advancing age associated with
contacts with
adjacent
processes such
as axons and
glia
GABA GABA a Limbic system GABAa Benzodiazepines Zolpidem
GABAa is considered in receptors are Neuroactive Steroids Zaleplon
fast synaptic inhibition. located Zopiclone
throughout the Eszopiclone
central nervous Allepregnanolone
system
Serotonin 5HT 1a 5HT1A receptors are CNS partial 5-HT1A-R buspirone, gepirone, and
5HT located on GABA agonists tandospirone
interneurons in the
prefrontal cortex
5HT1A receptors can
promote the release of
Solutions
,NR 546 Neurotransmitter Table completed Week 8 With Complete 2024/2025
Solutions
Neuro Receptor Location/Function/Effects Distribution Drug classes that Specific medications that target this
transmitter Subtype /symptoms of excess or (ie: CNS/PNS, target this neurotransmitter or receptor
deficit if applicable GI, vascular) neurotransmitter or
receptor
Glutamate AMPA α-Amino-3-hydroxy-5- CNS AMPA Receptor Perampanel
methyl-4- Antagonists
isoxazolepropionic acid
(AMPA)-type glutamate
receptors (AMPARs)
mediate the majority of
fast excitatory synaptic
transmission in the brain.
AMPA receptors are
abundant and widely
distributed in the central
nervous system.
Hippocampus, outer layer
of the cortex, basal
ganglia, olfactory regions,
lateral septum, and
amygdala of the CNS are
all enriched with GluA1,
GluA2, and GluA3
subunits.
MNDA N-methyl-D-aspartate CNS NDMA Glutamate NDMA Glutamate Antagonist-
(NMDA) receptors NMDA receptors Antagonist Memantine
represent one of the are found in Phencyclidine
ligand-gated non-selective both synaptic Ketamine
ionotropic glutamate and Dextromethorphan
receptors (iGluRs), which extrasynaptic Dextromethadone
, NR 546 Neurotransmitter Table completed Week 8 With Complete 2024/2025
Solutions
are present in high density locations on
within the hippocampus neurons. NMDA
and the cerebral cortex receptors also
N-methyl-D-aspartate can be found on
(NMDA) receptors, a neurons in early
family of L-glutamate stages prior to
receptors, play an synaptogenesis,
important role in learning where they may
and memory, and are be involved in
critical for spatial memory migration and
demonstrated differentiation.
deterioration in NMDA Extrasynaptic
receptor subunit NMDA receptors
expression and function typically are
with advancing age associated with
contacts with
adjacent
processes such
as axons and
glia
GABA GABA a Limbic system GABAa Benzodiazepines Zolpidem
GABAa is considered in receptors are Neuroactive Steroids Zaleplon
fast synaptic inhibition. located Zopiclone
throughout the Eszopiclone
central nervous Allepregnanolone
system
Serotonin 5HT 1a 5HT1A receptors are CNS partial 5-HT1A-R buspirone, gepirone, and
5HT located on GABA agonists tandospirone
interneurons in the
prefrontal cortex
5HT1A receptors can
promote the release of
