Chapter 01
Multiple Choice
Identify the choice that best completes the statement or answers the question.
____ 1. The use of specific drugs to prevent, treat, or diagnose disease is known
as
a. toxicology
b. pharmacokinetics
c. pharmacotherapeutics
d. toxicokinetics
e. dynamic equilibrium
____ 2. The study of how the body deals with a drug in terms of the way the drug is absorbed, distributed, and
eliminated is known as
a. toxicology
b. pharmacodynamics
c. pharmacy
d. pharmacokinetics
e. biodynamics
____ 3. Toxicology is
a. the study of the harmful effects of chemicals
b. the study of a drug's beneficial effects
c. the analysis of drug absorption, distribution, and metabolism
d. the preparation and dispensing of therapeutic medications
e. the analysis of a drug's molecular structure
____ 4. The generic name of a drug
a. is also known as the “official” or “nonproprietary” name
b. is often derived from the chemical name
c. tends to be somewhat shorter than the drug's chemical name
d. all of the above are true
____ 5. If there is no existing patent for a drug, or if the patent has expired, the same drug may be marketed by
separate drug companies under different
a. chemical names
b. generic names
c. trade names
d. nonproprietary names
e. organic names
____ 6. The generic form of a drug is considered to be as safe and effective as the original, brand-name
product if the generic form _________ as the brand-name drug.
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, Pharmacology in Rehabilitation 5th Edition Test Bank
a. has the same type and amount of the active ingredient(s)
b. uses the same administration route
c. has the same pharmacokinetic profile (drug absorption, plasma levels, and so forth)
d. produces the same therapeutic effects
e. all the above are true
____ 7. During drug testing and approval, the drug is usually tested in a relatively small sample (200 to 300
people) with a specific disease or pathologic condition during
a. preclinical trials
b. phase 1 clinical trials
c. phase 2 clinical trials
d. postmarketing surveillance
____ 8. Drugs that can be purchased directly by the consumer without a prescription are also known as
a. nonproprietary medications
b. Schedule I controlled substances
c. Schedule II controlled substances
d. Schedule III controlled substances
e. over-the-counter drugs
____ 9. The point at which there is no further increase in the response to a drug even if the dosage continues to
be increased is known as the
a. ceiling effect
b. maximal efficacy
c. potency
d. all of the above
e. A and B only
____ 10. When two drugs are compared, the drug that requires a lower dosage to produce the same effect as a
higher dose of the second drug is said to
a. be more potent
b. be less potent
c. have a great maximal efficacy
d. have a greater therapeutic index
e. be pharmacosuperior
____ 11. When evaluating drug safety, the dosage that causes 50 percent of subjects to exhibit a specific
adverse effect is known as the
a. median therapeutic dose
b. median toxic dose
c. therapeutic index
d. ceiling effect
e. threshold dose
____ 12. In general, the greater the value of the _______, the safer the drug is considered to be.
a. median effective dose
b. threshold dose
c. therapeutic index (TI)
d. ceiling effect
e. potency index
____ 13. Regarding drug development and approval, an “orphan drug” is a drug that is
a. prescribed for conditions other than those approved by the FDA
b. given special funding for development because it is used in a small patient population with
a relatively rare disease
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, Pharmacology in Rehabilitation 5th Edition Test Bank
c. available directly to consumers without a prescription
d. only available in countries outside the United States
____ 14. Prescription use of a drug to treat conditions other than those that the drug was originally approved to
treat (off label prescribing)
a. is illegal and punishable by revoking a physician’s license
b. is legal only if the Center for Disease Control provides written permission to the physician
c. is legal only if the drug is not a controlled substance
d. is legal and quite common in the United States
e. is legal only after the patent for a drug has expired
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, Pharmacology in Rehabilitation 5th Edition Test Bank
Chapter 01
Answer Section
MULTIPLE CHOICE
1. ANS: C PTS: 1
2. ANS: D PTS: 1
3. ANS: A PTS: 1
4. ANS: D PTS: 1
5. ANS: C PTS: 1
6. ANS: E PTS: 1
7. ANS: C PTS: 1
8. ANS: E PTS: 1
9. ANS: E PTS: 1
10. ANS: A PTS: 1
11. ANS: B PTS: 1
12. ANS: C PTS: 1
13. ANS: B PTS: 1
14. ANS: D PTS: 1
Chapter 02
Multiple Choice
Identify the choice that best completes the statement or answers the question.
____ 1. All of the following are parenteral routes of drug administration EXCEPT the ____ route.
a. oral
b. inhalation
c. injection
d. topical
e. transdermal
____ 2. The ______ effect occurs when drugs are transported initially to the liver where a significant amount of the
drug may be metabolized and destroyed before the drug reaches its primary site of action.
a. malabsorptive
b. first pass
c. Bohr
d. bioequivalence
e. pharmacodynamic
____ 3. Iontophoresis, phonophoresis, and medicated patches all use the _____ route to administer drugs.
a. oral
b. inhalation
c. injection
d. transdermal
e. rectal
____ 4. This first pass effect is of particular concern when drugs are administered
a. topically
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